SU-F-T-423: Automating Treatment Planning for Cervical Cancer in Low- and Middle- Income Countries

2016 ◽  
Vol 43 (6Part19) ◽  
pp. 3560-3560 ◽  
Author(s):  
K Kisling ◽  
L Zhang ◽  
J Yang ◽  
A Jhingran ◽  
P Balter ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Treatment Planning ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Implementation of Multicolor Melt Curve Analysis for High-Risk Human Papilloma Virus Detection in Low- and Middle-Income Countries: A Pilot Study for Expanded Cervical Cancer Screening in Honduras

2018 ◽  
pp. 1-8 ◽  
Author(s):  
Scott A. Turner ◽  
Sophie J. Deharvengt ◽  
Kathleen Doyle Lyons ◽  
Jorge Arturo Plata Espinal ◽  
Ethan P.M. LaRochelle ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
High Risk ◽  
Medical Center ◽  
Virus Detection ◽  
The United States ◽  
Middle Income ◽  
Rural Village ◽  
Middle Income Countries ◽  
Dartmouth Hitchcock Medical ◽  
Low And Middle Income

Purpose Cervical cancer is a leading cause of cancer-related mortality in low- and middle-income countries (LMICs) and screening in LMICs is extremely limited. We aimed to implement on-site high-risk human papillomavirus (hrHPV) DNA testing in cohorts of women from an urban factory and from a rural village. Methods A total of 802 women were recruited for this study in partnership with La Liga Contra el Cancer through the establishment of women’s health resource fairs at two locations in Honduras: a textile factory (n = 401) in the city of San Pedro Sula and the rural village of El Rosario (n = 401) in Yoro. Participants received a routine cervical examination during which three sterile cytobrushes were used to collect cervical samples for testing. hrHPV genotyping was performed using a hrHPV genotyping assay and a real-time polymerase chain reaction instrument. Results hrHPV status across all participants at both sites was 13% hrHPV positive and 67% hrHPV negative. When hrHPV status was compared across all three testing sites, hrHPV-positive rates were approximately equal among the factory (13%), village (12%), and confirmatory testing at Dartmouth-Hitchcock Medical Center (Lebanon, NH; 14%). hrHPV genotype was compared across sites, with HPV16 showing the highest infection rate (15%), followed by HPV59 (12%), and HPV68 (11%). There was a low prevalence of HPV18 observed in both populations compared with the hrHPV-positive population in the United States. Conclusion In collaboration with oncologists and pathologists from La Liga Contra el Cancer, we were able to provide a continuum of care once health-fair testing was performed. We established a method and implementation plan for hrHPV testing that is sustainable in LMICs.

scholarly journals Developing the Evidence Base to Inform Best Practice: A Scoping Study of Breast and Cervical Cancer Reviews in Low- and Middle-Income Countries

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0134618 ◽  
Author(s):  
Margaret M. Demment ◽  
Karen Peters ◽  
J. Andrew Dykens ◽  
Ann Dozier ◽  
Haq Nawaz ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Best Practice ◽  
Evidence Base ◽  
Middle Income ◽  
Scoping Study ◽  
Middle Income Countries ◽  
Breast And Cervical Cancer ◽  
Low And Middle Income

scholarly journals Morbidity after surgical management of cervical cancer in low and middle income countries: A systematic review and meta-analysis

PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0217775
Author(s):  
Emma R. Allanson ◽  
Aime Powell ◽  
Max Bulsara ◽  
Hong Lim Lee ◽  
Lynette Denny ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Surgical Management ◽  
Meta Analysis ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Meeting the emerging challenge of breast and cervical cancer in low- and middle-income countries

2012 ◽  
Vol 119 ◽  
pp. S85-S88 ◽  
Author(s):  
Felicia M. Knaul ◽  
Afsan Bhadelia ◽  
Julie Gralow ◽  
Héctor Arreola-Ornelas ◽  
Ana Langer ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Middle Income ◽  
Middle Income Countries ◽  
Breast And Cervical Cancer ◽  
Low And Middle Income

Incidence, Treatment and Outcomes of Cervical Cancer in Low- and Middle-income Countries

2021 ◽  
Author(s):  
U. Mahantshetty ◽  
G. Lavanya ◽  
S. Grover ◽  
C.A. Akinfenwa ◽  
H. Carvalho ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Clinical trial to implementation: Cost and effectiveness considerations for scaling up cervical cancer screening in low- and middle-income countries

2016 ◽  
Vol 7 ◽  
pp. 4-11 ◽  
Author(s):  
Sujha Subramanian ◽  
Rengaswamy Sankaranarayanan ◽  
Pulikkottil Okkuru Esmy ◽  
Jissa Vinoda Thulaseedharan ◽  
Rajaraman Swaminathan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Scaling Up ◽  
Implementation Cost ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Impact of High-Dose-Rate Brachytherapy Training via Telehealth in Low- and Middle-Income Countries

2020 ◽  
pp. 1803-1812
Author(s):  
Jeremy B. Hatcher ◽  
Oluwadamilola Oladeru ◽  
Betty Chang ◽  
Sameeksha Malhotra ◽  
Megan Mcleod ◽  
...  
Keyword(s):  
Dose Rate ◽  
Treatment Planning ◽  
High Dose Rate ◽  
High Dose ◽  
Hdr Brachytherapy ◽  
Middle Income ◽  
Middle Income Countries ◽  
Radiation Oncologists ◽  
Medical Physicists ◽  
Low And Middle Income

PURPOSE Our objective was to demonstrate the efficacy of a telehealth training course on high-dose-rate (HDR) brachytherapy for gynecologic cancer treatment for clinicians in low- and middle-income countries (LMICs) METHODS A 12-week course consisting of 16 live video sessions was offered to 10 cancer centers in the Middle East, Africa, and Nepal. A total of 46 participants joined the course, and 22 participants, on average, attended each session. Radiation oncologists and medical physicists from 11 US and international institutions prepared and provided lectures for each topic covered in the course. Confidence surveys of 15 practical competencies were administered to participants before and after the course. Competencies focused on HDR commissioning, shielding, treatment planning, radiobiology, and applicators. Pre- and post-program surveys of provider confidence, measured by 5-point Likert scale, were administered and compared. RESULTS Forty-six participants, including seven chief medical physicists, 16 senior medical physicists, five radiation oncologists, and three dosimetrists, representing nine countries attended education sessions. Reported confidence scores, both aggregate and paired, demonstrated increases in confidence in all 15 competencies. Post-curriculum score improvement was statistically significant ( P < .05) for paired respondents in 11 of 15 domains. Absolute improvements were largest for confidence in applicator commissioning (2.3 to 3.8, P = .009), treatment planning system commissioning (2.2 to 3.9, P = .0055), and commissioning an HDR machine (2.2 to 4.0, P = .0031). Overall confidence in providing HDR brachytherapy services safely and teaching other providers increased from 3.1 to 3.8 and 3.0 to 3.5, respectively. CONCLUSION A 12-week, low-cost telehealth training program on HDR brachytherapy improved confidence in treatment delivery and teaching for clinicians in 10 participating LMICs.

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