SU-F-J-127: Multi-Institutional Evaluation of Setup, Organ Deformation, Precision Dosimetry in Total Marrow Irradiation

2016 ◽  
Vol 43 (6Part10) ◽  
pp. 3436-3436
Author(s):  
D Zuro ◽  
S Hui
Author(s):  
Bob Blankenberger ◽  
Sophia Gehlhausen Anderson ◽  
Eric Lichtenberger

A correction to this paper has been published: https://doi.org/10.1007/s11162-021-09646-8


1984 ◽  
Vol 2 (1) ◽  
pp. 12-32 ◽  
Author(s):  
James M. Buchanan ◽  
Loren E. Lomasky

There are no first principles etched in stone from which all moral philosophers must take their bearings. We must deliberately choose our point of departure in any attempt to respond to the question: “Must any defensible theory of justice incorporate both a commitment to personal liberty and to economic equality?” Basic to our own approach is a suspicion of seers and visionaries who espy an external source of values independent from human choices. We presuppose, instead, that political philosophy commences with individual evaluation.1 A near-corollary of this presupposition is that each individual's preferences ought to be taken into account equally with those of others. That is, we suppose that there is no privileged evaluator, whose preferences are accorded decisive weight. Conceptual unanimity as a criterion for institutional evaluation follows naturally from the other two presuppositions. If there is neither an external standard of value nor a corps of resident value experts, only unanimity can ultimately be satisfactory as a test of social desirability. Our perspective then is subjectivist, individualist, and unanimitarian.These presuppositions inform our contractarian analysis. There are, however, two separate contractarian traditions that we shall find useful to distinguish, the “Hobbesian” and the “Rawlsian.” In the first, persons find themselves in the anarchistic war of each against all. They contract away their natural liberties in exchange for the order that civil society – through its sovereign – affords. In this contracting process, individuals are assumed to possess full self-knowledge; they know who they are, what conceptions of the good they hold, and what their endowments are.


2017 ◽  
Vol 85 (5) ◽  
pp. AB540
Author(s):  
Marc F. Catalano ◽  
Naser M. Khan ◽  
Michael Lajin ◽  
Shahid Ali ◽  
Joseph B. Henderson

Urology ◽  
2001 ◽  
Vol 57 (3) ◽  
pp. 491-494 ◽  
Author(s):  
Patrick C Walsh ◽  
Penny Marschke ◽  
William J Catalona ◽  
Herbert Lepor ◽  
Sighle Martin ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Luping Zheng ◽  
Jinai Yao ◽  
Fangluan Gao ◽  
Lin Chen ◽  
Chao Zhang ◽  
...  

Nucleolar proteins play important roles in plant cytology, growth, and development. Fibrillarin2 is a nucleolar protein ofNicotiana benthamiana(N. benthamiana). Its cDNA was amplified by RT-PCR and inserted into expression vector pEarley101 labeled with yellow fluorescent protein (YFP). The fusion protein was localized in the nucleolus and Cajal body of leaf epidermal cells ofN. benthamiana. TheN. benthamianafibrillarin2 (NbFib2) protein has three functional domains (i.e., glycine and arginine rich domain, RNA-binding domain, andα-helical domain) and a nuclear localization signal (NLS) in C-terminal. The protein 3D structure analysis predicted that NbFib2 is anα/βprotein. In addition, the virus induced gene silencing (VIGS) approach was used to determine the function of NbFib2. Our results showed that symptoms including growth retardation, organ deformation, chlorosis, and necrosis appeared in NbFib2-silencedN. benthamiana.


Cancers ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1709 ◽  
Author(s):  
Curto ◽  
Aklan ◽  
Mulder ◽  
Mils ◽  
Schmidt ◽  
...  

Clinical outcome of hyperthermia depends on the achieved target temperature, therefore target conformal heating is essential. Currently, invasive temperature probe measurements are the gold standard for temperature monitoring, however, they only provide limited sparse data. In contrast, magnetic resonance thermometry (MRT) provides unique capabilities to non-invasively measure the 3D-temperature. This study investigates MRT accuracy for MR-hyperthermia hybrid systems located at five European institutions while heating a centric or eccentric target in anthropomorphic phantoms with pelvic and spine structures. Scatter plots, root mean square error (RMSE) and Bland–Altman analysis were used to quantify accuracy of MRT compared to high resistance thermistor probe measurements. For all institutions, a linear relation between MRT and thermistor probes measurements was found with R2 (mean ± standard deviation) of 0.97 ± 0.03 and 0.97 ± 0.02, respectively for centric and eccentric heating targets. The RMSE was found to be 0.52 ± 0.31 °C and 0.30 ± 0.20 °C, respectively. The Bland-Altman evaluation showed a mean difference of 0.46 ± 0.20 °C and 0.13 ± 0.08 °C, respectively. This first multi-institutional evaluation of MR-hyperthermia hybrid systems indicates comparable device performance and good agreement between MRT and thermistor probes measurements. This forms the basis to standardize treatments in multi-institution studies of MR-guided hyperthermia and to elucidate thermal dose-effect relations.


2010 ◽  
Vol 184 (3) ◽  
pp. 1223-1224
Author(s):  
B.E. Ayres ◽  
S.R.J. Bott ◽  
N.J. Barber ◽  
S.E.M. Langley ◽  
B.S.I. Montgomery

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