Recent Advances in Cancer Research: Cell Biology, Molecular Biology, and Tumor Virology , edited by R. C. Gallo

1980 ◽  
Vol 7 (2) ◽  
pp. 171-172
Author(s):  
Donald J. Pizzarello
Keyword(s):  
Cancer Research ◽  
Molecular Biology ◽  
Cell Biology ◽  
Recent Advances

Julian Lewis (1946–2014): A ‘serious hero’

2016 ◽  
Vol 26 (1) ◽  
pp. 33-37
Author(s):  
Heather Burton Raff
Keyword(s):  
Cancer Research ◽  
Molecular Biology ◽  
Cell Biology ◽  
Cell Communication ◽  
Embryonic Patterning ◽  
King's College ◽  
Medical Researcher ◽  
Biology Organization ◽  
Organization Membership ◽  
European Molecular Biology Organization

Julian Lewis was a gifted medical researcher and writer. His early background was the Classics; then Physics and Math; finally, Molecular Cell Biology. He worked on important questions in early embryonic patterning and the cell communication system, and so cancer research, at King’s College London, the Imperial Cancer Research Fund Oxford, and finally, Cancer Research UK London. He was a lifelong coauthor of the international textbook Molecular Biology of the Cell. His final personal battle with cancer was brave and not hidden. Awards included the Waddington Medal, a European Molecular Biology Organization membership, and a Fellowship of the Royal Society.

Recent Advances of Small Molecular Regulators Targeting G Protein- Coupled Receptors Family for Oncology Immunotherapy

2019 ◽  
Vol 19 (16) ◽  
pp. 1464-1483 ◽  
Author(s):  
Peng He ◽  
Wenbo Zhou ◽  
Mingyao Liu ◽  
Yihua Chen
Keyword(s):  
G Protein ◽  
Cell Biology ◽  
Immune Cell ◽  
G Protein Coupled Receptors ◽  
Treatment Modalities ◽  
Immune Checkpoints ◽  
Considerable Proportion ◽  
Prostaglandin E ◽  
Recent Advances ◽  
G Protein Coupled

The great clinical success of chimeric antigen receptor T cell (CAR-T) and PD-1/PDL-1 inhibitor therapies suggests the drawing of a cancer immunotherapy age. However, a considerable proportion of cancer patients currently receive little benefit from these treatment modalities, indicating that multiple immunosuppressive mechanisms exist in the tumor microenvironment. In this review, we mainly discuss recent advances in small molecular regulators targeting G Protein-Coupled Receptors (GPCRs) that are associated with oncology immunomodulation, including chemokine receptors, purinergic receptors, prostaglandin E receptor EP4 and opioid receptors. Moreover, we outline how they affect tumor immunity and neoplasia by regulating immune cell recruitment and modulating tumor stromal cell biology. We also summarize the data from recent clinical advances in small molecular regulators targeting these GPCRs, in combination with immune checkpoints blockers, such as PD-1/PDL-1 and CTLA4 inhibitors, for cancer treatments.

scholarly journals Carl Singer (1945-2013) – Life on a Plate: Yeast genetics meetings and micromanipulators

2021 ◽  
Author(s):  
Harry Singer ◽  
Terrance G Cooper
Keyword(s):  
Molecular Biology ◽  
Cell Biology ◽  
Cutting Edge ◽  
Genetic Maps ◽  
Yeast Genetics

Abstract Micromanipulators, more than any other instrument, opened the early doors to developing the powerful genetics of yeast that underlies much of the molecular work today. The ability to separate the spores of a tetrad and analyze their phenotypes generated the genetic maps and biology upon which subsequent cloning, sequencing, cutting edge molecular and cell biology depended. This work describes the development of those micromanipulators from garage to barn to factory and the developer of the sophisticated instruments we use today. For more than 30 years Carl Singer and his family were staunch and generous supporters of the International Conferences on Yeast Genetics and Molecular Biology meetings both in Europe and America. Carl Singer's displays at meetings became a traditional fixture and engaged the appetites of many students and advanced researchers to employ a technique that many perceived as too complicated or difficult, but which he made simple and easy to learn. His experiences also document a sketch of the international yeast meetings, their venues and how they developed through the years.

scholarly journals Evolution of Bioengineered Lung Models: Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology

2019 ◽  
Vol 29 (39) ◽  
pp. 1903114 ◽  
Author(s):  
Ali Doryab ◽  
Sinem Tas ◽  
Mehmet Berat Taskin ◽  
Lin Yang ◽  
Anne Hilgendorff ◽  
...  
Keyword(s):  
Cell Biology ◽  
Mechanical Forces ◽  
Recent Advances

scholarly journals Biotegnologie — ’n Nuwe benadering in planteteling

1991 ◽  
Vol 10 (1) ◽  
pp. 18-25
Author(s):  
D. I. Ferreira
Keyword(s):  
Tissue Culture ◽  
Molecular Biology ◽  
Plant Breeding ◽  
Cell Biology ◽  
Crop Production ◽  
Recombinant Dna ◽  
Global Approach ◽  
Recombinant Dna Technology ◽  
Half Century ◽  
Dna Technology

Conventional plant breeding has made a significant impact on the increase in crop production during the last half century. Several shortcomings however, opened up the opportunities for the application of biotechnology in plant breeding. The vari­ous approaches in the field of cell biology (tissue culture) and molecular biology (recombinant DNA technology) are dis­cussed and the application thereof is advocated in a global approach to plant breeding.

Recent advances in the molecular biology and physiology of nucleoside and nucleobase transporters

2001 ◽  
Vol 52 (1-2) ◽  
pp. 431-437 ◽  
Author(s):  
Mar�al Pastor-Anglada ◽  
Stephen A. Baldwin
Keyword(s):  
Molecular Biology ◽  
Recent Advances
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