Dual frequency ultrasound technique enables determination of soft tissue composition and improves reliability of in vivo ultrasound bone densitometry

2008 ◽  
Vol 123 (5) ◽  
pp. 3638-3638
Author(s):  
Janne P. Karjalainen ◽  
Juha Töyräs ◽  
Toni Rikkonen ◽  
Jukka Jurvelin ◽  
Ossi Riekkinen
Keyword(s):  
Soft Tissue ◽  
Bone Densitometry ◽  
Tissue Composition ◽  
Dual Frequency ◽  
Ultrasound Technique ◽  
Soft Tissue Composition ◽  
Ultrasound Bone ◽  
Frequency Ultrasound

Dual-frequency ultrasound technique minimizes errors induced by soft tissue in ultrasound bone densitometry

2008 ◽  
Vol 49 (9) ◽  
pp. 1038-1041 ◽  
Author(s):  
J. Karjalainen ◽  
J. Töyräs ◽  
T. Rikkonen ◽  
J.S. Jurvelin ◽  
O. Riekkinen
Keyword(s):  
Soft Tissue ◽  
Tissue Composition ◽  
Dual Frequency ◽  
Ultrasound Technique ◽  
Bone Ultrasound ◽  
Soft Tissue Composition ◽  
Transmission Measurements ◽  
Frequency Ultrasound

Background: Most bone ultrasound devices are designed for through-transmission measurements of the calcaneus. In principle, ultrasound backscattering measurements are possible at more typical fracture sites of the central skeleton. Unfortunately, soft tissue overlying the bones diminishes reliability of these measurements. Purpose: To apply the single-transducer dual-frequency ultrasound (DFUS) technique to eliminate the errors induced by soft tissue on the measurements of integrated reflection coefficient (IRC) in human distal femur in vivo. Material and Methods: Ultrasound and dual-energy X-ray absorptiometry (DXA) examinations were conducted on a bodybuilder during a 21-week training and dieting period. Results: Significant changes in quantity and composition of soft tissue took place during the diet. However, DXA measurements showed no significant effects on bone density measurements. The single transducer DFUS technique enabled the determination of local soft-tissue composition, as verified by comparison with the DXA ( r=0.91, n=8, p<0.01). Further, the technique eliminated the soft-tissue-induced error from IRC measured for the bone. The uncorrected IRC associated significantly with the change in local soft-tissue composition ( r=−0.83, n=8, p<0.05), whereas the corrected IRC values showed no significant dependence ( r=−0.30, n=8, p=0.46) on local soft-tissue composition. Conclusion: The DFUS technique may significantly enhance the accuracy of clinical ultrasound measurements of bone.

Treatment of Murine Tumors Using Dual-Frequency Ultrasound in an Experimental in Vivo Model

2009 ◽  
Vol 35 (5) ◽  
pp. 756-763 ◽  
Author(s):  
Amir H. Barati ◽  
Manijhe Mokhtari-Dizaji ◽  
Hossein Mozdarani ◽  
S. Zahra Bathaie ◽  
Zuhair M. Hassan
Keyword(s):  
In Vivo Model ◽  
Dual Frequency ◽  
Murine Tumors ◽  
Frequency Ultrasound

scholarly journals Evaluation of the effect of soft tissue composition on the characteristics of spread-out Bragg peak in proton therapy

2016 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
SayyedBijan Jia ◽  
Mahdi Ghorbani ◽  
Mohsen Khosroabadi ◽  
HamidReza Sadoughi ◽  
Courtney Knaup
Keyword(s):  
Soft Tissue ◽  
Proton Therapy ◽  
Bragg Peak ◽  
Tissue Composition ◽  
Soft Tissue Composition ◽  
Spread Out Bragg Peak
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