SU-E-J-40: Automated Estimation of Lung Tumor Locations for Tumor-Based Patient Setup Using MV-CBCT Images in Stereotactic Body Radiotherapy

2013 ◽  
Vol 40 (6Part7) ◽  
pp. 158-158
Author(s):  
S Yoshidome ◽  
H Arimura ◽  
K Nakamura ◽  
Y Shioyama ◽  
K Atsumi ◽  
...  
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Patient Setup

Clinical outcome of stereotactic body radiotherapy of 54 Gy in nine fractions for patients with localized lung tumor using a custom-made immobilization system

2007 ◽  
Vol 25 (6) ◽  
pp. 289-294 ◽  
Author(s):  
Masahiko Aoki ◽  
Yoshinao Abe ◽  
Hidehiro Kondo ◽  
Yoshiomi Hatayama ◽  
Hideo Kawaguchi ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Custom Made

Interfractional Variations of Lung Tumor in the Stereotactic Body Radiotherapy with Cine EPID at Treatment

2010 ◽  
Vol 78 (3) ◽  
pp. S682
Author(s):  
Y. Ueda ◽  
K. Tsujii ◽  
K. Shirai ◽  
M. Miyazaki ◽  
K. Miyagi ◽  
...  
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Lung Tumor

SU-GG-J-58: Stereotactic Body Radiotherapy: Computer-Assisted Verification of a Lung Tumor Region Using EPID without Implanted Markers

2010 ◽  
Vol 37 (6Part10) ◽  
pp. 3158-3158
Author(s):  
H Arimura ◽  
Y Shioyama ◽  
K Nakamura ◽  
T Yoshitake ◽  
S Anai ◽  
...  
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Computer Assisted ◽  
Tumor Region

scholarly journals Prognostic impact of average iodine density assessed by dual-energy spectral imaging for predicting lung tumor recurrence after stereotactic body radiotherapy

2016 ◽  
Vol 57 (4) ◽  
pp. 381-386 ◽  
Author(s):  
Masahiko Aoki ◽  
Katsumi Hirose ◽  
Mariko Sato ◽  
Hiroyoshi Akimoto ◽  
Hideo Kawaguchi ◽  
...  
Keyword(s):  
Local Control ◽  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Lung Metastases ◽  
Prognostic Significance ◽  
Lung Tumors ◽  
Dual Energy ◽  
Hypoxic Cell ◽  
Prognostic Impact ◽  
Lung Cancers

Abstract The purpose of this study was to investigate the prognostic significance of average iodine density as assessed by dual-energy computed tomography (DE-CT) for lung tumors treated with stereotactic body radiotherapy (SBRT). From March 2011 to August 2014, 93 medically inoperable patients with 74 primary lung cancers and 19 lung metastases underwent DE-CT prior to SBRT of a total dose of 45–60 Gy in 5–10 fractions. Of these 93 patients, nine patients had two lung tumors. Thus, 102 lung tumors were included in this study. DE-CT was performed for pretreatment evaluation. Regions of interest were set for the entire tumor, and average iodine density was obtained using a dedicated imaging software and evaluated with regard to local control. The median follow-up period was 23.4 months (range, 1.5–54.5 months). The median value of the average iodine density was 1.86 mg/cm 3 (range, 0.40–9.27 mg/cm 3 ). Two-year local control rates for the high and low average iodine density groups divided by the median value of the average iodine density were 96.9% and 75.7% ( P = 0.006), respectively. Tumors with lower average iodine density showed a worse prognosis, possibly reflecting a hypoxic cell population in the tumor. The average iodine density exhibited a significant impact on local control. Our preliminary results indicate that iodine density evaluated using dual-energy spectral CT may be a useful, noninvasive and quantitative assessment of radio-resistance caused by presumably hypoxic cell populations in tumors.

scholarly journals Stereotactic body radiotherapy for adenoid cystic carcinoma metastatic to the lung: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Daijiro Kobayashi ◽  
Takanori Abe ◽  
Jun-ichi Saitoh ◽  
Takahiro Oike ◽  
Hiro Sato ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Lung Metastases ◽  
Neck Region ◽  
Late Toxicity ◽  
Normal Lung ◽  
High Dose ◽  
Total Lung Volume ◽  
Adenoid Cystic

