scholarly journals Comparison of cochlear delay estimates using otoacoustic emissions and auditory brainstem responses

2009 ◽  
Vol 126 (3) ◽  
pp. 1291-1301 ◽  
Author(s):  
James M. Harte ◽  
Gilles Pigasse ◽  
Torsten Dau
Keyword(s):  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses

Audiological findings in glomus tumours

1997 ◽  
Vol 111 (3) ◽  
pp. 218-222 ◽  
Author(s):  
William W. Qiu ◽  
Shengguang S. Yin ◽  
Fred J. Stucker ◽  
Mardjohan Hardjasudarma
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Auditory System ◽  
Middle Ear ◽  
Otoacoustic Emissions ◽  
Cerebellopontine Angle ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

AbstractGlomus tumours involving the middle ear and the cerebellopontine angle are reported with emphasis on audiological findings. Magnetic resonance imaging (MRI), angiographic and pathological results are presented. Audiological tests, including impedance audiometry, evoked otoacoustic emissions and auditory brainstem responses, are valuable in evaluation of the effect of glomus tumours on the auditory system as well as their pathological extent.

Μελέτη των παραγόντων υψηλού κινδύνου για εμφάνιση βαρηκοΐας σε νεογνά της μονάδας εντατικής νοσηλείας

2016 ◽  
Author(s):  
Εμμανουήλ Νησωτάκης
Keyword(s):  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Transiently Evoked Otoacoustic Emissions

Εισαγωγή Η συγγενής βαρηκοΐα είναι ίσως η πιο συχνή αισθητηριακή βλάβη της νεογνικής ηλικίας. Τα νοσηλευόμενα στη ΜΕΝΝ νεογνά θεωρείται ότι διατρέχουν μεγαλύτερο κίνδυνο για εμφάνιση είτε νευροαισθητήριας βαρηκοΐας είτε ακουστικής νευροπάθειας. Η σοβαρότητα της απώλειας ακοής κατά τη διάρκεια της πρώιμης κρίσιμης περιόδου ανάπτυξης του λόγου καθορίζει την απόκτηση επαρκούς γλωσσικής ικανότητας γι’ αυτό και είναι σημαντική η έγκαιρη διάγνωση και αντιμετώπιση κάθε υποκείμενης ακουστικής διαταραχής.Στη μελέτη αυτή εστιάζουμε στην παρουσία ακοολογικών παραγόντων κινδύνου και προσπαθούμε να διευκρινίσουμε την συσχέτισή τους με την εμφάνιση συγγενούς βαρηκοΐας, συμπεριλαμβανομένης και της ακουστικής νευροπάθειας, στον πληθυσμό των νεογνών της ΜΕΝΝ του νοσοκομείου μας.Ασθενείς και ΜέθοδοςΣτην παρούσα προοπτική μελέτη κοόρτης μελετήθηκαν 453 νεογνά τα οποία εισήχθησαν στη ΜΕΝΝ για περισσότερο από 24 ώρες μεταξύ 2012 και 2016 και εμφάνιζαν έναν ή περισσότερους παράγοντες κινδύνου. Όλα τα νεογνά υποβλήθηκαν σε ακοολογικό έλεγχο με χρήση αυτοματοποιημένων προκλητών δυναμικών του εγκεφαλικού στελέχους (automated Auditory Brainstem Responses – aABRs) σε συνδυασμό με παροδικά προκλητές ωτοακουστικές εκπομπές (Transiently Evoked OtoAcoustic Emissions – TEOAEs) τουλάχιστον 48 ώρες μετά τη γέννησή τους. Τα νεογνά που απέτυχαν στην αρχική εξέταση επανεξετάζονταν πριν τον πρώτο μήνα ζωής κι επί αποτυχίας παραπέμπονταν στο ιατρείο παιδικής βαρηκοΐας για πλήρη ακοολογικό έλεγχο. ΑποτελέσματαΑπό τον συνολικό αριθμό των 453 νεογνών 71 απέτυχαν στον αρχικό ακοολογικό έλεγχο. Μόνο 49 προσήλθαν για επανεξέταση και τελικά 8 νεογνά (1.8%) απέτυχαν τόσο στα a-ABRs όσο και στις TEOAEs και διαγνώσθηκαν με πιθανή νευροαισθητήρια βαρηκοΐα, ενώ σε επίσης 8 νεογνά (1.8%) οι TEOAEs εκλύθηκαν φυσιολογικά αλλά απέτυχαν στα a-ABRs οπότε διαγνώσθηκαν με πιθανή ακουστική νευροπάθεια. Από τους 13 ανεξάρτητους παράγοντες κινδύνου που ελέγχθηκαν η ωτοτοξικότητα των χορηγούμενων φαρμάκων, η μηχανική υποστήριξη της αναπνοής, το χαμηλό βάρος γέννησης και η υπερχολερυθριναιμία ήταν οι πιο συχνά εμφανιζόμενοι. Η πλειοψηφία των νεογνών (48%) εμφάνιζε ταυτόχρονα δύο παράγοντες κινδύνου. Το χαμηλό βάρος γέννησης βρέθηκε να συσχετίζεται με την εμφάνιση πιθανής νευροαισθητήριας βαρηκοΐας (p=0.002), ενώ οι κρανιοπροσωπικές ανωμαλίες και οι λοιμώξεις της ομάδας TORCH παρουσίασαν στατιστικά σημαντική συμμετοχή (p=0.03 και p=0.05 αντίστοιχα) στην ανάπτυξη πιθανής απώλειας ακοής συμπεριλαμβανομένης και της ακουστικής νευροπάθειας.ΣυμπεράσματαΤα προκλητά δυναμικά του εγκεφαλικού στελέχους (ABRs) και οι ωτοακουστικές εκπομπές (OAEs) αποτελούν τους θεμέλιους λίθους του καθολικού νεογνικού ελέγχου ακοής στη ΜΕΝΝ καθώς σημαντικός αριθμός παιδιών μπορεί να πάσχει από ακουστική νευροπάθεια. Η συνεχής επανεξέταση των παραγόντων κινδύνου και της συμβολής τους στην εμφάνιση βαρηκοΐας κρίνεται απαραίτητη καθώς αυτοί μεταβάλλονται. Απαιτείται ένα αποδοτικό σύστημα γραμματειακής υποστήριξης προκειμένου να ελαττωθεί το ποσοστό των νεογνών που δεν προσέρχονται για επανεξέταση.

