SU-E-T-340: Dose Enhancement Due to Backscattered Electrons of Gold Nanoparticle: Size and Shape Dependency Study by Thermoluminescent Dosimetry

2011 ◽  
Vol 38 (6Part15) ◽  
pp. 3565-3565
Author(s):  
T Marques ◽  
G Barbi ◽  
O Baffa ◽  
P Nicolucci
Nanoscale ◽  
2016 ◽  
Vol 8 (15) ◽  
pp. 7992-8007 ◽  
Author(s):  
Jingchao Li ◽  
Jia'En Jasmine Li ◽  
Jing Zhang ◽  
Xinlong Wang ◽  
Naoki Kawazoe ◽  
...  

2017 ◽  
Vol 28 (6) ◽  
pp. 1791-1800 ◽  
Author(s):  
Jun Yue ◽  
Timothy Joel Feliciano ◽  
Wenlong Li ◽  
Andrew Lee ◽  
Teri W. Odom

2021 ◽  
Vol 11 (22) ◽  
pp. 10856
Author(s):  
Ngoc Han Huynh ◽  
James C. L. Chow

Heavy atom nanoparticles, such as gold nanoparticles, are proven effective radiosensitizers in radiotherapy to enhance the dose delivery for cancer treatment. This study investigated the effectiveness of cancer cell killing, involving gold nanoparticle in proton radiation, by changing the nanoparticle size, proton beam energy, and distance between the nanoparticle and DNA. Monte Carlo (MC) simulation (Geant4-DNA code) was used to determine the dose enhancement in terms of dose enhancement ratio (DER), when a gold nanoparticle is present with the DNA. With varying nanoparticle size (radius = 15–50 nm), distance between the gold nanoparticle and DNA (30–130 nm), as well as proton beam energy (0.5–25 MeV) based on the simulation model, our results showed that the DER value increases with a decrease of distance between the gold nanoparticle and DNA and a decrease of proton beam energy. The maximum DER (1.83) is achieved with a 25 nm-radius gold nanoparticle, irradiated by a 0.5 MeV proton beam and 30 nm away from the DNA.


2021 ◽  
Vol 171 ◽  
pp. 109638
Author(s):  
Tara Gray ◽  
Nema Bassiri ◽  
Shaquan David ◽  
Devanshi Yogeshkumar Patel ◽  
Sotirios Stathakis ◽  
...  

2011 ◽  
Vol 2 (10) ◽  
pp. 1171-1177 ◽  
Author(s):  
Edward P. O’Brien ◽  
John. E. Straub ◽  
Bernard R. Brooks ◽  
D. Thirumalai

Author(s):  
Gail A. Vinnacombe-Willson ◽  
Naihao Chiang ◽  
Paul S. Weiss ◽  
Sarah H. Tolbert ◽  
Leonardo Scarabelli

2016 ◽  
Vol 110 (3) ◽  
pp. 529a-530a ◽  
Author(s):  
Nicholas C. Fitzkee ◽  
Ailin Wang ◽  
Karen E. Woods ◽  
Randika Perera

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