TH-E-BRB-03: Potential for a Monte Carlo Based Treatment Planning System to Replace Patient Specific QA Measurements in a Large University Hospital Setting

2011 ◽  
Vol 38 (6Part35) ◽  
pp. 3866-3866
Author(s):  
E Soisson ◽  
A Alexander ◽  
L Comeau ◽  
J Seuntjens
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Hospital Setting ◽  
University Hospital ◽  
Planning System ◽  
Treatment Planning System ◽  
Patient Specific ◽  
Patient Specific Qa

scholarly journals A benchmarking method to evaluate the accuracy of a commercial proton monte carlo pencil beam scanning treatment planning system

2017 ◽  
Vol 18 (2) ◽  
pp. 44-49 ◽  
Author(s):  
Liyong Lin ◽  
Sheng Huang ◽  
Minglei Kang ◽  
Petri Hiltunen ◽  
Reynald Vanderstraeten ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Planning System ◽  
Treatment Planning System ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning

scholarly journals Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Naonori Hu ◽  
Hiroki Tanaka ◽  
Ryo Kakino ◽  
Syuushi Yoshikawa ◽  
Mamoru Miyao ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Neutron Capture ◽  
Gamma Ray ◽  
Dose Calculation ◽  
Planning System ◽  
Treatment Planning System ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Monte Carlo Dose Calculation

AbstractBoron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement under the national health insurance as of June 2020. A new treatment planning system for clinical BNCT has been developed by Sumitomo Heavy Industries, Ltd. (Sumitomo), NeuCure® Dose Engine. To safely implement this system for clinical use, the simulated neutron flux and gamma ray dose rate inside a water phantom was compared against experimental measurements. Furthermore, to validate and verify the new planning system, the dose distribution inside an anthropomorphic head phantom was compared against a BNCT treatment planning system SERA and an in-house developed Monte Carlo dose calculation program. The simulated results closely matched the experimental results, within 5% for the thermal neutron flux and 10% for the gamma ray dose rate. The dose distribution inside the head phantom closely matched with SERA and the in-house developed dose calculation program, within 3% for the tumour and a difference of 0.3 Gyw for the brain.

scholarly journals An Integrated Framework Based on Full Monte Carlo Simulations for Double-Scattering Proton Therapy

2019 ◽  
Vol 6 (2) ◽  
pp. 31-41
Author(s):  
Jiankui Yuan ◽  
David Mansur ◽  
Min Yao ◽  
Tithi Biswas ◽  
Yiran Zheng ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Therapy ◽  
Treatment Plan ◽  
Planning System ◽  
Treatment Planning System ◽  
Patient Specific ◽  
Double Scattering ◽  
Integrated Framework ◽  
End To End ◽  
Clinical Cases

ABSTRACT Purpose: We developed an integrated framework that employs a full Monte Carlo (MC) model for treatment-plan simulations of a passive double-scattering proton system. Materials and Methods: We have previously validated a virtual machine source model for full MC proton-dose calculations by comparing the percentage of depth-dose curves, spread-out Bragg peaks, and lateral profiles against measured commissioning data. This study further expanded our previous work by developing an integrate framework that facilitates its clinical use. Specifically, we have (1) constructed patient-specific applicator and compensator numerically from the plan data and incorporated them into the beamline, (2) created the patient anatomy from the computed tomography image and established the transformation between patient and machine coordinate systems, and (3) developed a graphical user interface to ease the whole process from importing the treatment plan in the Digital Imaging and Communications in Medicine format to parallelization of the MC calculations. End-to-end tests were performed to validate the functionality, and 3 clinical cases were used to demonstrate clinical utility of the framework. Results: The end-to-end tests demonstrated that the framework functioned correctly for all tested functionality. Comparisons between the treatment planning system calculations and MC results in 3 clinical cases revealed large dose difference up to 17%, especially in the beam penumbra and near the end of beam range. The discrepancy likely originates from a variety of sources, such as the dose algorithms, modeling of the beamline, and the dose metric. The agreement for other regions was acceptable. Conclusion: An integrated framework was developed for full MC simulations of double-scattering proton therapy. It can be a valuable tool for dose verification and plan evaluation.

Clinical use of a commercial Monte Carlo treatment planning system for electron beams

2005 ◽  
Vol 50 (5) ◽  
pp. 1029-1034 ◽  
Author(s):  
J E Cygler ◽  
C Lochrin ◽  
G M Daskalov ◽  
M Howard ◽  
R Zohr ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Electron Beams ◽  
Planning System ◽  
Treatment Planning System ◽  
Clinical Use
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