scholarly journals Auditory neuropathy in a patient exposed to xylene: case report

2008 ◽  
Vol 123 (4) ◽  
pp. 462-465 ◽  
Author(s):  
T H J Draper ◽  
D-E Bamiou
Keyword(s):  
Case Report ◽  
Otoacoustic Emissions ◽  
Auditory Pathway ◽  
Auditory Brainstem ◽  
Auditory Neuropathy ◽  
Auditory Brainstem Responses ◽  
Test Results ◽  
Solvent Exposure ◽  
Complex Sounds ◽  
Acoustic Reflexes

AbstractObjective:To report the case of an adult patient who developed auditory complaints following xylene exposure, and to review the literature on the effects of solvent exposure on hearing.Case report:The patient presented with a gradual deterioration in his ability to hear in difficult acoustic environments and also to hear complex sounds such as music, over a 40-year period. His symptoms began following exposure to the solvent xylene, and in the absence of any other risk factor. Our audiological investigations revealed normal otoacoustic emissions with absent auditory brainstem responses and absent acoustic reflexes in both ears, consistent with a diagnosis of bilateral auditory neuropathy. Central test results were also abnormal, indicating possible involvement of the central auditory pathway.Conclusions:To our knowledge, this is the first report of retrocochlear hearing loss following xylene exposure. The test results may provide some insight into the effect of xylene as an isolated agent on the human auditory pathway.

Differences in Responses from the Cochleae and Central Nervous Systems of Females with Low versus High Acceptable Noise Levels

2006 ◽  
Vol 17 (09) ◽  
pp. 667-676 ◽  
Author(s):  
Ashley W. Harkrider ◽  
Joanna W. Tampas
Keyword(s):  
Auditory System ◽  
Background Noise ◽  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Intersubject Variability ◽  
Hearing Sensitivity ◽  
Central Regions ◽  
Central Nervous Systems ◽  
Medial Olivocochlear

Studies of acceptable noise level (ANL) consistently report large intersubject variability in acceptance of background noise while listening to speech. This variability is not related to age, gender, hearing sensitivity, type of background noise, speech perception in noise performance, or efferent activity of the medial olivocochlear pathway. An exploratory study was conducted to determine if differences in aggregate responses from the peripheral and central auditory system can account for intersubject variability in ANL. Click-evoked otoacoustic emissions (CEOAEs), binaural auditory brainstem responses (ABRs), and middle latency responses (MLRs) were measured in females with normal hearing with low (n = 6) versus high (n = 7) ANLs. Results of this preliminary study indicate no differences between the groups for CEOAEs or waves I or III of the ABR. Differences between the two groups emerge for the amplitudes of wave V of the ABR and for the Na-Pa component of the MLR, suggesting that physiological variations arising from more central regions of the auditory system may mediate background noise acceptance.

scholarly journals Otoacoustic emissions and auditory brainstem responses in the newborn.

