WE-C-WAB-05: A Novel Integrated X-Ray and Fluorescence Tomography System for Small Animal Radiation Research Platform

2013 ◽  
Vol 40 (6Part29) ◽  
pp. 478-478
Author(s):  
K Wang ◽  
Y Yang ◽  
S Eslami ◽  
I Iordachita ◽  
M Patterson ◽  
...  
2015 ◽  
Vol 42 (6Part39) ◽  
pp. 3674-3674
Author(s):  
K Wang ◽  
Z Bin ◽  
X He ◽  
I Iordachita ◽  
J Wong

2014 ◽  
Vol 110 ◽  
pp. S105
Author(s):  
K.K.-H. Wang ◽  
Y. Yang ◽  
S. Eslami ◽  
I. Iordachita ◽  
M.S. Patterson ◽  
...  

2008 ◽  
Vol 71 (5) ◽  
pp. 1591-1599 ◽  
Author(s):  
John Wong ◽  
Elwood Armour ◽  
Peter Kazanzides ◽  
Iulian Iordachita ◽  
Erik Tryggestad ◽  
...  

2014 ◽  
Vol 41 (6Part32) ◽  
pp. 556-556
Author(s):  
K Wang ◽  
B Zhang ◽  
S Eslami ◽  
I Iordachita ◽  
M Patterson ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Yuyang Li ◽  
Kian Shaker ◽  
Jakob C. Larsson ◽  
Carmen Vogt ◽  
Hans M. Hertz ◽  
...  

Nanoparticles (NPs) have been used as contrast agents for several bioimaging modalities. X-ray fluorescence (XRF) tomography can provide sensitive and quantitative 3D detection of NPs. With spectrally matched NPs as contrast agents, we demonstrated earlier in a laboratory system that XRF tomography could achieve high-spatial-resolution tumor imaging in mice. Here, we present the synthesis, characterization, and evaluation of a library of NPs containing Y, Zr, Nb, Rh, and Ru that have spectrally matched K-shell absorption for the laboratory scale X-ray source. The K-shell emissions of these NPs are spectrally well separated from the X-ray probe and the Compton background, making them suitable for the lab-scale XRF tomography system. Their potential as XRF contrast agents is demonstrated successfully in a small-animal equivalent phantom, confirming the simulation results. The diversity in the NP composition provides a flexible platform for a better design and biological optimization of XRF tomography nanoprobes.


2018 ◽  
Vol 45 (5) ◽  
pp. 2252-2265 ◽  
Author(s):  
Nathan Cho ◽  
Panagiotis Tsiamas ◽  
Esteban Velarde ◽  
Erik Tryggestad ◽  
Robert Jacques ◽  
...  

2012 ◽  
Vol 39 (6Part23) ◽  
pp. 3899-3899
Author(s):  
W Ngwa ◽  
P Tsiamas ◽  
P Zygmanski ◽  
M Makrigiorgos ◽  
R Berbeco

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