scholarly journals Characterization of trabecular bone plate-rod microarchitecture using multirow detector CT and the tensor scale: Algorithms, validation, and applications to pilot human studies

2015 ◽  
Vol 42 (9) ◽  
pp. 5410-5425 ◽  
Author(s):  
Punam K. Saha ◽  
Yinxiao Liu ◽  
Cheng Chen ◽  
Dakai Jin ◽  
Elena M. Letuchy ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Human Studies ◽  
Bone Plate ◽  
Tensor Scale ◽  
Multirow Detector Ct

Characterization of in vitro leukocyte maximal telomerase activity capacity (mTAC) as a stress-related measure for human studies

2017 ◽  
Vol 83 ◽  
pp. 51
Author(s):  
Karin de Punder ◽  
Christine Heim ◽  
Ingo Przesdzing ◽  
Pathik D. Wadhwa ◽  
Sonja Entringer
Keyword(s):  
Telomerase Activity ◽  
Human Studies ◽  
Related Measure

Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone

2015 ◽  
Vol 137 (1) ◽  
Author(s):  
Alexander Zwahlen ◽  
David Christen ◽  
Davide Ruffoni ◽  
Philipp Schneider ◽  
Werner Schmölz ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Bone Structure ◽  
Experimental Studies ◽  
Tissue Level ◽  
Heterogeneous Distribution ◽  
Human Trabecular Bone ◽  
Young’S Moduli ◽  
Failure Assessment ◽  
Experimental Strain

The local interpretation of microfinite element (μFE) simulations plays a pivotal role for studying bone structure–function relationships such as failure processes and bone remodeling. In the past μFE simulations have been successfully validated on the apparent level, however, at the tissue level validations are sparse and less promising. Furthermore, intratrabecular heterogeneity of the material properties has been shown by experimental studies. We proposed an inverse μFE algorithm that iteratively changes the tissue level Young’s moduli such that the μFE simulation matches the experimental strain measurements. The algorithm is setup as a feedback loop where the modulus is iteratively adapted until the simulated strain matches the experimental strain. The experimental strain of human trabecular bone specimens was calculated from time-lapsed images that were gained by combining mechanical testing and synchrotron radiation microcomputed tomography (SRμCT). The inverse μFE algorithm was able to iterate the heterogeneous distribution of moduli such that the resulting μFE simulations matched artificially generated and experimentally measured strains.

Dehydration and Rehydration Alter Elastic and Viscoelastic Nanomechanical Properties of Cortical and Trabecular Bone

2010 ◽  
Author(s):  
Suzanne Ferreri ◽  
Bing Hu ◽  
Yi-Xian Qin
Keyword(s):  
Trabecular Bone ◽  
Elastic Properties ◽  
Mechanical Loading ◽  
Bone Mineral ◽  
Viscoelastic Properties ◽  
Therapeutic Interventions ◽  
Critical Importance ◽  
Nanomechanical Properties

Evaluation of bone’s response to mechanical loading is of critical importance in studies addressing the overall efficacy of therapeutic interventions. Moreover, thorough characterization of bone’s response to applied loads should reflect the contributions of both bone mineral (elastic properties) and collagen (viscoelastic properties).

Structural and Radiological Parameters for the Nondestructive Characterization of Trabecular Bone

2001 ◽  
Vol 29 (12) ◽  
pp. 1064-1073 ◽  
Author(s):  
V. Pattijn ◽  
T. Van Cleynenbreugel ◽  
J. Vander Sloten ◽  
R. Van Audekercke ◽  
G. Van der Perre ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Radiological Parameters ◽  
Nondestructive Characterization

Predicting mechanical competence of trabecular bone using 3D tensor-scale-based parameters

2005 ◽  
Author(s):  
Punam K. Saha ◽  
Michael J. Wald ◽  
Alex Radin ◽  
Felix W. Wehrli
Keyword(s):  
Trabecular Bone ◽  
Tensor Scale
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