Characterization of a cable-free system based on p-type MOSFET detectors for “in vivo ” entrance skin dose measurements in interventional radiology

2012 ◽  
Vol 39 (8) ◽  
pp. 4866-4874 ◽  
Author(s):  
Maria Daniela Falco ◽  
Marco D'Andrea ◽  
Lidia Strigari ◽  
Daniela D'Alessio ◽  
Francesco Quagliani ◽  
...  
Keyword(s):  
Interventional Radiology ◽  
Skin Dose ◽  
Free System ◽  
Entrance Skin Dose ◽  
P Type ◽  
Dose Measurements

Chest X-rays of newborns in a medical facility: variation between the entrance skin dose measurements using the indirect and direct methods for clinical dose audit

2021 ◽  
Author(s):  
Akintayo Daniel Omojola ◽  
Michael Onoriode Akpochafor ◽  
Samuel Olaolu Adeneye ◽  
Isiaka Olusola Akala ◽  
Azuka Anthonio Agboje
Keyword(s):  
Direct Methods ◽  
Skin Dose ◽  
Medical Facility ◽  
X Rays ◽  
Clinical Dose ◽  
Entrance Skin Dose ◽  
Dose Measurements

Systematic in vivo dosimetry for quality assurance using diodes 2: Assessing radiotherapy techniques and developing an appropriate action protocol

2004 ◽  
Vol 4 (4) ◽  
pp. 143-154 ◽  
Author(s):  
R. Appleyard ◽  
K. Ball ◽  
F. E. Hughes ◽  
W. Kilby ◽  
R. Nicholls ◽  
...  
Keyword(s):  
Head And Neck ◽  
In Vivo Dosimetry ◽  
Entrance Dose ◽  
Treatment Category ◽  
P Type ◽  
Dose Measurements ◽  
Action Levels

Purpose: Having previously reviewed the implementation of systematic in vivo dosimetry at the Norfolk and Norwich Hospital this paper examines the results of entrance dose measurements for specific sites/techniques and determines whether different action/alert protocols are required for these different categories.Methods and materials: Entrance dose measurements using p-type diodes were analysed for the following treatment categories: Breast, head and neck in beam direction shell, abdomino-pelvic and intrathoracic. A 4% tolerance was applied.Results: Mean deviations from expected dose and proportion of measurements exceeding tolerance were: Breast: +1.15%±3.04% (1SD), 238/1073≥4%; Head and neck: +0.35%±2.20% (1SD), 21/326≥4%; Abdomino-pelvic: +0.52%±2.75% (1SD), 93/712≥4%; Intrathoracic: −0.01%±2.75% (1SD), 22/119≥4%. Significant improvements in results for breast patients were noted following the introduction of a commercial breast board. The results for abdomino-pelvic patients confirmed a substantial variation in diode response under short FSD, wedged fields at 16MV (that had not been corrected for). The statistical uncertainty in dose measurement for each treatment category was calculated in order to assist determination of appropriate tolerance levels.Conclusions: A blanket tolerance of 4% was generally too low given the extent of measurement uncertainty. The relatively high number of readings outside tolerance where identification of errors was difficult/impossible resulted in inconsistent application of the action protocol. Some widening of tolerances is likely to improve quality of procedure and treatment. Appropriate action levels are recommended for each treatment category.

scholarly journals Functional Requirement of Noncoding Y RNAs for Human Chromosomal DNA Replication

2006 ◽  
Vol 26 (18) ◽  
pp. 6993-7004 ◽  
Author(s):  
Christo P. Christov ◽  
Timothy J. Gardiner ◽  
Dávid Szüts ◽  
Torsten Krude
Keyword(s):  
Dna Replication ◽  
Functional Characterization ◽  
Noncoding Rnas ◽  
Biological Processes ◽  
Replication Forks ◽  
Chromosomal Dna ◽  
Free System ◽  
Specific Degradation

