MO-D-BRB-10: Optical Surface Imaging for Online Rotation Correction and Real-Time Motion Monitoring with Threshold Gating for Frameless Cranial Stereotactic Radiosurgery

2011 ◽  
Vol 38 (6Part26) ◽  
pp. 3711-3711 ◽  
Author(s):  
G Li ◽  
A Ballangrud ◽  
L Kuo ◽  
H Kang ◽  
A Kirov ◽  
...  
2009 ◽  
Vol 36 (6Part17) ◽  
pp. 2648-2648 ◽  
Author(s):  
L Cerviño ◽  
W Song ◽  
J Wang ◽  
J Lawson ◽  
T Pawlicki ◽  
...  

Author(s):  
Lei Zhang ◽  
Sarath Vijayan ◽  
Sheng Huang ◽  
Yulin Song ◽  
Tianfang Li ◽  
...  

2013 ◽  
Vol 40 (11) ◽  
pp. 111712 ◽  
Author(s):  
Rodney D. Wiersma ◽  
S. L. Tomarken ◽  
Zachary Grelewicz ◽  
Andrew H. Belcher ◽  
Hyejoo Kang

2011 ◽  
Vol 38 (7) ◽  
pp. 3981-3994 ◽  
Author(s):  
Guang Li ◽  
Åse Ballangrud ◽  
Li Cheng Kuo ◽  
Hyejoo Kang ◽  
Assen Kirov ◽  
...  

Neurosurgery ◽  
2012 ◽  
Vol 71 (4) ◽  
pp. 844-852 ◽  
Author(s):  
Hubert Pan ◽  
Laura I. Cerviño ◽  
Todd Pawlicki ◽  
Steve B. Jiang ◽  
John Alksne ◽  
...  

Abstract BACKGROUND: Frameless stereotactic radiosurgery is commonly used to treat intracranial metastases, but mask-based immobilization can be uncomfortable for patients. OBJECTIVE: To describe the clinical outcomes using a novel real-time, frameless, surface imaging--guided radiosurgery (SIG-RS) technique to treat brain metastases. METHODS: Data were prospectively gathered for 44 consecutive patients totaling 115 intracranial metastases treated with SIG-RS in a median of 1 fraction (range, 1–5) to a median dose of 20 Gy (range, 15-30 Gy). Local control, regional control, and overall survival were estimated by the Kaplan-Meier method. RESULTS: Median follow-up for all patients was 6.0 months (range, 0.3-21.6 months), with 31 of 44 (70%) deceased at the time of analysis. The 35 patients (80%) with follow-up imaging totaled 88 lesions evaluable for local control. Actuarial 6- and 12-month local control was 90% (95% confidence interval, 82–98) and 76% (95% confidence interval, 60–91), respectively. Regional failure was observed in 16 patients (46%). The median actuarial overall survival was 7.7 months (95% confidence interval, 5.7-9.7). Analysis of the subset of 22 patients (55 lesions) who received SIG-RS alone (no prior treatment) in a single fraction yielded comparable clinical outcomes. Grade 3 or greater toxicity occurred in 4 patients (9%). The median treatment time from beam on to beam off was 15 minutes (range, 3-36 minutes). CONCLUSION: SIG-RS for treating intracranial metastases can produce clinical outcomes comparable to those with conventional frame-based and frameless stereotactic radiosurgery techniques while providing greater patient comfort with an open-faced mask and fast treatment times.


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