Analysis of frequency dependence of ultrasonic backscatter coefficient in cancellous bone

2008 ◽  
Vol 124 (6) ◽  
pp. 4083-4090 ◽  
Author(s):  
Dean Ta ◽  
Weiqi Wang ◽  
Kai Huang ◽  
Yuanyuan Wang ◽  
Lawrence H. Le
Keyword(s):  
Frequency Dependence ◽  
Cancellous Bone ◽  
Backscatter Coefficient ◽  
Ultrasonic Backscatter

scholarly journals Variability in Ultrasound Backscatter Induced by Trabecular Microstructure Deterioration in Cancellous Bone

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Xingxing Chou ◽  
Feng Xu ◽  
Ying Li ◽  
Chengcheng Liu ◽  
Dean Ta ◽  
...  
Keyword(s):  
Cancellous Bone ◽  
Fdtd Method ◽  
Bone Microstructure ◽  
Backscatter Coefficient ◽  
Backscatter Signal ◽  
Trabecular Microstructure ◽  
Ultrasound Backscatter ◽  
Ultrasonic Backscatter ◽  
The Relationship ◽  
Difference Time

To determine the relationship between the ultrasonic backscatter parameters and trabecular microstructural variations in cancellous bone, three erosion procedures were performed to simulate various changes in the cancellous bone microstructure. The finite difference time domain (FDTD) method was used to simulate the backscatter signal in cancellous bone. Ultrasonic backscatter properties were derived as functions of the porosity when the ultrasound incident directions were perpendicular and parallel to the major trabeculae direction (MTD), respectively. The variability in the apparent backscatter coefficient (ABC) and apparent integrated backscatter (AIB) due to the trabecular microstructure was revealed. Significant negative correlations between the backscatter parameters (ABC and AIB) and the porosity of the cancellous bone were observed. The simulations showed that the ABC and AIB were influenced by the direction of the trabecular microstructural variations. The linear regressions between the ultrasonic backscatter parameters (ABC and AIB) and the porosity showed significantly different slopes for three erosion procedures when they are ultrasonically perpendicular (for ABC, −1.22 dB, −0.98 dB, and −0.46 dB; for AIB, −0.74 dB, −0.69 dB, and −0.25 dB) and parallel (for ABC, −1.87 dB, −0.69 dB, and −0.51 dB; for AIB, −0.9 dB, −0.5 dB, and −0.34 dB) to the MTD. This paper investigated the relationship between ultrasonic backscatter and cancellous bone microstructure deterioration and indicated that the ultrasonic backscatter could be affected by cancellous bone microstructure deterioration direction.

PIO 7406 Ultrasonic backscatter coefficient in human cancellous bone in vivo

1997 ◽  
Vol 23 ◽  
pp. S135 ◽  
Author(s):  
P. Laugier ◽  
P. Giat ◽  
C. Chappard ◽  
Ch. Roux ◽  
G. Berger
Keyword(s):  
Cancellous Bone ◽  
Backscatter Coefficient ◽  
Human Cancellous Bone ◽  
Ultrasonic Backscatter

scholarly journals A Combined Ultrasonic Backscatter Parameter for Bone Status Evaluation in Neonates

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Weiying Mao ◽  
Yang Du ◽  
Chengcheng Liu ◽  
Boyi Li ◽  
Dean Ta ◽  
...  
Keyword(s):  
Gestational Age ◽  
Bone Health ◽  
Biochemical Markers ◽  
Age Groups ◽  
Backscatter Coefficient ◽  
Anthropometric Indices ◽  
Term Infants ◽  
Bone Status ◽  
Centroid Shift ◽  
Ultrasonic Backscatter

Metabolic bone disease (MBD) is one of the major complications of prematurity. Ultrasonic backscatter technique has the potential to be a portable and noninvasive method for early diagnosis of MBD. This study firstly applied CAS to neonates, which was defined as a linear combination of the apparent integrated backscatter coefficient (AIB) and spectral centroid shift (SCS). The objective was to evaluate the feasibility of ultrasonic backscatter technique for assessing neonatal bone health using AIB, SCS, and CAS. Ultrasonic backscatter measurements at 3.5 MHz, 5.0 MHz, and 7.5 MHz were performed on a total of 505 newborns within 48 hours after birth. The values of backscatter parameters were calculated and compared among gestational age groups. Correlations between backscatter parameters, gestational age, anthropometric indices, and biochemical markers were analyzed. The optimal predicting models for CAS were determined. The results showed term infants had lower SCS and higher AIB and CAS than preterm infants. Gestational age and anthropometric indices were negatively correlated with SCS (|r| = 0.45 – 0.57, P < 0.001), and positively correlated with AIB (|r| = 0.36 – 0.60, P < 0.001) and CAS (|r| = 0.56 – 0.69, P < 0.001). Biochemical markers yielded weak or nonsignificant correlations with backscatter parameters. CAS had relatively stronger correlations with the neonatal variables than AIB and SCS. At 3.5 MHz and 5.0 MHz, only gestational age (P < 0.001) independently contributed to the measurements of CAS, and could explain up to 40.5% – 44.3% of CAS variation. At 7.5 MHz, the combination of gestational age (P < 0.001), head circumference (P = 0.002), and serum calcium (P = 0.037) explained up to 40.3% of CAS variation. This study suggested ultrasonic backscatter technique was feasible to evaluate neonatal bone status. CAS was a promising parameter to provide more information about bone health than AIB or SCS alone.

scholarly journals Ultrasonic Backscatter Technique for Assessing and Monitoring Neonatal Cancellous Bone Status in Vivo

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 157417-157426 ◽  
Author(s):  
Weiying Mao ◽  
Yang Du ◽  
Chengcheng Liu ◽  
Boyi Li ◽  
Dean Ta ◽  
...  
Keyword(s):  
Cancellous Bone ◽  
Bone Status ◽  
Ultrasonic Backscatter
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