SU-F-T-608: Forward Treatment Planning Techniques On Leksell Gamma Knife for the Normalization Effect Reduction

2016 ◽  
Vol 43 (6Part22) ◽  
pp. 3603-3603
Author(s):  
H Cheng ◽  
D Pan ◽  
J Tsai
Keyword(s):  
Treatment Planning ◽  
Gamma Knife ◽  
Planning Techniques ◽  
Normalization Effect

scholarly journals Forward treatment planning techniques to reduce the normalization effect in Gamma Knife radiosurgery

2017 ◽  
Vol 18 (6) ◽  
pp. 114-122
Author(s):  
Hao-Wen Cheng ◽  
Wei-Lun Lo ◽  
Chun-Yuan Kuo ◽  
Yu-Kai Su ◽  
Jo-Ting Tsai ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Planning Techniques ◽  
Normalization Effect

A simple treatment planning strategy for patients with multiple metastases treated with Gamma Knife surgery

2006 ◽  
Vol 105 (Supplement) ◽  
pp. 2-4 ◽  
Author(s):  
James G. Douglas ◽  
Robert Goodkin
Keyword(s):  
Mr Imaging ◽  
Treatment Planning ◽  
Gamma Knife ◽  
Gamma Knife Surgery ◽  
Planning Method ◽  
Cns Metastases ◽  
Cell Lung Carcinoma ◽  
Dose Volume Histograms ◽  
Number Of Patients ◽  
The Brain

ObjectIn a substantial number of patients treated at the authors' facility for brain metastases, additional lesions are identified at the time of Gamma Knife surgery (GKS). These lesions are often widely dispersed and may number over 10, which is the maximal number of matrices that can be currently placed for treatment with Leksell Gamma-Plan 4C. The authors describe a simple planning method for GKS in patients with multiple, widely dispersed central nervous system (CNS) metastases.MethodsTwo patients presented with three to five identified recurrent metastases from non–small cell lung carcinoma and breast carcinoma after having received whole-brain radiotherapy. At the time of treatment with GKS in each patient, spoiled-gradient Gd-enhanced magnetic resonance (MR) imaging revealed substantially more metastases than originally thought, which were widely scattered throughout all regions of the brain. The authors simplified the treatment planning approach by dividing the entire CNS contents into six contiguous, nonoverlapping matrices, which allowed for the planning, calculation, and treatment of all lesions.Two patients were successfully treated with GKS for more than 10 CNS metastases by using this simple planning method. Differing peripheral doses to varied-size lesions were delivered by prescribing to different isodose curves within any given matrix when required. Dose–volume histograms showed brain doses as follows: 10% of the total brain volume received 5 to 6.4 Gy; 25% received 3.8 to 4.8 Gy; 50% received 2.7 to 3.1 Gy; and 75% received 2.2 to 2.5 Gy.Conclusions The delineation of more metastases than appreciated on the diagnostic MR imaging is a common occurrence at the time of GKS at the authors' institution. The treatment of multiple (>10), widely dispersed CNS metastases can be simplified by the placement of multiple, contiguous, non-overlapping matrices, which can be employed to treat lesions in all areas of the brain when separate matrices cannot be utilized.

scholarly journals 111. Treatment planning in radiosurgery with GAMMA KNIFE : Accuracy & device useing CAG

1993 ◽  
Vol 49 (2) ◽  
pp. 231
Author(s):  
Eisaku Katoh ◽  
Rituo Satoh ◽  
Yoshihito Hagiwara ◽  
Norio senzui ◽  
Masami Gotoh ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Gamma Knife

Optic radiation tractography integrated into simulated treatment planning for Gamma Knife surgery

2007 ◽  
Vol 107 (4) ◽  
pp. 721-726 ◽  
Author(s):  
Keisuke Maruyama ◽  
Kyousuke Kamada ◽  
Masahiro Shin ◽  
Daisuke Itoh ◽  
Yoshitaka Masutani ◽  
...  
Keyword(s):  
Visual Field ◽  
Treatment Planning ◽  
Gamma Knife ◽  
Diffusion Tensor ◽  
Maximum Dose ◽  
Gamma Knife Surgery ◽  
Optic Radiation ◽  
Imaging Studies ◽  
Visual Field Deficits ◽  
Neurological Change

Object No definitive method of preventing visual field deficits after stereotactic radiosurgery for lesions near the optic radiation (OR) has been available so far. The authors report the results of integrating OR tractography based on diffusion tensor (DT) magnetic resonance imaging into simulated treatment planning for Gamma Knife surgery (GKS). Methods Data from imaging studies performed in 10 patients who underwent GKS for treatment of arteriovenous malformations (AVMs) located adjacent to the OR were used for the simulated treatment planning. Diffusion tensor images performed without the patient's head being secured by a stereotactic frame were used for DT tractography, and the OR was visualized by means of software developed by the authors. Data from stereotactic 3D imaging studies performed after frame fixation were coregistered with the data from DT tractography. The combined images were transferred to a GKS treatment-planning workstation. Delivered doses and distances between the treated lesions and the OR were analyzed and correlated with posttreatment neurological changes. Results In patients presenting with migraine with visual aura or occipital lobe epilepsy, the OR was located within 11 mm from AVMs. In a patient who developed new quadrantanopia after GKS, the OR had received 32 Gy. A maximum dose to the OR of less than 12 Gy did not cause new visual field deficits. A maximum dose to the OR of 8 Gy or more was significantly related to neurological change (p < 0.05), including visual field deficits and development or improvement of migraine. Conclusions Integration of OR tractography into GKS represents a promising tool for preventing GKS-induced visual disturbances and headaches. Single-session irradiation at a dose of 8 Gy or more was associated with neurological change.

SU-E-T-542: Impact of Convolution Algorithm Based Treatment Planning in Gamma Knife Radiosurgery

2013 ◽  
Vol 40 (6Part19) ◽  
pp. 330-330
Author(s):  
gopishankar natanasabapathi ◽  
Raj Kishor Bisht
Keyword(s):  
Treatment Planning ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Convolution Algorithm
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