SU-E-T-512: Monte Carlo Dose Verification of Pencil Beam Scanning Proton Therapy

2013 ◽  
Vol 40 (6Part18) ◽  
pp. 323-323
Author(s):  
D Giantsoudi ◽  
B Clasie ◽  
C Grassberger ◽  
S Dowdell ◽  
N Depauw ◽  
...  
2021 ◽  
Vol 20 ◽  
pp. 153303382110330
Author(s):  
Chunbo Liu ◽  
Meng Wei Ho ◽  
Jiyeon Park ◽  
Wen Chien Hsi ◽  
Xiaoying Liang ◽  
...  

Purpose: To commission MCsquare (a multi-cores CPU-based dose calculation engine) for pencil beam scanning (PBS) proton therapy, integrate it into RayStation treatment plan system (TPS) to create a dedicated platform for fast independent dose verification. Method: A MCsquare-based independent dose verification platform (MC2InRS) was developed to realize automatic dose re-calculation for clinical use, including data preparation, dose calculation, 2D/3D gamma analysis. MCsquare was commissioned based on in-air lateral dose profiles, integrated depth dose, and the absolute dose of different beam energies for Proteus®ONE. MC2InRS was validated with measurement data using various targets and depths in a water phantom. This study also investigated 15 clinical cases to demonstrate the feasibility and effectiveness of MC2InRS platform in clinic practice. Results: Between simulation and measurement, the distal range differences at 80% (R80) and 20% (R20) dose levels for each energy were below 0.05 mm, and 0.1 mm, respectively, and the absolute dose differences were below 0.5%. 29 out of 36 QA planes reached a 100% gamma passing rate (GPR) for 2%/2mm criteria, and a minimum of 98.3% gamma was obtained in water phantom between simulation and measurement. For the 15 clinical cases investigated, the average 2D GPR (2%/2mm) was 95.4%, 99.3% for MCsquare vs. measurement, MCsquare vs. TPS, respectively. The average 3D GPR (2%/2mm) was 98.9%, 95.3% for MCsquare vs. TPS in water, and computed tomography (CT), respectively. Conclusion: MC2InRS, a fast, independent dose verification platform, has been developed to perform dose verification with high accuracy and efficiency for Pencil Bream Scanning (PBS). Its potential to be applied in routine clinical practice has also been discussed.


2020 ◽  
Vol 47 (10) ◽  
pp. 5343-5356
Author(s):  
Blake R. Smith ◽  
Mark Pankuch ◽  
Daniel E. Hyer ◽  
Wesley S. Culberson

2012 ◽  
Vol 57 (10) ◽  
pp. 2829-2842 ◽  
Author(s):  
Stephen J Dowdell ◽  
Benjamin Clasie ◽  
Nicolas Depauw ◽  
Peter Metcalfe ◽  
Anatoly B Rosenfeld ◽  
...  

2021 ◽  
Author(s):  
Nicholas P. Nelson ◽  
Wesley S. Culberson ◽  
Daniel E. Hyer ◽  
Theodore J. Geoghegan ◽  
Kaustubh A. Patwardhan ◽  
...  

Author(s):  
Bing-Hao Chiang ◽  
Austin Bunker ◽  
Hosang Jin ◽  
Salahuddin Ahmad ◽  
Yong Chen

Abstract Aim: As the number of proton therapy facilities has steadily increased, the need for the tool to provide precise dose simulation for complicated clinical and research scenarios also increase. In this study, the treatment head of Mevion HYPERSCAN pencil beam scanning (PBS) proton therapy system including energy modulation system (EMS) and Adaptive Aperture™ (AA) was modelled using TOPAS (TOolkit for PArticle Simulation) Monte Carlo (MC) code and was validated during commissioning process. Materials and methods: The proton beam characteristics including integral depth doses (IDDs) of pristine Bragg peak and in-air beam spot sizes were simulated and compared with measured beam data. The lateral profiles, with and without AA, were also verified against calculation from treatment planning system (TPS). Results: All beam characteristics for IDDs and in-air spot size agreed well within 1 mm and 10% separately. The full width at half maximum and penumbra of lateral dose profile also agree well within 2 mm. Finding: The TOPAS MC simulation of the MEVION HYPERSCAN PBS proton therapy system has been modelled and validated; it could be a viable tool for research and verification of the proton treatment in the future.


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