TH-A-19A-11: Validation of GPU-Based Monte Carlo Code (gPMC) Versus Fully Implemented Monte Carlo Code (TOPAS) for Proton Radiation Therapy: Clinical Cases Study

2014 ◽  
Vol 41 (6Part31) ◽  
pp. 535-535
Author(s):  
D Giantsoudi ◽  
J Schuemann ◽  
S Dowdell ◽  
X Jia ◽  
S Jiang ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Radiation Therapy ◽  
Monte Carlo Code ◽  
Proton Radiation ◽  
Proton Radiation Therapy ◽  
Cases Study ◽  
Clinical Cases

scholarly journals Validation of a GPU-based Monte Carlo code (gPMC) for proton radiation therapy: clinical cases study

2015 ◽  
Vol 60 (6) ◽  
pp. 2257-2269 ◽  
Author(s):  
Drosoula Giantsoudi ◽  
Jan Schuemann ◽  
Xun Jia ◽  
Stephen Dowdell ◽  
Steve Jiang ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Radiation Therapy ◽  
Monte Carlo Code ◽  
Proton Radiation ◽  
Proton Radiation Therapy ◽  
Cases Study ◽  
Clinical Cases

scholarly journals A comparative study on dispersed doses during photon and proton radiation therapy in pediatric applications

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248300
Author(s):  
Mehrdad Shahmohammadi Beni ◽  
Dragana Krstic ◽  
Dragoslav Nikezic ◽  
Kwan Ngok Yu
Keyword(s):  
Monte Carlo ◽  
Radiation Therapy ◽  
National Laboratory ◽  
Left Lung ◽  
Photon Radiation ◽  
Track Length ◽  
Proton Radiation ◽  
Oak Ridge ◽  
Proton Radiation Therapy ◽  
Pediatric Cancer Patients

The Monte Carlo method was employed to simulate realistic treatment situations for photon and proton radiation therapy for a set of Oak Ridge National Laboratory (ORNL) pediatric phantoms for 15, 10, 5 and 1-year olds as well as newborns. Complete radiotherapy situations were simulated using the previously developed NRUrad input code for Monte Carlo N-Particle (MCNP) code package. Each pediatric phantom was irradiated at five different positions, namely, the testes, colon, liver, left lung and brain, and the doses in targeted organs (Dt) were determined using the track length estimate of energy. The dispersed photon and proton doses in non-targeted organs (Dd), namely, the skeleton, skin, brain, spine, left and right lungs were computed. The conversion coefficients (F = Dd/Dt) of the dispersed doses were used to study the dose dispersion in different non-targeted organs for phantoms for 15, 10, 5 and 1-year olds as well as newborns. In general, the F values were larger for younger patients. The F values for non-targeted organs for phantoms for 1-year olds and newborns were significantly larger compared to those for other phantoms. The dispersed doses from proton radiation therapy were also found to be significantly lower than those from conventional photon radiation therapy. For example, the largest F values for the brain were 65.6% and 0.206% of the dose delivered to the left lung (P4) for newborns during photon and proton radiation therapy, respectively. The present results demonstrated that dispersion of photons and generated electrons significantly affected the absorbed doses in non-targeted organs during pediatric photon therapy, and illustrated that proton therapy could in general bring benefits for treatment of pediatric cancer patients.

Single Room Proton Radiation Therapy

2012 ◽  
Vol 84 (3) ◽  
pp. S835-S836
Author(s):  
E.E. Klein ◽  
C. Block ◽  
B. Pierburg ◽  
J. Bradley
Keyword(s):  
Radiation Therapy ◽  
Proton Radiation ◽  
Proton Radiation Therapy ◽  
Single Room
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