Intensity modulated radiotherapy with charged particle beams: Studies of inverse treatment planning for rotation therapy

2000 ◽  
Vol 27 (6) ◽  
pp. 1246-1257 ◽  
Author(s):  
U. Oelfke ◽  
T. Bortfeld
Keyword(s):  
Charged Particle ◽  
Treatment Planning ◽  
Intensity Modulated Radiotherapy ◽  
Particle Beams ◽  
Inverse Treatment Planning ◽  
Charged Particle Beams ◽  
Intensity Modulated ◽  
Inverse Treatment

Three dimensional intensity modulated brachytherapy (IMBT): Dosimetry algorithm and inverse treatment planning

2010 ◽  
Vol 37 (7Part1) ◽  
pp. 3725-3737 ◽  
Author(s):  
Chengyu Shi ◽  
Bingqi Guo ◽  
Chih-Yao Cheng ◽  
Carlos Esquivel ◽  
Tony Eng ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Three Dimensional ◽  
Inverse Treatment Planning ◽  
Intensity Modulated ◽  
Inverse Treatment

SU-GG-T-38: Dosimetry and Inverse Treatment Planning for 3D Intensity Modulated Brachytherapy

2010 ◽  
Vol 37 (6Part15) ◽  
pp. 3192-3192
Author(s):  
B Guo ◽  
C Shi ◽  
C Cheng ◽  
C Esquivel ◽  
T Eng ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Inverse Treatment Planning ◽  
Intensity Modulated ◽  
Inverse Treatment

Provision of IMRT in the UK. Part 2: Current levels, planned expansion and obstacles to implementation

2003 ◽  
Vol 3 (4) ◽  
pp. 181-184 ◽  
Author(s):  
C.R. Baker ◽  
V. Hardy
Keyword(s):  
Treatment Planning ◽  
Intensity Modulated Radiotherapy ◽  
Implementation Process ◽  
Inverse Treatment Planning ◽  
Training Requirements ◽  
Patient Capacity ◽  
Inverse Treatment ◽  
Treatment Planning Systems ◽  
Time Required ◽  
The Uk

UK Radiotherapy Departments have been surveyed to establish the current level of provision of intensity-modulated radiotherapy (IMRT) and its expected growth in the next 2 to 5 years. At the time of writing, nine UK Departments have implemented IMRT, providing a national capacity of approximately 20 new patients per month. By 2005, a further nine Departments expect to have implemented IMRT. As confidence and experience of IMRT grows, streamlining of quality control (QC) and the development of class solutions for inverse treatment planning are expected to significantly reduce the preparation time required for each patient and so increase patient capacity in all Departments.Staff training requirements, extra workloads in treatment planning and QC, identification of inverse planning parameters and current limitations of inverse treatment planning systems were identified as the key learning points for Departments that have been through the implementation process. Obstacles identified as preventing early implementation include equipment availability, staff shortages and heavy clinical workloads limiting the amount of time available for implementation.

Optimization of Physical Dose Distributions with Hadron Beams: Comparing Photon IMRT with IMPT

2003 ◽  
Vol 2 (5) ◽  
pp. 401-412 ◽  
Author(s):  
U. Oelfke ◽  
T. Bortfeld
Keyword(s):  
Charged Particles ◽  
Intensity Modulated Radiotherapy ◽  
3D Scanning ◽  
Ion Beams ◽  
Carbon Ions ◽  
Dose Delivery ◽  
Dose Distributions ◽  
Inverse Treatment Planning ◽  
Intensity Modulated ◽  
Inverse Treatment

Intensity modulated radiotherapy with high enengy photons (IMRT) and with charged particles (IMPT) refer to the most advanced development in conformal radiation therapy. Their general aim is to increase local tumor control rates while keeping the radiation induced complications below desired thresholds. IMRT is currently widely introduced in clinical practice. However, the more complicated IMPT is still under development. Especially, spot-scanning techniques integrated in rotating gantries that can deliver proton or light ion-beams to a radiation target from any direction will be available in the near future. We describe the basic concepts of intensity modulated particle therapy (IMPT). Starting from the potential advantages of hadron therapy inverse treatment planning strategies are discussed for various dose delivery techniques of IMPT. Of special interest are the techniques of distal edge tracking (DET) and 3D-scanning. After the introduction of these concepts a study of comparative inverse treatment planning is presented. The study aims to identify the potential advantages of achievable physical dose distributions with proton and carbon beams, if different dose delivery techniques are employed. Moreover, a comparison to standard photon IMRT is performed. The results of the study are summarized as: i) IMRT with photon beams is a strong competitor to intensity modulated radiotherapy with charged particles. The most obvious benefit observed for charged particles is the reduction of medium and low doses in organs at risk. ii) The 3D-scanning technique could not improve the dosimetric results achieved with DET, although 10–15 times more beam spots were employed for 3D-scanning than for DET. However, concerns may arise about the application of DET, if positioning errors of the patient or organ movements have to be accounted for. iii) Replacing protons with carbon ions leads to further improvements of the physical dose distributions. However, the additional degree of improvement due to carbon ions is modest. The main clinical potential of heavy ion beams is probably related to their radiobiological properties.

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