scholarly journals Validation of an in-vivo proton beam range check method in an anthropomorphic pelvic phantom using dose measurements

2015 ◽  
Vol 42 (4) ◽  
pp. 1936-1947 ◽  
Author(s):  
El H. Bentefour ◽  
Shikui Tang ◽  
Ethan W. Cascio ◽  
Mauro Testa ◽  
Deepak Samuel ◽  
...  
2009 ◽  
Vol 36 (6Part24) ◽  
pp. 2760-2760
Author(s):  
MF Gensheimer ◽  
TI Yock ◽  
NJ Liebsch ◽  
GC Sharp ◽  
N Madan ◽  
...  

2010 ◽  
Vol 78 (1) ◽  
pp. 268-275 ◽  
Author(s):  
Michael F. Gensheimer ◽  
Torunn I. Yock ◽  
Norbert J. Liebsch ◽  
Gregory C. Sharp ◽  
Harald Paganetti ◽  
...  

2010 ◽  
Vol 37 (6Part11) ◽  
pp. 3180-3180 ◽  
Author(s):  
S España ◽  
X Zhu ◽  
J Daartz ◽  
N Liebsch ◽  
G El Fakhri ◽  
...  

2021 ◽  
Author(s):  
Jerimy Polf ◽  
Carlos A. Barajas ◽  
Gerson C. Kroiz ◽  
Stephen W. Peterson ◽  
Paul Maggi ◽  
...  

Abstract We present Compton camera (CC) based PG imaging for proton range verification at clinical dose rates. PG emission from a tissue-equivalent phantom during irradiation with clinical proton beams was measured with a prototype CC. Images were reconstructed of the raw measured data and of data processed with a neural network (NN) trained to identify “true” and “false” PG events. From these images, we determine if PG images produced by the prototype CC could provide clinically useful information about the in vivo range of the proton beams delivered during proton beam radiotherapy. NN processing of the data was found necessary to allow identification of the proton beam path from the PG images. Furthermore, to allow the localization of the end of the proton beam range with a precision of ≤ 3mm with the prototype CC, ~1 x 109 protons would need to be delivered, which is on the order of magnitude delivered for a standard proton radiotherapy treatment field. To obtain higher precision in beam range determination and to allow imaging a single proton pencil beam delivered within the full treatment field, further improvements in PG detection rates by the CC, NN data processing, and image reconstruction algorithms are needed.


2017 ◽  
Vol 106 ◽  
pp. 644-649 ◽  
Author(s):  
S.O. Souza ◽  
F. d'Errico ◽  
B. Azimi ◽  
A. Baldassare ◽  
A.V.S. Alves ◽  
...  

Author(s):  
N Singh ◽  
Sh Ahamed ◽  
A Sinha ◽  
Sh Srivastava ◽  
N K Painuly ◽  
...  

Background: Intracavitary brachytherapy plays a major role in management of cervical carcinoma. Assessment of dose received by OAR’s therefore becomes crucial for the estimation of radiation toxicities in high dose rate brachytherapy.Objective: The purpose of this study is to evaluate the role of in vivo dosimetry in HDR brachytherapy and to compare the actual doses delivered to OAR’s with those calculated during treatment planning.Materials and Methods: A total of 50 patients were treated with Microselectron HDR. Out of 50 patients, 26 were treated with a dose of 7 Gy and 24 with a dose of 9 Gy, prescribed to point A. Brachytherapy planning and evaluation of dose to the bladder and rectum was done on TPS & in vivo dosimetry was performed using portable MOSFET.Results: The calibration factors calculated for both the dosimeters are almost equal and are 0.984 cGy/mV and 1.0895 cGy/mV. For bladder, dose deviation was found to be within +/- 5% in 28 patients, +/- 5-10% in 14 patients, +/- 10-15% in 4 patients. The deviation between the TPS-calculated dose and the dose measured by MOSFET for rectum was within +/- 5% in 31 patients, +/- 5–10% in 8 patients, and +/- 10–15% in 7 patients.Conclusion: TPS calculated doses were slightly higher than that measured by MOSFET. The use of a small size of MOSFET dosimeter is an efficient method for accurately measuring doses in high-dose gradient fields typically seen in brachytherapy. Therefore, to reduce risk of large errors in the dose delivery, in vivo dosimetry can be done in addition to TPS computations.


2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.


2004 ◽  
Vol 4 (4) ◽  
pp. 143-154 ◽  
Author(s):  
R. Appleyard ◽  
K. Ball ◽  
F. E. Hughes ◽  
W. Kilby ◽  
R. Nicholls ◽  
...  

Purpose: Having previously reviewed the implementation of systematic in vivo dosimetry at the Norfolk and Norwich Hospital this paper examines the results of entrance dose measurements for specific sites/techniques and determines whether different action/alert protocols are required for these different categories.Methods and materials: Entrance dose measurements using p-type diodes were analysed for the following treatment categories: Breast, head and neck in beam direction shell, abdomino-pelvic and intrathoracic. A 4% tolerance was applied.Results: Mean deviations from expected dose and proportion of measurements exceeding tolerance were: Breast: +1.15%±3.04% (1SD), 238/1073≥4%; Head and neck: +0.35%±2.20% (1SD), 21/326≥4%; Abdomino-pelvic: +0.52%±2.75% (1SD), 93/712≥4%; Intrathoracic: −0.01%±2.75% (1SD), 22/119≥4%. Significant improvements in results for breast patients were noted following the introduction of a commercial breast board. The results for abdomino-pelvic patients confirmed a substantial variation in diode response under short FSD, wedged fields at 16MV (that had not been corrected for). The statistical uncertainty in dose measurement for each treatment category was calculated in order to assist determination of appropriate tolerance levels.Conclusions: A blanket tolerance of 4% was generally too low given the extent of measurement uncertainty. The relatively high number of readings outside tolerance where identification of errors was difficult/impossible resulted in inconsistent application of the action protocol. Some widening of tolerances is likely to improve quality of procedure and treatment. Appropriate action levels are recommended for each treatment category.


2019 ◽  
Vol 51 (2) ◽  
pp. 533-538 ◽  
Author(s):  
Jong Hoon Park ◽  
Sung Hun Kim ◽  
Youngmo Ku ◽  
Hyun Su Lee ◽  
Chan Hyeong Kim ◽  
...  

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