ABSTRACT Noncoding RNAs are recognized increasingly as important regulators of fundamental biological processes, such as gene expression and development, in eukaryotes. We report here the identification and functional characterization of the small noncoding human Y RNAs (hY RNAs) as novel factors for chromosomal DNA replication in a human cell-free system. In addition to protein fractions, hY RNAs are essential for the establishment of active chromosomal DNA replication forks in template nuclei isolated from late-G1-phase human cells. Specific degradation of hY RNAs leads to the inhibition of semiconservative DNA replication in late-G1-phase template nuclei. This inhibition is negated by resupplementation of hY RNAs. All four hY RNAs (hY1, hY3, hY4, and hY5) can functionally substitute for each other in this system. Mutagenesis of hY1 RNA showed that the binding site for Ro60 protein, which is required for Ro RNP assembly, is not essential for DNA replication. Degradation of hY1 RNA in asynchronously proliferating HeLa cells by RNA interference reduced the percentages of cells incorporating bromodeoxyuridine in vivo. These experiments implicate a functional role for hY RNAs in human chromosomal DNA replication.

SU-E-T-241: Characterization of MOSFET Detectors for in Vivo Dosimetry in Interventional Radiology and for Dose Reconstruction in Case of Accident

2011 ◽  
Vol 38 (6Part14) ◽  
pp. 3542-3542
Author(s):  
C Bassinet ◽  
C Huet ◽  
M Baumann ◽  
C Etard ◽  
J-L Réhel ◽  
...  
Keyword(s):  
Interventional Radiology ◽  
In Vivo Dosimetry ◽  
Dose Reconstruction

scholarly journals Optimization of skin dose using in-vivo MOSFET dose measurements in bolus/non-bolus fraction ratio: A VMAT and a 3DCRT study

2019 ◽  
Vol 20 (2) ◽  
pp. 63-70 ◽  
Author(s):  
Anabela G. Dias ◽  
Diana F. S. Pinto ◽  
Maria F. Borges ◽  
Maria H. Pereira ◽  
João A. M. Santos ◽  
...  
Keyword(s):  
Skin Dose ◽  
Dose Measurements

Disassembly of the Drosophila nuclear lamina in a homologous cell-free system

1995 ◽  
Vol 108 (5) ◽  
pp. 2027-2035 ◽  
Author(s):  
N. Maus ◽  
N. Stuurman ◽  
P.A. Fisher
Keyword(s):  
Nuclear Lamina ◽  
Meiotic Metaphase ◽  
Two Dimensional ◽  
Cell Free Extract ◽  
Free System ◽  
Nuclear Lamin ◽  
A Cell

Stage 14 Drosophila oocytes are arrested in first meiotic metaphase. A cell-free extract of these oocytes catalyzes apparent disassembly of purified Drosophila nuclei as well as of nuclear lamin polymers formed in vitro from isolated interphase lamins. Biochemically, the oocyte extract catalyzes lamin solubilization and phosphorylation as well as characteristic changes in one- and two-dimensional gel mobility. A previously unidentified soluble lamin isoform is easily seen after in vitro disassembly. This isoform is detectable but present only in very small quantities in vivo and is apparently derived specifically from one of the two interphase lamin isoforms. Cell-free nuclear lamina disassembly is ATP-dependent and addition of calcium to extracts blocks disassembly as judged both morphologically and biochemically. This system will allow enzymological characterization of cell-free lamina disassembly as well as molecular analysis of specific Drosophila mutants.

scholarly journals Evaluation and Estimation of Entrance Skin Dose in Patients During Diagnostic and Interventional Radiology Procedures

2004 ◽  
Vol 60 (1) ◽  
pp. 126-135 ◽  
Author(s):  
HIROJI IIDA ◽  
JUNSEI HORII ◽  
MITSUHIRO CHABATAKE ◽  
ETSUROU TAKA ◽  
MITSURU SHIMUIZU ◽  
...  
Keyword(s):  
Interventional Radiology ◽  
Skin Dose ◽  
Entrance Skin Dose ◽  
Interventional Radiology Procedures
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