scholarly journals The potential of positron emission tomography for intratreatment dynamic lung tumor tracking: A phantom study

2014 ◽  
Vol 41 (2) ◽  
pp. 021718 ◽  
Author(s):  
Jaewon Yang ◽  
Tokihiro Yamamoto ◽  
Samuel R. Mazin ◽  
Edward E. Graves ◽  
Paul J. Keall
Keyword(s):  
Positron Emission Tomography ◽  
Lung Tumor ◽  
Phantom Study ◽  
Emission Tomography ◽  
Tumor Tracking ◽  
Positron Emission

scholarly journals Value of integrated positron emission tomography revised using a phantom study to evaluate malignancy grade of lung adenocarcinoma

Cancer ◽  
2010 ◽  
Vol 116 (13) ◽  
pp. 3170-3177 ◽  
Author(s):  
Haruhiko Nakayama ◽  
Sakae Okumura ◽  
Hiromitsu Daisaki ◽  
Yasufumi Kato ◽  
Hirofumi Uehara ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Lung Adenocarcinoma ◽  
Phantom Study ◽  
Emission Tomography ◽  
Malignancy Grade ◽  
Positron Emission

scholarly journals Evaluation of image quality at the detector’s edge of dedicated breast positron emission tomography

2020 ◽  
Author(s):  
Yoko Satoh ◽  
Utaroh Motosugi ◽  
Masamichi Imai ◽  
Yoshie Omiya ◽  
Hiroshi Onishi
Keyword(s):  
Positron Emission Tomography ◽  
Image Quality ◽  
Chest Wall ◽  
Clinical Studies ◽  
Phantom Study ◽  
Emission Tomography ◽  
Breast Lesions ◽  
Clinical Images ◽  
Positron Emission ◽  
Pet Ct

Abstract Background: The dedicated breast positron emission tomography (dbPET) scanner (Elmamo, Shimadzu, Kyoto, Japan) has received approval from the Japanese Pharmaceutical Affairs Law and is commercially available in Japan. We assessed image quality of dbPET at the detector's edge, where the mammary glands near the chest wall are located in phantom and clinical studies.Methods: A breast phantom with four spheres (16, 10, 7.5, and 5 mm diameter) was filled with 18F-fluorodeoxyglucose solution (sphere-to-background ratio, 8:1). The spheres occupied five different positions from the top edge to the centre of the detector and were scanned for 5 min in each position. Reconstructed images were visually evaluated, and the contrast-to-noise ratio (CNR), contrast recovery coefficient (CRC) for the 5-mm sphere, and coefficient of variation of the background (CVB) were calculated. Subsequently, clinical images obtained with standard spine PET/CT and prone dbPET were retrospectively analysed. Tumour-to-background ratios (TBRs) between breast cancer near the chest wall (close to the detector’s edge; peripheral group) and at other locations (non-peripheral group) were compared. The TBR of each lesion was compared between dbPET and PET/computed tomography (CT).Results: Closer to the detector’s edge, the CNR and CRC decreased while the CVB increased in the phantom study. The disadvantages of this placement were visually confirmed. Regarding clinical images, TBR of dbPET was significantly higher than that of PET/CT in both the peripheral (12.38±6.41 vs 6.73±3.5, p=0.0006) and non-peripheral (12.44±5.94 vs 7.71±7.1, p=0.0183) groups. There was no significant difference in TBR of dbPET between the peripheral and non-peripheral groups (12.4±6.4 vs 12.4±5.9, p=0.8261).Conclusion: The phantom study revealed poorer image quality closer to the detector edge at a depth of <2 cm from the detector's edge than at other more central parts. In clinical studies, however, the visibility of breast lesions with dbPET was the same regardless of the lesion position, and it was higher than that in PET/CT. dbPET has a great potential for detecting breast lesions near the chest wall if they are at least 2 cm from the edge of the FOV, even in young women with small breasts.

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