Abstract Background Adenoid cystic carcinoma (ACC) is a rare malignant tumor involving mostly the head and neck region, and frequently the salivary glands. The development of lung metastasis after treatment of the primary tumor is a common occurrence in ACC. Although lung metastases show a slow rate of growth, approximately 10% of patients die from distant metastases. The radioresistance of ACC limits the efficacy of conventional radiotherapy for lung metastases, and the optimal dose remains to be determined. Stereotactic body radiotherapy (SBRT) using CyberKnife can deliver a high dose to the lung tumor, while sparing the surrounding normal lung tissues, leading to favorable local control in non-squamous cell lung cancer and metastatic lung tumors. We report a case of lung metastases from ACC treated successfully with SBRT using CyberKnife. Case presentation A 76-year-old Japanese man with ACC who was treated with carbon ion radiotherapy for a primary oropharynx tumor presented with three metastatic lesions in the lung. The tumor masses were located in the right upper, right lower, and left lower lobes of the lungs. Surgical resection was not indicated because of the presence of multiple tumors. The patient underwent SBRT at 60 Gy in 10 sequential fractions for each tumor. The biologically effective dose based on an alpha/beta ratio of 2 Gy was 240 Gy per tumor. The percentage of the total lung volume irradiated with >20 Gy was 4.9%, 3.2%, and 2.6% for each tumor. The patient developed acute radiation pneumonitis during the initial therapy, which resolved at 6 months after the CyberKnife treatment. At 21 months after the first CyberKnife treatment, three tumors showed no signs of recurrence. No late toxicity was observed. Conclusions SBRT using CyberKnife is an effective and feasible approach to the management of multiple lung metastases of ACC.

scholarly journals P2.05-002 A Pilot Study on the Safety and the Efficacy of Dose Escalation in Stereotactic Body Radiotherapy for Peripheral Lung Tumor

2017 ◽  
Vol 12 (11) ◽  
pp. S2403-S2404
Author(s):  
T. Mitsuyoshi ◽  
Y. Matsuo ◽  
T. Shintani ◽  
Y. Iizuka ◽  
N. Ueki ◽  
...  
Keyword(s):  
Pilot Study ◽  
Dose Escalation ◽  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Peripheral Lung

scholarly journals Feasibility Study of Automated Framework for Estimating Lung Tumor Locations for Target-Based Patient Positioning in Stereotactic Body Radiotherapy

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Satoshi Yoshidome ◽  
Hidetaka Arimura ◽  
Katsumasa Nakamura ◽  
Yoshiyuki Shioyama ◽  
Kazushige Atsumi ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Stereotactic Body Radiotherapy ◽  
Template Matching ◽  
Lung Tumor ◽  
Patient Positioning ◽  
Cone Beam ◽  
Matching Technique ◽  
Euclidean Distances ◽  
Lung Screening ◽  
Structure Enhancement

Objective.To investigate the feasibility of an automated framework for estimating the lung tumor locations for tumor-based patient positioning with megavolt-cone-beam computed tomography (MV-CBCT) during stereotactic body radiotherapy (SBRT).Methods.A lung screening phantom and ten lung cancer cases with solid lung tumors, who were treated with SBRT, were employed to this study. The locations of tumors in MV-CBCT images were estimated using a tumor-template matching technique between a tumor template and the MV-CBCT. Tumor templates were produced by cropping the gross tumor volume (GTV) regions, which were enhanced by a Sobel filter or a blob structure enhancement (BSE) filter. Reference tumor locations (grand truth) were determined based on a consensus between a radiation oncologist and a medical physicist.Results.According to the results of the phantom study, the average Euclidean distances of the location errors in the original, Sobel-filtered, and BSE-filtered images were 2.0 ± 4.1 mm, 12.8 ± 9.4 mm, and 0.4 ± 0.5 mm, respectively. For clinical cases, these were 3.4 ± 7.1 mm, 7.2 ± 11.6 mm, and 1.6 ± 1.2 mm, respectively.Conclusion.The feasibility study suggests that our proposed framework based on the BSE filter may be a useful tool for tumor-based patient positioning in SBRT.

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