Transient changes in neural discharge patterns may enhance the separation of concurrent vowels with different fundamental frequencies

1994 ◽  
Vol 95 (5) ◽  
pp. 2842-2842 ◽  
Author(s):  
Peter Cariani ◽  
Bertrand Delgutte
2020 ◽  
Vol 129 (2) ◽  
pp. 230-237
Author(s):  
Tyler D. Vermeulen ◽  
Brooke M. Shafer ◽  
Anthony V. Incognito ◽  
Massimo Nardone ◽  
André L. Teixeira ◽  
...  

We characterize the occurrence of a square-wave discharge pattern of efferent muscle sympathetic nerve activity during a sinus pause in a young healthy male. This discharge pattern comprised large recruited action potential clusters undetected at baseline that continuously discharged during the sinus pause. Notably, this discharge pattern was still contained within a single cardiac cycle.


2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Stephen A. Klassen ◽  
Jacqueline K. Limberg ◽  
Sarah E. Baker ◽  
Wayne T. Nicholson ◽  
Timothy B. Curry ◽  
...  

2018 ◽  
Vol 596 (18) ◽  
pp. 4497-4510 ◽  
Author(s):  
Stephen A. Klassen ◽  
Jacqueline K. Limberg ◽  
Sarah E. Baker ◽  
Wayne T. Nicholson ◽  
Timothy B. Curry ◽  
...  

1988 ◽  
Vol 60 (4) ◽  
pp. 1285-1302 ◽  
Author(s):  
J. Hore ◽  
D. Flament

1. The relation between changes in motor cortex neural (MCN) discharge and the development of limb ataxia during cerebellar dysfunction was studied in 4 Cebus monkeys. Elbow movements with decreased accelerations or with tremor were produced by reversible cerebellar nuclear cooling. Discharge from 160 neurons was analyzed in detail. 2. During cerebellar cooling 37 of 80 neurons that discharged before movement onset decreased their phasic, but not their tonic, activity. This could not be explained by decreased peak velocities during cerebellar cooling. It is suggested that this decreased phasic discharge is related to the less abrupt onset and smaller magnitude of agonist EMG activity, and to the decreased initial accelerations, without decreased peak velocities, observed in limb movements during cerebellar dysfunction. This view implies that the cerebellum is involved in some way in the generation of commands to agonist alpha-motoneurons. 3. No evidence was found that 3- to 4-Hz cerebellar intention tremor is driven by a purely central oscillator. All 28 neurons that discharged strongly in relation to cerebellar tremor in movements responded strongly and reciprocally to limb perturbations. 4. A number of changes were observed during cerebellar nuclear cooling in kinematically related neural discharge associated with disordered elbow movements: an increase in discharge of some velocity- and acceleration-like neurons, a decrease in (reciprocal) inhibition, and a shift from an acceleration-like to a velocity-like discharge in some neurons. 5. Fourteen of 29 neurons with muscle-like discharge patterns discharged in a servoassistance-like manner during cerebellar dysfunction that was consistent with them contributing to tremor. 6. The results indicate that a variety of disorders, i.e., in the generation of central commands that initiate movements and in the regulation of the gain and phase of proprioceptive feedback, contribute to the development of limb ataxia during cerebellar dysfunction.


1988 ◽  
Vol 60 (4) ◽  
pp. 1268-1284 ◽  
Author(s):  
D. Flament ◽  
J. Hore

1. Bedingham and Tatton recently reported that in cats trained not to resist imposed limb perturbations, some motor cortex (area 4) neurons responded predominantly to acceleration or jerk (the third derivative of position). The questions arose whether motor cortex neurons responding to higher derivatives of limb displacement exist in the primate in a resist-perturbation task and, if so, whether discharge of such neurons responds to the same kinematics in active (voluntary) movements. 2. To answer these questions we studied the discharge patterns of 203 motor cortex neurons that responded to torque pulse perturbations about the elbow and fired during active elbow flexions and extensions in four monkeys. Detailed analysis was performed on 66 neurons that responded reciprocally in both situations. 3. Reciprocal neurons discharged at short latency (20-40 ms) for one direction of arm perturbation. For the opposite direction they were initially silent or inhibited and then discharged at a variety of latencies but in apparent relation to limb kinematics. Based on the timing and overall pattern of their discharge the majority of neurons (68%) were classified as being acceleration-like. 4. Twenty-four (36%) of these reciprocal neurons had only sensory (kinematic)-like properties in active movements, i.e., they discharged after (and not before) movement onset. Discharge of these neurons followed the timing, but not the magnitude, of acceleration (20 neurons) or velocity (4 neurons). The discharge of these neurons also had a static component as the arm was held stationary. 5. Twenty-nine (44%) of reciprocal neurons commenced firing before movement onset for one direction of active movement, while for the opposite direction their discharge occurred after movement onset. Thus their discharge appeared to be muscle-related: both when the muscle was contracting as an agonist and stretched as an antagonist. 6. Although in these tasks discharge of MCNs could be generated either by sensory feedback or by motor responses, the strong response sensitivity of many neurons to acceleration supports the hypothesis that feedback based on higher derivatives of limb displacement could represent a "predictive" control system for accurate regulation of limb motion.


1979 ◽  
Vol 10 (4) ◽  
pp. 246-248 ◽  
Author(s):  
Peter B. Mueller ◽  
Marla Adams ◽  
Jean Baehr-Rouse ◽  
Debbie Boos

Mean fundamental frequencies of male and female subjects obtained with FLORIDA I and a tape striation counting procedure were compared. The fundamental frequencies obtained with these two methods were similar and it appears that the tape striation counting procedure is a viable, simple, and inexpensive alternative to more costly and complicated procedures and instrumentation.


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