SU-E-J-19: Accuracy of Dual-Energy CT-Derived Relative Electron Density for Proton Therapy Dose Calculation

2014 ◽  
Vol 41 (6Part6) ◽  
pp. 158-159
Author(s):  
J Mullins ◽  
M Bues ◽  
X Duan ◽  
J Kruse ◽  
M Herman
Keyword(s):  
Electron Density ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Relative Electron Density ◽  
Relative Electron

scholarly journals EP-2085: Simplification of relative electron density information in synthetic CT images for dose calculation

2018 ◽  
Vol 127 ◽  
pp. S1144-S1145
Author(s):  
J. Handrack ◽  
M. Bangert ◽  
C. Möhler ◽  
T. Bostel ◽  
S. Greilich
Keyword(s):  
Electron Density ◽  
Dose Calculation ◽  
Ct Images ◽  
Relative Electron Density ◽  
Relative Electron ◽  
Synthetic Ct

scholarly journals Feasibility of using post-contrast dual-energy CT for pediatric radiation treatment planning and dose calculation

2020 ◽  
pp. 20200170
Author(s):  
Ozgur Ates ◽  
Chia-ho Hua ◽  
Li Zhao ◽  
Nadav Shapira ◽  
Yoad Yagil ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Dose Calculation ◽  
Iodine Concentration ◽  
Dual Energy ◽  
Conventional Approach ◽  
Dual Energy Ct ◽  
Post Contrast ◽  
Dose Distributions ◽  
Iodinated Contrast ◽  
Contrast Ct

Objectives: When iodinated contrast is administered during CT simulation, standard practice requires a separate non-contrast CT for dose calculation. The objective of this study is to validate our hypothesis that since iodine affects Hounsfield units (HUs) more than electron density (ED), the information from post-contrast dual-layer CT (DLCT) would be sufficient for accurate dose calculation for both photon and proton therapy. Methods and materials: 10 pediatric patients with abdominal tumors underwent DLCT scans before and after iodinated contrast administration for radiotherapy planning. Dose distributions with these DLCT-based methods were compared to those with conventional calibration-curve methods that map HU images to ED and stopping-power ratio (SPR) images. Results: For photon plans, conventional and DLCT approaches based on post-contrast scans underestimated the PTV D99 by 0.87 ± 0.70% (p = 0.18) and 0.36 ± 0.31% (p = 0.34), respectively, comparing to their non-contrast optimization plans. Renal iodine concentration was weakly associated with D99 deviation for both conventional (R2 = 0.10) and DLCT (R2 = 0.02) approaches. For proton plans, the clinical target volume D99 errors were 3.67 ± 2.43% (p = 0.0001) and 0.30 ± 0.25% (p = 0.40) for conventional and DLCT approaches, respectively. The proton beam range changed noticeably with the conventional approach. Renal iodine concentration was highly associated with D99 deviation for the conventional approach (R2 = 0.83) but not for DLCT (R2 = 0.007). Conclusion: Conventional CT with iodine contrast resulted in a large dosimetric error for proton therapy, compared to true non-contrast plans, but the error was less for photon therapy. These errors can be greatly reduced in the case of the proton plans if DLCT is used, raising the possibility of using only a single post-contrast CT for radiotherapy dose calculation, thus reducing the time and imaging dose required. Advances in knowledge: This study is the first to compare directly the differences in the calculated dose distributions between pre- and post-contrast CT images generated by single-energy CT and dual-energy CT methods for photon and proton therapy.

Influence of intravenous contrast agent on dose calculation in proton therapy using dual energy CT

2019 ◽  
Vol 64 (12) ◽  
pp. 125024 ◽  
Author(s):  
Arthur Lalonde ◽  
Yunhe Xie ◽  
Brendan Burgdorf ◽  
Shannon O’Reilly ◽  
William Scott Ingram ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Intravenous Contrast ◽  
Intravenous Contrast Agent

scholarly journals PO-0871: Relative electron density determination for radiotherapy and proton therapy treatment planning

2015 ◽  
Vol 115 ◽  
pp. S444-S445
Author(s):  
J.K. Van Abbema ◽  
M. Van Goethem ◽  
M.J.W. Greuter ◽  
A. Van der Schaaf ◽  
S. Brandenburg ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Electron Density ◽  
Proton Therapy ◽  
Density Determination ◽  
Relative Electron Density ◽  
Relative Electron ◽  
Therapy Treatment

scholarly journals CT-guided bone biopsy using electron density maps from dual-energy CT

2021 ◽  
Vol 16 (9) ◽  
pp. 2343-2346
Author(s):  
Shota Yamamoto ◽  
Shunsuke Kamei ◽  
Kosuke Tomita ◽  
Chikara Fujita ◽  
Kazuyuki Endo ◽  
...  
Keyword(s):  
Electron Density ◽  
Bone Biopsy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Ct Guided ◽  
Density Maps
Sign in / Sign up

Export Citation Format

Share Document