scholarly journals Simulation of a Brownian particle in an optical trap

2013 ◽  
Vol 81 (3) ◽  
pp. 224-230 ◽  
Author(s):  
Giorgio Volpe ◽  
Giovanni Volpe
2015 ◽  
Author(s):  
Ignacio A. Martinez ◽  
Édgar Roldán ◽  
Luis Dinis ◽  
Pau Mestres ◽  
Juan M. R. Parrondo ◽  
...  

2021 ◽  
Vol 2021 (11) ◽  
pp. 113205
Author(s):  
Matthieu Mangeat ◽  
Thomas Guérin ◽  
David S Dean

Abstract Optically trapped particles are often subject to a non-conservative scattering force arising from radiation pressure. In this paper, we present an exact solution for the steady state statistics of an overdamped Brownian particle subjected to a commonly used force field model for an optical trap. The model is the simplest of its kind that takes into account non-conservative forces. In particular, we present the exact results for certain marginals of the full three-dimensional steady state probability distribution, in addition to results for the toroidal probability currents that are present in the steady state, as well as for the circulation of these currents. Our analytical results are confirmed by numerical solution of the steady state Fokker–Planck equation.


Life ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 515
Author(s):  
Andrea Cugno ◽  
Alex Marki ◽  
Klaus Ley

Leukocytes, including neutrophils, which are propelled by blood flow, can roll on inflamed endothelium using transient bonds between selectins and their ligands, and integrins and their ligands. When such receptor–ligand bonds last long enough, the leukocyte microvilli become extended and eventually form thin, 20 m long tethers. Tether formation can be observed in blood vessels in vivo and in microfluidic flow chambers. Tethers can also be extracted using micropipette aspiration, biomembrane force probe, optical trap, or atomic force microscopy approaches. Here, we review the biomechanical properties of leukocyte tethers as gleaned from such measurements and discuss the advantages and disadvantages of each approach. We also review and discuss viscoelastic models that describe the dependence of tether formation on time, force, rate of loading, and cell activation. We close by emphasizing the need to combine experimental observations with quantitative models and computer simulations to understand how tether formation is affected by membrane tension, membrane reservoir, and interactions of the membrane with the cytoskeleton.


Author(s):  
J. G. H. Franssen ◽  
T. C. H. de Raadt ◽  
M. A. W. van Ninhuijs ◽  
O. J. Luiten

2021 ◽  
Vol 103 (5) ◽  
Author(s):  
Yuki Miyazawa ◽  
Ryotaro Inoue ◽  
Hiroki Matsui ◽  
Kenta Takanashi ◽  
Mikio Kozuma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
John A. C. Albay ◽  
Zhi-Yi Zhou ◽  
Cheng-Hung Chang ◽  
Yonggun Jun

AbstractAlthough the equivalence of heat and work has been unveiled since Joule’s ingenious experiment in 1845, they rarely originate from the same source in experiments. In this study, we theoretically and experimentally demonstrated how to use a high-precision optical feedback trap to combine the generation of virtual temperature and potential to simultaneously manipulate the heat and work of a small system. This idea was applied to a microscopic Stirling engine consisting of a Brownian particle under a time-varying confining potential and temperature. The experimental results justified the position and the velocity equipartition theorem, confirmed several theoretically predicted energetics, and revealed the engine efficiency as well as its trade-off relation with the output power. The small theory–experiment discrepancy and high flexibility of the swift change of the particle condition highlight the advantage of this optical technique and prove it to be an efficient way for exploring heat and work-related issues in the modern thermodynamics for small systems.


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