SU-E-T-561: Small Target Dose Calculation Accuracy for Multiple-Target Single-Isocenter VMAT

2013 ◽  
Vol 40 (6Part19) ◽  
pp. 334-334
Author(s):  
R Popple ◽  
X Wu ◽  
Y Yuan ◽  
R Cardan ◽  
J Duan ◽  
...  
2018 ◽  
Vol 52 ◽  
pp. 73-74
Author(s):  
Georgia Prentou ◽  
Pantelis Karaiskos ◽  
Panagiotis Papagiannis ◽  
Evaggelos Pantelis ◽  
Efi Koutsouveli

2018 ◽  
Vol 19 (5) ◽  
pp. 651-658 ◽  
Author(s):  
Saeed Ahmed ◽  
Jeff Kapatoes ◽  
Geoffrey Zhang ◽  
Eduardo G. Moros ◽  
Vladimir Feygelman

Author(s):  
Leonie Brodbek ◽  
Jana Kretschmer ◽  
Katrin Büsing ◽  
Hui Khee Looe ◽  
Bjoern Poppe ◽  
...  

Abstract The RUBY head phantom in combination with the System QA insert MultiMet can be used for simultaneous point dose measurements at an isocentric and two off-axis positions. This study investigates the suitability of the system for systematic integral end-to-end testing of single-isocenter multiple target stereotactic treatments. Several volumetric modulated arc therapy plans were optimized on a planning CT of the phantom positioned in a stereotactic mask on the stereotactic treatment board. The plans were created for three artificial spherical target volumes centred around the measurement positions in the MultiMet insert. Target diameters between 5 and 40 mm were investigated. Coplanar and non-coplanar plans were optimized using the collapsed cone algorithm of the Oncentra Masterplan treatment planning system and recalculated with the Monte Carlo algorithm of the Monaco treatment planning system. Measurements were performed at an Elekta Synergy linear accelerator. The head phantom was positioned according to clinical workflow comprising immobilization and CBCT imaging. Simultaneous point dose measurements at all target positions were performed with three PinPoint 3D chambers (type 31022) as well as three microDiamond (type 60019) detectors and compared to the treatment planning system calculations. Furthermore, the angular dependence of the detector response was investigated to estimate the associated impact on the measured point dose values. Considering all investigated plans, PTV diameters and positions, the point doses calculated with the Monaco treatment planning system and the microDiamond measurements differed within 3.5%, whereas the PinPoint 3D showed differences of up to 6.9%. Point dose differences determined in comparison to the Oncentra Masterplan dose calculations were larger. The RUBY system was shown to be suitable for end-to-end testing of complex treatment scenarios such as single-isocenter multiple target plans.


2018 ◽  
Vol 19 (2) ◽  
pp. 154-159 ◽  
Author(s):  
Dandan Zheng ◽  
Vivek Verma ◽  
Shuo Wang ◽  
Xiaoying Liang ◽  
Sumin Zhou

2006 ◽  
Vol 45 (05) ◽  
pp. 206-212 ◽  
Author(s):  
C. Rubner ◽  
A. Bauhofer ◽  
F. Berce ◽  
W. J. G. Oyen ◽  
J. Goecke ◽  
...  

Summary:Purpose: Dose calculation for radioiodine therapy (RIT) of multifocal autonomies (MFA) is a problem as therapeutic outcome may be worse than in other kinds of autonomies. We compared different dosimetric concepts in our patients. Patients, methods: Data from 187 patients who had undergone RIT for MFA (Marinelli algorithm, volumetric compromise) were included in the study. For calculation, either a standard or a measured half-life had been used and the dosimetric compromise (150 Gy, total thyroid volume). Therapeutic activities were calculated by 2 alternative concepts and compared to therapeutic success achieved (concept of TcTUs-based calculation of autonomous volume with 300 Gy and TcTUs-based adaptation of target dose on total thyroid volume). Results: If a standard half-life is used, therapeutic success was achieved in 90.2%(hypothyroidism 23,1%, n=143). If a measured half-life was used the success rate was 93.1% (13,6% hypothyroidism, n=44). These differences were statistically not significant, neither for all patients together nor for subgroups eu-, hypo-, or hyperthyroid after therapy (ANOVA, all p>0.05). The alternative dosimetric concepts would have resulted either in significantly lower organ doses (TcTUs-based calculation of autonomous volume; 80.76±80.6 Gy versus 125.6±46.3 Gy; p<0.0001) or in systematic over-treatment with significantly higher doses (TcTUs-adapted concept; 164.2±101.7 Gy versus 125.6±46.3 Gy; p=0.0097). Conclusions: TcTUsbased determination of the autonomous volume should not be performed, the TcTUs-based adaptation of the target dose will only increase the rate of hypothyroidism. A standard half-life may be used in pre-therapeutic dosimetry for RIT of MFA. If so, individual therapeutic activities may be calculated based on thyroid size corrected to the 24h ITUs without using Marinelli’s algorithm.


Author(s):  
Justin Roper ◽  
Vorakarn Chanyavanich ◽  
Gregory Betzel ◽  
Jeffrey Switchenko ◽  
Anees Dhabaan

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