1991 ◽  
Vol 66 (10 Spec No) ◽  
pp. 1124-1129 ◽  
Author(s):  
C R Kennedy ◽  
L Kimm ◽  
D C Dees ◽  
P I Evans ◽  
M Hunter ◽  
...  
Keyword(s):  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses

scholarly journals Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251363
Author(s):  
Dennis McFadden ◽  
Craig A. Champlin ◽  
Michelle H. Pho ◽  
Edward G. Pasanen ◽  
Mindy M. Maloney ◽  
...  
Keyword(s):  
Sex Differences ◽  
Menstrual Cycle ◽  
Evoked Potentials ◽  
Otoacoustic Emissions ◽  
Auditory Evoked Potentials ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Hearing Level ◽  
Behavioral Performance ◽  
The Waves

Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between the AEP measures and measures of otoacoustic emissions (OAEs) and behavioral performance also measured on the same subjects. Also of interest was how the menstrual cycle affected the various AEP measures. Most ABR measures and several AMLR measures exhibited sex differences, and many of the former were substantial. The sex differences tended to be larger for latency than for amplitude of the waves, and they tended to be larger for a weak click stimulus than for a strong click. The largest sex difference was for Wave-V latency (effect size ~1.2). When subjects were dichotomized into Non-Whites and Whites, the race differences in AEPs were small within sex. However, sex and race interacted so that the sex differences often were larger for the White subjects than for the Non-White subjects, particularly for the latency measures. Contrary to the literature, no AEP measures differed markedly across the menstrual cycle. Correlations between various AEP measures, and between AEP and OAE measures, were small and showed no consistent patterns across sex or race categories. Performance on seven common psychoacoustical tasks was only weakly correlated with individual AEP measures (just as was true for the OAEs also measured on these subjects). AMLR Wave Pa unexpectedly did not show the decrease in latency and increase in amplitude typically observed for AEPs when click level was varied from 40 to 70 dB nHL (normal Hearing Level). For the majority of the measures, the variability of the distribution of scores was greater for the males than for the females.

Newborn Hearing Screening with Combined Otoacoustic Emissions and Auditory Brainstem Responses

2004 ◽  
Vol 15 (06) ◽  
pp. 414-425 ◽  
Author(s):  
James W. Hall ◽  
Steven D. Smith ◽  
Gerald R. Popelka
Keyword(s):  
Auditory Brainstem Response ◽  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Hearing Screening ◽  
Auditory Neuropathy ◽  
Diagnostic Evaluation ◽  
Auditory Brainstem Responses ◽  
Conductive Loss ◽  
Brainstem Response ◽  
Screening Measures

Accurate assessment of neonatal hearing screening performance is impossible without knowledge of the true status of hearing, a prohibitive requirement that necessitates a complete diagnostic evaluation on all babies screened. The purpose of this study was to circumvent this limitation by integrating two types of screening measures obtained near simultaneously on every baby. Peripheral auditory function was defined by otoacoustic emission results. A complete diagnostic evaluation was performed on every baby who received a "Refer" outcome for auditory brainstem response screening. The integrated results for auditory brainstem response screening in an unselected group of 300 newborns estimated sensitivity at 100%, specificity at 99.7%, overall referral rate at 2.0%, and a positive predictive value of 83.3%. Conductive loss associated with amniotic fluid in the middle ear can persist several weeks after birth; conductive loss can produce a "Refer" outcome for auditory brainstem response screening; and auditory neuropathy can be detected with screening measures. Prevalence results were consistent with the published literature. The implications of this study are that otoacoustic emissions and auditory brainstem measures provide much more information than either alone and that both are needed for a comprehensive hearing screening program.

R449 – The Role of DPZF in Inner Ear Development and Function

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P195-P195
Author(s):  
Gao Xia
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Inner Ear ◽  
Hair Cells ◽  
Otoacoustic Emissions ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Inner Ear Development ◽  
Scanning Electron

Problem The dendritic cell-derived BTB/POZ zinc finger (DPZF) protein belongs to the C2H2 zinc finger protein transcription factor family. It is localized on chromosome 3 and widely expressed in hematopoietic tissues, including human dendritic cells (DC), monocytes, B cells and T cells. DPZF null mice (DPZF-/-) exhibit a circling phenotype, suggestive of an inner ear defect. Here, we present our work on the role of DPZF in hearing defects. Methods We used auditory brainstem responses (ABR) and distortion production otoacoustic emissions (DPOAEs) to test the hearing function of DPZF-/- mice, then gross observation and histopathology analysis including serial sections and scanning electron microscopy were performed to exam the cochlea of DPZF-/- mice. Results Auditory brainstem responses (ABR) and distortion production otoacoustic emissions (DPOAEs) showed that DPZF-/-mice were completely deaf. Disorganized and fewer hair cells of the Corti organ in DPZF-/- mice were identified by scanning electron microscopy. Besides, although the hair cells of the utricle and saccule were grossly normal, the stereocilia were greatly reduced in number. Further more, lipofuscin was seen in the stria vascularis with the amount of which increased with age. Conclusion The impaired hearing and balance function and the morphological abnormalities of inner ears are caused by the deletion of DPZF gene. Significance DPZF gene may participates in regulating inner ear development and the DPZF null mice may serve as a new disease model of hearing loss. Support This work was supported by the ground of Jiangsu Province Famous Doctor Project(RC2007010).

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