Composite x-ray image assembly for large-field digital mammography with one- and two-dimensional positioning of a focal plane array

1998 ◽  
Vol 25 (2) ◽  
pp. 172-175 ◽  
Author(s):  
Gary Halama ◽  
James McAdoo ◽  
Hong Liu
Keyword(s):  
Digital Mammography ◽  
Focal Plane ◽  
Focal Plane Array ◽  
Large Field ◽  
Two Dimensional ◽  
X Ray

scholarly journals A 0.8-μm CMOS two-dimensional programmable mixed-signal focal-plane array processor with on-chip binary imaging and instructions storage

1997 ◽  
Vol 32 (7) ◽  
pp. 1013-1026 ◽  
Author(s):  
R. Dominguez-Castro ◽  
S. Espejo ◽  
A. Rodriguez-Vazquez ◽  
R.A. Carmona ◽  
P. Foldesy ◽  
...  
Keyword(s):  
Focal Plane ◽  
Focal Plane Array ◽  
Two Dimensional ◽  
Array Processor ◽  
Mixed Signal ◽  
On Chip

Extended focal-plane array development for the International X-ray Observatory

2009 ◽  
Author(s):  
Stephen J. Smith ◽  
Simon R. Bandler ◽  
Joern Beyer ◽  
James A. Chervenak ◽  
Dietmar Drung ◽  
...  
Keyword(s):  
Focal Plane ◽  
Focal Plane Array ◽  
X Ray

Large field of view X-ray microscopy with asymmetric bent crystals and a laboratory source

2015 ◽  
Vol 48 (3) ◽  
pp. 876-881 ◽  
Author(s):  
Cesar Cusatis
Keyword(s):  
Critical Angle ◽  
Field Of View ◽  
One Dimension ◽  
Large Field ◽  
Two Dimensional ◽  
Trade Off ◽  
X Ray ◽  
Laboratory Source ◽  
Edge Method ◽  
Bent Crystals

In microscopy, there is a trade-off between the magnification and a workable field of view (FOV). In this paper, bent asymmetric diffraction wafers were used with a conventional X-ray source to accept high divergence and increase the FOV of a two-dimensional X-ray microscope. An FOV of 5 mm with 20× magnification was realized with two independent wafers in a thermomechanically stable setup. Using the knife-edge method, a resolution of 2.5 µm was measured in one dimension. The FOV of such a system is limited by the sizes of the wafers, and the magnification is limited only by the critical angle of external reflection.

Tubulin structure at intermediate resolution

1995 ◽  
Vol 53 ◽  
pp. 852-853
Author(s):  
K. H. Downing ◽  
S. G. Wolf ◽  
E. Nogales
Keyword(s):  
High Resolution ◽  
Structural Data ◽  
Therapeutic Drug ◽  
Zinc Ions ◽  
Two Dimensional ◽  
X Ray Diffraction ◽  
X Ray ◽  
Negative Stain ◽  
Functional Mechanisms ◽  
Tubulin Structure

Microtubules are involved in a host of critical cell activities, many of which involve transport of organelles through the cell. Different sets of microtubules appear to form during the cell cycle for different functions. Knowledge of the structure of tubulin will be necessary in order to understand the various functional mechanisms of microtubule assemble, disassembly, and interaction with other molecules, but tubulin has so far resisted crystallization for x-ray diffraction studies. Fortuitously, in the presence of zinc ions, tubulin also forms two-dimensional, crystalline sheets that are ideally suited for study by electron microscopy. We have refined procedures for forming the sheets and preparing them for EM, and have been able to obtain high-resolution structural data that sheds light on the formation and stabilization of microtubules, and even the interaction with a therapeutic drug.Tubulin sheets had been extensively studied in negative stain, demonstrating that the same protofilament structure was formed in the sheets and microtubules. For high resolution studies, we have found that the sheets embedded in either glucose or tannin diffract to around 3 Å.

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