A method of surface marker location optimization for tumor motion estimation in lung stereotactic body radiation therapy

2014 ◽  
Vol 42 (1) ◽  
pp. 244-253 ◽  
Author(s):  
Bo Lu ◽  
Yunmei Chen ◽  
Justin C. Park ◽  
Qiyong Fan ◽  
Darren Kahler ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Motion Estimation ◽  
Stereotactic Body Radiation Therapy ◽  
Surface Marker ◽  
Tumor Motion ◽  
Location Optimization ◽  
Stereotactic Body Radiation ◽  
Marker Location

Impact of lung tumor motion on dose delivered to organ at risk in lung stereotactic body radiation therapy

2020 ◽  
Vol 9 (3-4) ◽  
pp. 191-198
Author(s):  
Milovan Savanovic ◽  
Bojan Strbac ◽  
Drazan Jaros ◽  
Dejan Cazic ◽  
Jean Noel Foulquier
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Lung Tumor ◽  
Tumor Motion ◽  
Stereotactic Body Radiation ◽  
Organ At Risk

Stereotactic body radiation therapy for pancreatic cancer: Assessing motion with and without abdominal compression.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 234-234 ◽  
Author(s):  
Priscilla K. Stumpf ◽  
Bernard Jones ◽  
Supriya K. Jain ◽  
Arya Amini ◽  
Dale A. Thornton ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Organs At Risk ◽  
Locally Advanced ◽  
Advanced Pancreatic Cancer ◽  
Free Breathing ◽  
Tumor Motion ◽  
Abdominal Compression ◽  
Stereotactic Body Radiation

234 Background: Stereotactic body radiation therapy (SBRT) is an emerging treatment option for locally advanced pancreatic cancer. This ablative therapy requires highly accurate delivery due to nearby organs at risk. To minimize tumor motion, our institution applies abdominal compression during computed tomography (CT) simulation. The purpose of this study is to evaluate the effect of compression in the context of pancreatic SBRT. Methods: In the last 6 months, 32 patients who completed SBRT to the pancreas at our institution were selected for analysis. In each patient, two 4DCT images were acquired, one with and one without abdominal compression. Abdominal compression was achieved with an indexed compression belt with a customized degree of inflation. Each patient had fiducial markers implanted in or near the pancreatic tumor prior to simulation. These fiducials were contoured on both planning CT scans for each gated phase. Motion was assessed by fiducial position changes throughout each gated phase. Results: In the anterior to posterior, transverse, and superior to inferior dimension, compression decreased motion in 19 of 32 cases (59%), 21 of 32 cases (66%), and 28 of 32 cases (88%) respectively. In the anterior to posterior (AP) dimension compression decreased motion by a mean of 0.43mm ± 1.7mm with a range of -2.1-6.5mm (p = 0.16). The mean decrease in motion with compression in the transverse dimension was 0.93mm ± 1.9mm with a range of -1.6-8.6mm (p = 0.01). In the superior to inferior dimension, compression decreased motion by a mean of 2.72mm ± 2.8mm with a range of -1.2-11.5mm (p < 0.001). Displacement of tissue due to compression led to increased patient AP separation at the level of T12 by a mean of 9.1±5.8mm (p < 0.001). Conclusions: Abdominal compression significantly reduced tumor motion in the superior to inferior and transverse directions for patients undergoing SBRT to the pancreas. This decrease in motion allows for significant reductions in the size of the volume necessary to treat the tumor. Given our findings, we would recommend using abdominal compression over free-breathing for pancreatic SBRT.

scholarly journals The assessment of consecutive 4D-CT scans during simulation for lung stereotactic body radiation therapy patients

2020 ◽  
Vol 26 (4) ◽  
pp. 193-199
Author(s):  
Milovan Savanovic ◽  
Bojan Strbac ◽  
Drazan Jaros ◽  
Jean-Noel Foulquier
Keyword(s):  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Patient Positioning ◽  
Ct Scans ◽  
Tumor Motion ◽  
Initial Shape ◽  
4D Ct ◽  
Stereotactic Body Radiation ◽  
Breathing Period ◽  
The Impact

AbstractPurpose: To evaluate the breathing amplitude, tumor motion, patient positioning, and treatment volumes among consecutive four-dimensional computed tomography (4D-CT) scans, during the simulation for lung stereotactic body radiation therapy (SBRT).Material and methods: The variation and shape of the breathing amplitude, patient positioning, and treatment volumes were evaluated for 55 lung cancer patients after consecutive 4D-CT acquisitions, scanned at one-week intervals. The impact of variation in the breathing amplitude on lung tumor motion was determined for 20 patients. The gross tumor volume (GTV) was contoured from a free-breathing CT scan and at ten phases of the respiratory cycle, for both 4D-CTs (440 phases in total).Results: Breathing amplitude decreased by 3.6 (3.4-4.9) mm, tumor motion by 3.2 (0.4-5.0) mm while breathing period increased by 4 (2-6) s, inter-scan for 20 patients. Intra-scan variation was 4 times greater for the breathing amplitude, 5 times for the breathing period, and 8 times for the breathing cycle, comparing irregular versus regular breathing patterns for 55 patients. Using coaching, the breathing amplitude increases 3 to 8 mm, and the breathing period 2 to 6 s. Differences in the contoured treatment volumes were less than 10% between consecutive scans. Patient positioning remained stable, with a small inter-scan difference of 1.1 (0.6-1.4) mm.Conclusion: Decreasing the inter-scan breathing amplitude decreases the tumor motion reciprocally. When the breathing amplitude decreases, the breathing period increases at inter- and intra-scan, especially during irregular breathing. Coaching improves respiration, keeping the initial shape of the breathing amplitude. Contoured treatment volumes and patient positioning were reproducible through successive scans.

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