Ultrasonic Reduction of Mitotic Activity in Regenerating Rat Liver

1973 ◽  
Vol 54 (1) ◽  
pp. 297-297
Author(s):  
F. W. Kremkau ◽  
R. L. Witcofski ◽  
I. Meschan
1970 ◽  
Vol 119 (4) ◽  
pp. 743-747 ◽  
Author(s):  
Göran Fex

The concentration and composition of phospholipids and mitotic activity in regenerating rat liver were studied. (1) The total amount of liver phospholipid increased approximately linearly during 48h after operation but without change in the relative concentrations of individual phospholipids. (2) The appearance of mitoses 30h after operation was accompanied by an increased incorporation of 32P into the liver phospholipids. (3) The regenerating livers incorporated a higher percentage of the label into the phosphatidylserine+phosphatidylinositol fraction than those of control rats. The percentage of the label incorporated into phosphatidylethanolamine in these livers increased but decreased in the phosphatidylcholine.


1974 ◽  
Vol 30 (5) ◽  
pp. 562-563 ◽  
Author(s):  
M. Japundžić ◽  
B. D. Garg ◽  
K. Kovac ◽  
I. Japundžić

1968 ◽  
Vol 59 (1) ◽  
pp. 10-22 ◽  
Author(s):  
Jan W. Guzek

ABSTRACT Both cortisone and ACTH inhibit the incorporation of 3H-thymidine into the DNA of parenchymatous cells in the regenerating rat liver. In addition, the mitotic activity of hepatocytes is markedly impaired. It is assumed that the suppression of mitoses in the regenerating rat liver, caused by cortisone or ACTH, is due to a direct or indirect interference with DNA synthesis.


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