Ratio of variance to mean of action potential counts for an auditory nerve fiber model with second‐order refractory behavior

1993 ◽  
Vol 93 (4) ◽  
pp. 2035-2037 ◽  
Author(s):  
Roger P. Gaumond
Keyword(s):  
Action Potential ◽  
Nerve Fiber ◽  
Auditory Nerve ◽  
Second Order ◽  
Auditory Nerve Fiber ◽  
Fiber Model

scholarly journals Resolution of subcomponents of synaptic release from post-synaptic currents in rat hair-cell/auditory-nerve fiber synapses

2020 ◽  
Author(s):  
Eric D. Young ◽  
Jingjing Sherry Wu ◽  
Mamiko Niwa ◽  
Elisabeth Glowatzki
Keyword(s):  
Hair Cell ◽  
Nerve Fiber ◽  
Hair Cells ◽  
Auditory Nerve ◽  
Neurotransmitter Release ◽  
Auditory Nerve Fiber ◽  
Vesicle Release ◽  
Synaptic Currents ◽  
Synaptic Release

AbstractThe synapse between inner hair cells and auditory nerve fiber dendrites shows large EPSCs, which are either monophasic or multiphasic. Multiquantal or uniquantal flickering release have been proposed to underlie the unusual multiphasic waveforms. Here the nature of multiphasic waveforms is analyzed using EPSCs recorded in vitro in rat afferent dendrites. Spontaneous EPSCs were deconvolved into a sum of presumed release events with monophasic EPSC waveforms. Results include: first, the charge of EPSCs is about the same for multiphasic versus monophasic EPSCs. Second, EPSC amplitudes decline with the number of release events per EPSC. Third, there is no evidence of a mini-EPSC. Most results can be accounted for by versions of either uniquantal or multiquantal release. However, serial neurotransmitter release in multiphasic EPSCs shows properties that are not fully explained by either model, especially that the amplitudes of individual release events is established at the beginning of a multiphasic EPSC, constraining possible models of vesicle release.

Auditory nerve fiber responses following chronic cochlear de-efferentation

1999 ◽  
Vol 406 (1) ◽  
pp. 72-86 ◽  
Author(s):  
Xiang Yang Zheng ◽  
Donald Henderson ◽  
Sandra L. McFadden ◽  
Da Lian Ding ◽  
Richard J. Salvi
Keyword(s):  
Nerve Fiber ◽  
Auditory Nerve ◽  
Auditory Nerve Fiber
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