SU-E-J-74: A Dosimeter for In Vivo Real Time Verification of Intensity Modulated Radiation Therapy

2011 ◽  
Vol 38 (6Part8) ◽  
pp. 3459-3459
Author(s):  
S Price ◽  
A A Silvius ◽  
E W Izaguirre
Keyword(s):  
Radiation Therapy ◽  
Real Time ◽  
Intensity Modulated Radiation Therapy ◽  
Intensity Modulated

An integral quality monitoring system for real-time verification of intensity modulated radiation therapy

2009 ◽  
Vol 36 (12) ◽  
pp. 5420-5428 ◽  
Author(s):  
Mohammad K. Islam ◽  
Bernhard D. Norrlinger ◽  
Jason R. Smale ◽  
Robert K. Heaton ◽  
Duncan Galbraith ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Real Time ◽  
Monitoring System ◽  
Intensity Modulated Radiation Therapy ◽  
Quality Monitoring ◽  
Intensity Modulated ◽  
Integral Quality

An algorithm for real-time dosimetry in intensity-modulated radiation therapy using the radioluminescence signal from Al2O3:C

2006 ◽  
Vol 120 (1-4) ◽  
pp. 7-13 ◽  
Author(s):  
C. E. Andersen ◽  
C. J. Marckmann ◽  
M. C. Aznar ◽  
L. Bøtter-Jensen ◽  
F. Kjær-Kristoffersen ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Real Time ◽  
Intensity Modulated Radiation Therapy ◽  
Intensity Modulated

scholarly journals In vitro and in vivo efficacy of Albendazole Chitosan Microspheres with Intensity-modulated Radiation Therapy in the treatment of spinal echinococcosis

2021 ◽  
Author(s):  
Sibo Wang ◽  
Shan Wang ◽  
Weishan Wang ◽  
Yi Dai ◽  
Zhongpeng Qiu ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Intensity Modulated Radiation Therapy ◽  
Confocal Imaging ◽  
Ultrastructural Changes ◽  
Therapeutic Effects ◽  
Inhibition Rate ◽  
Chitosan Microspheres ◽  
Intensity Modulated

Currently, there is a lack of clinically safe and effective treatment for spinal cystic echinococcosis (CE). Recent studies have shown that albendazole chitosan microspheres (ABZ-CS-MPS) and irradiation have certain anti-abdominal echinococcosis ability, so this study aims to compare the in vitro and in vivo therapeutic effects of ABZ-CS-MPs, Intensity-modulated radiation therapy (IMRT) and the combination therapy on spinal echinococcosis. Firstly, protoscolices were processed by different treatments to evaluate their respective anti-echinococcosis effect by monitoring the viability change of protoscoleces. Then, the apoptotic status of protoscoleces was evaluated by detecting the changes of mitochondrial membrane potential, the expression of apoptosis proteins and the ultrastructural alterations of protoscoleces. After that, we constructed a gerbil model of spinal CE and further applied B-ultrasound and magnetic resonance imaging technology to assess the size of hydatid in vivo. Finally, the cysts were obtained and weighed to compare the inhibition rate in different groups. The combined therapy increased protoscoleces mortality to over 90% after 18 days, which showed the highest scolicidal effect. Moreover, confocal imaging, expression of apoptotic proteins and ultrastructural changes of protoscoleces showed the highest apoptotic rate in this group. In vivo, the combination treatment also exhibited the highest cyst inhibition rate (61.4%). In conclusion, our results showed that ABZ-CS-MPs combined with IMRT could be a new treatment option for spinal CE. We also provided a method to evaluate the growth and metastasis of hydatid in animals with B-ultrasound and MRI imaging technologies.

Sign in / Sign up

Export Citation Format

Share Document