Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine

2013 ◽  
Vol 40 (12) ◽  
pp. 121708 ◽  
Author(s):  
Dennis Mackin ◽  
Yupeng Li ◽  
Michael B. Taylor ◽  
Matthew Kerr ◽  
Charles Holmes ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Patient Specific ◽  
Spot Scanning

scholarly journals Towards Effective and Efficient Patient-Specific Quality Assurance for Spot Scanning Proton Therapy

Cancers ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 631-647 ◽  
Author(s):  
X. Zhu ◽  
Yupeng Li ◽  
Dennis Mackin ◽  
Heng Li ◽  
Falk Poenisch ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Patient Specific ◽  
Spot Scanning

scholarly journals Use of treatment log files in spot scanning proton therapy as part of patient-specific quality assurance

2013 ◽  
Vol 40 (2) ◽  
pp. 021703 ◽  
Author(s):  
Heng Li ◽  
Narayan Sahoo ◽  
Falk Poenisch ◽  
Kazumichi Suzuki ◽  
Yupeng Li ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Patient Specific ◽  
Log Files ◽  
Spot Scanning

Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Results from 309 Treatment Plans

2014 ◽  
pp. 141211132049007
Author(s):  
Dennis Mackin ◽  
X. Ronald Zhu ◽  
Falk Poenisch ◽  
Heng Li ◽  
Narayan Sahoo ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Patient Specific ◽  
Spot Scanning ◽  
Treatment Plans

scholarly journals Feasibility of patient specific quality assurance for proton therapy based on independent dose calculation and predicted outcomes

2020 ◽  
Vol 150 ◽  
pp. 136-141
Author(s):  
Arturs Meijers ◽  
Gabriel Guterres Marmitt ◽  
Kelvin Ng Wei Siang ◽  
Arjen van der Schaaf ◽  
Antje C. Knopf ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Patient Specific

scholarly journals Transitioning from measurement-based to combined patient-specific quality assurance for intensity-modulated proton therapy

2020 ◽  
Vol 93 (1107) ◽  
pp. 20190669 ◽  
Author(s):  
Mei Chen ◽  
Pablo Yepes ◽  
Yoshifumi Hojo ◽  
Falk Poenisch ◽  
Yupeng Li ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Dose Calculation ◽  
Patient Specific ◽  
Calculation Algorithm ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Passing Rate ◽  
Clinical Scenarios ◽  
Beam Modeling

Objective: This study is part of ongoing efforts aiming to transit from measurement-based to combined patient-specific quality assurance (PSQA) in intensity-modulated proton therapy (IMPT). A Monte Carlo (MC) dose-calculation algorithm is used to improve the independent dose calculation and to reveal the beam modeling deficiency of the analytical pencil beam (PB) algorithm. Methods: A set of representative clinical IMPT plans with suboptimal PSQA results were reviewed. Verification plans were recalculated using an MC algorithm developed in-house. Agreements of PB and MC calculations with measurements that quantified by the γ passing rate were compared. Results: The percentage of dose planes that met the clinical criteria for PSQA (>90% γ passing rate using 3%/3 mm criteria) increased from 71.40% in the original PB calculation to 95.14% in the MC recalculation. For fields without beam modifiers, nearly 100% of the dose planes exceeded the 95% γ passing rate threshold using the MC algorithm. The model deficiencies of the PB algorithm were found in the proximal and distal regions of the SOBP, where MC recalculation improved the γ passing rate by 11.27% (p < 0.001) and 16.80% (p < 0.001), respectively. Conclusions: The MC algorithm substantially improved the γ passing rate for IMPT PSQA. Improved modeling of beam modifiers would enable the use of the MC algorithm for independent dose calculation, completely replacing additional depth measurements in IMPT PSQA program. For current users of the PB algorithm, further improving the long-tail modeling or using MC simulation to generate the dose correction factor is necessary. Advances in knowledge: We justified a change in clinical practice to achieve efficient combined PSQA in IMPT by using the MC algorithm that was experimentally validated in almost all the clinical scenarios in our center. Deficiencies in beam modeling of the current PB algorithm were identified and solutions to improve its dose-calculation accuracy were provided.

scholarly journals Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Results from 309 Treatment Plans

2014 ◽  
Vol 1 (3) ◽  
pp. 711-720 ◽  
Author(s):  
Dennis Mackin ◽  
X. Ronald Zhu ◽  
Falk Poenisch ◽  
Heng Li ◽  
Narayan Sahoo ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Patient Specific ◽  
Spot Scanning ◽  
Treatment Plans

MO-F-16A-05: Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Our Methodology and Results From 295 Treatment Plans

2014 ◽  
Vol 41 (6Part25) ◽  
pp. 429-429
Author(s):  
D Mackin ◽  
X Zhang ◽  
Y Li ◽  
H Li ◽  
R Wu ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Patient Specific ◽  
Spot Scanning ◽  
Treatment Plans

scholarly journals Quality assurance evaluation of spot scanning beam proton therapy with an anthropomorphic prostate phantom

2013 ◽  
Vol 86 (1031) ◽  
pp. 20130390 ◽  
Author(s):  
K Iqbal ◽  
M Gillin ◽  
P A Summers ◽  
S Dhanesar ◽  
K A Gifford ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Scanning Beam ◽  
Spot Scanning ◽  
Beam Proton
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