SU-E-J-161: In Vivo Dose Measurement During IGRT with KV Cone Beam CT

2013 ◽  
Vol 40 (6Part9) ◽  
pp. 188-188
Author(s):  
P Ravindran ◽  
S Kumar ◽  
S Sharma ◽  
S John
2018 ◽  
Vol 24 (6) ◽  
pp. 693-701 ◽  
Author(s):  
Dominik F Vollherbst ◽  
Ruth Otto ◽  
Thuy Do ◽  
Hans U Kauczor ◽  
Martin Bendszus ◽  
...  

Background and purpose A frequently reported drawback of ethylene vinyl alcohol copolymer-based liquid embolic agents is the production of artifacts in diagnostic imaging. New embolic agents, such as Precipitating hydrophobic injectable liquid (PHIL; MicroVention, Tustin, CA, USA), are supposed to induce significantly fewer artifacts. The purpose of this study is to assess the degree of artifacts induced by the liquid embolic agents Onyx (Medtronic Neurovascular, Irvine, CA, USA) and PHIL in conventional computed tomography (CT), cone-beam CT and magnetic resonance imaging (MRI) in an experimental in vivo model. Materials and methods In 10 pigs the rete mirabile was embolized with Onyx ( n = 5) or PHIL ( n = 5). After embolization, conventional CT, cone-beam CT and MRI were performed. The degree of artifacts was graded qualitatively (five-point scale; for CT and MRI) and quantitatively (HUs of well-defined regions of interest (ROIs); for CT only). Results Artifacts were significantly more severe for Onyx both in the qualitative (e.g. conventional CT: 2 versus 5 (medians); p = 0.008) and in the quantitative image analysis (e.g. cone-beam CT: standard deviation of a ROI near to the embolic agent cast, 94 HU versus 38 HU (medians); p = 0.008). Neither Onyx nor PHIL produced any apparent artifacts in MRI. Conclusion PHIL produces fewer artifacts than Onyx in conventional CT and cone-beam CT in an experimental in vivo model.


2019 ◽  
Vol 41 (4) ◽  
pp. 461-468 ◽  
Author(s):  
Andrea Borghesi ◽  
Silvia Michelini ◽  
Angelo Zigliani ◽  
Ingrid Tonni ◽  
Roberto Maroldi
Keyword(s):  

2009 ◽  
Vol 92 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Shiu-Chen Jeng ◽  
Chiao-Ling Tsai ◽  
Wen-Tung Chan ◽  
Chuan-Jong Tung ◽  
Jian-Kuen Wu ◽  
...  

2013 ◽  
Vol 40 (6Part5) ◽  
pp. 127-127
Author(s):  
P Deman ◽  
P Atwal ◽  
C Duzenli ◽  
Y Thakur ◽  
N Ford

2016 ◽  
Vol 45 (3) ◽  
pp. 811-818 ◽  
Author(s):  
Katariina A. H. Myller ◽  
Mikael J. Turunen ◽  
Juuso T. J. Honkanen ◽  
Sami P. Väänänen ◽  
Jarkko T. Iivarinen ◽  
...  

2021 ◽  
Author(s):  
Michael H. Wang ◽  
Anthony Kim ◽  
Mark Ruschin ◽  
Hendrick Tan ◽  
Hany Soliman ◽  
...  

Abstract Background Magnetic Resonance Imaging (MRI)-Linear Accelerator (MR-Linac) radiotherapy requires special consideration for secondary electron interactions within the magnetic field, which can alter dose deposition at air-tissue interfaces. Methods Thirty-seven consecutive glioma patients treated during their radiotherapy course with at least one fraction delivered on MR-Linac or Cone Beam CT (CBCT)-guided Linac, were analyzed. Treatment planning for both systems were completed prior to radiotherapy initiation and approved for clinical delivery using commercial treatment planning systems (TPS): a Monte Carlo calculation-based or convolution calculation-based TPS for MR-Linac or CBCT-Linac, respectively. Dosimetric parameters for planning target volume (PTV), organs-at-risk (OARs), and air-tissue interface were compared. In vivo skin dose during a single fraction of MR-Linac and CBCT-Linac treatment was measured using an Optically Stimulated Luminescent Dosimeter (OSLD) and correlated with TPS skin dose. Results Monte Carlo-based MR-Linac plans and convolution-based CBCT-Linac plans exhibited minimal differences in PTV and OAR parameters. However, MR-Linac plans had greater doses within tissues surrounding air cavities (1.52 Gy higher mean Dmean, p < 0.0001) and skin (1.10 Gy higher mean Dmean, p < 0.0001). In vivo OSLD skin readings were 14.5% greater for MR-Linac treatments (p = 0.0027), and were more accurately predicted by Monte Carlo-based calculation (ρ = 0.95, p < 0.0001) vs. convolution-based (ρ = 0.80, p = 0.0096). Conclusions The magnetic field’s dosimetric impact was minimal for PTV and OARs in glioma as compared to standard CBCT-Linac treatment plans. However, skin doses were significantly greater with the MR-Linac and correlated with in vivo measurements. Future MR-Linac planning processes are being designed to account for skin dosimetry and treatment delivery.


2021 ◽  
pp. neurintsurg-2021-018018
Author(s):  
Niclas Schmitt ◽  
Charlotte S Weyland ◽  
Lena Wucherpfennig ◽  
Christof M Sommer ◽  
Martin Bendszus ◽  
...  

BackgroundOnyx is frequently used for endovascular embolization of intracranial arteriovenous malformations (AVMs) and dural arteriovenous fistulas (dAVFs). One drawback of using Onyx is the generation of artifacts in cone-beam CT (CBCT). These artifacts can represent an obstacle for the detection of periprocedural hemorrhage or planning of subsequent radiosurgery. This study investigates the effect of artifact reduction by the syngo DynaCT SMART Metal Artifact Reduction (MAR) software.MethodsA standardized in vitro tube model (n=10) was filled with Onyx 18 and CBCT image acquisition was conducted in a brain imaging phantom. Furthermore, post-interventional CBCT images of 20 patients with AVM (n=13) or dAVF (n=7), each treated with Onyx, were investigated. The MAR software was applied for artifact reduction. Artifacts of the original and the post-processed images were analyzed quantitatively (standard deviation in a region of interest on the layer providing the most artifacts) and qualitatively. For the patient images, the effect of the MAR software on brain parenchyma on artifact-free images was further investigated.ResultsQuantitative and qualitative analyses of both datasets demonstrated a lower degree of artifacts in the post-processed images (eg, patient images: 38.30±22.03 density units (no MAR; mean SD±SD) vs 19.83±12.31 density units (with MAR; p<0.001). The MAR software had no influence on the brain parenchyma in artifact-free images.ConclusionThe MAR software significantly reduced the artifacts evoked by Onyx in CBCT without affecting the visualization of brain parenchyma on artifact-free images. Applying this software could thus improve the quality of periprocedural CBCT images after embolization with Onyx.


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