SU-E-T-52: Independent Dose Verification System for Spot Scanning Proton Therapy

2012 ◽  
Vol 39 (6Part10) ◽  
pp. 3714-3714
Author(s):  
Y Li ◽  
M Lii ◽  
H Li ◽  
M Taylor ◽  
X Li ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Dose Verification ◽  
Spot Scanning ◽  
Verification System

scholarly journals EP-1583: An automated Monte Carlo plan verification system for spot-scanning proton therapy

2016 ◽  
Vol 119 ◽  
pp. S735
Author(s):  
J. Richardson ◽  
A. Aitkenhead ◽  
T. Lomax ◽  
S. Safai ◽  
F. Albertini ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Spot Scanning ◽  
Verification System

scholarly journals Empirical quenching correction in radiochromic silicone-based three-dimensional dosimetry of spot-scanning proton therapy

2021 ◽  
Vol 18 ◽  
pp. 11-18
Author(s):  
Lia Barbosa Valdetaro ◽  
Ellen Marie Høye ◽  
Peter Sandegaard Skyt ◽  
Jørgen Breede Baltzer Petersen ◽  
Peter Balling ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Three Dimensional ◽  
Spot Scanning

scholarly journals Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy

2016 ◽  
Vol 17 (5) ◽  
pp. 366-376 ◽  
Author(s):  
Xin Wang ◽  
Falk Poenisch ◽  
Narayan Sahoo ◽  
Ronald X. Zhu ◽  
MingFwu Lii ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Proton Therapy ◽  
Neutron Dose ◽  
Spot Scanning

PO-1417: A GPU Monte Carlo to support clinical routine in a compact spot scanning proton therapy system

2020 ◽  
Vol 152 ◽  
pp. S752-S753
Author(s):  
J. Gajewski ◽  
A. Schiavi ◽  
N. Krah ◽  
V. Patera ◽  
G. Vilches-Freixas ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Clinical Routine ◽  
Spot Scanning

scholarly journals Fast MCsquare-Based Independent Dose Verification Platform for Pencil Beam Scanning Proton Therapy

2021 ◽  
Vol 20 ◽  
pp. 153303382110330
Author(s):  
Chunbo Liu ◽  
Meng Wei Ho ◽  
Jiyeon Park ◽  
Wen Chien Hsi ◽  
Xiaoying Liang ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Treatment Plan ◽  
Dose Calculation ◽  
Pencil Beam ◽  
Dose Verification ◽  
Beam Scanning ◽  
Water Phantom ◽  
Pencil Beam Scanning ◽  
The Absolute ◽  
Clinical Cases

Purpose: To commission MCsquare (a multi-cores CPU-based dose calculation engine) for pencil beam scanning (PBS) proton therapy, integrate it into RayStation treatment plan system (TPS) to create a dedicated platform for fast independent dose verification. Method: A MCsquare-based independent dose verification platform (MC2InRS) was developed to realize automatic dose re-calculation for clinical use, including data preparation, dose calculation, 2D/3D gamma analysis. MCsquare was commissioned based on in-air lateral dose profiles, integrated depth dose, and the absolute dose of different beam energies for Proteus®ONE. MC2InRS was validated with measurement data using various targets and depths in a water phantom. This study also investigated 15 clinical cases to demonstrate the feasibility and effectiveness of MC2InRS platform in clinic practice. Results: Between simulation and measurement, the distal range differences at 80% (R80) and 20% (R20) dose levels for each energy were below 0.05 mm, and 0.1 mm, respectively, and the absolute dose differences were below 0.5%. 29 out of 36 QA planes reached a 100% gamma passing rate (GPR) for 2%/2mm criteria, and a minimum of 98.3% gamma was obtained in water phantom between simulation and measurement. For the 15 clinical cases investigated, the average 2D GPR (2%/2mm) was 95.4%, 99.3% for MCsquare vs. measurement, MCsquare vs. TPS, respectively. The average 3D GPR (2%/2mm) was 98.9%, 95.3% for MCsquare vs. TPS in water, and computed tomography (CT), respectively. Conclusion: MC2InRS, a fast, independent dose verification platform, has been developed to perform dose verification with high accuracy and efficiency for Pencil Bream Scanning (PBS). Its potential to be applied in routine clinical practice has also been discussed.

scholarly journals Clinical Implementation of Proton Therapy Using Pencil-Beam Scanning Delivery Combined With Static Apertures

2021 ◽  
Vol 11 ◽  
Author(s):  
Christian Bäumer ◽  
Sandija Plaude ◽  
Dalia Ahmad Khalil ◽  
Dirk Geismar ◽  
Paul-Heinz Kramer ◽  
...  
Keyword(s):  
At Risk ◽  
Proton Therapy ◽  
Target Volume ◽  
Delivery Mode ◽  
Pencil Beam ◽  
Clinical Implementation ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Spot Scanning ◽  
The Mean

Proton therapy makes use of the favorable depth-dose distribution with its characteristic Bragg peak to spare normal tissue distal of the target volume. A steep dose gradient would be desired in lateral dimensions, too. The widespread spot scanning delivery technique is based, however, on pencil-beams with in-air spot full-widths-at-half-maximum of typically 1 cm or more. This hampers the sparing of organs-at-risk if small-scale structures adjacent to the target volume are concerned. The trimming of spot scanning fields with collimating apertures constitutes a simple measure to increase the transversal dose gradient. The current study describes the clinical implementation of brass apertures in conjunction with the pencil-beam scanning delivery mode at a horizontal, clinical treatment head based on commercial hardware and software components. Furthermore, clinical cases, which comprised craniopharyngiomas, re-irradiations and ocular tumors, were evaluated. The dosimetric benefits of 31 treatment plans using apertures were compared to the corresponding plans without aperture. Furthermore, an overview of the radiation protection aspects is given. Regarding the results, robust optimization considering range and setup uncertainties was combined with apertures. The treatment plan optimizations followed a single-field uniform dose or a restricted multi-field optimization approach. Robustness evaluation was expanded to account for possible deviations of the center of the pencil-beam delivery and the mechanical center of the aperture holder. Supplementary apertures improved the conformity index on average by 15.3%. The volume of the dose gradient surrounding the PTV (evaluated between 80 and 20% dose levels) was decreased on average by 17.6%. The mean dose of the hippocampi could be reduced on average by 2.9 GyRBE. In particular cases the apertures facilitated a sparing of an organ-at-risk, e.g. the eye lens or the brainstem. For six craniopharyngioma cases the inclusion of apertures led to a reduction of the mean dose of 1.5 GyRBE (13%) for the brain and 3.1 GyRBE (16%) for the hippocampi.

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