SU-E-I-155: Esophageal Squamous Cell Carcinoma: Relationship Between 18F-FDG PET-CT Maximum Standardized Uptake Value, Metabolic Tumour Volume and TNM Classification

2011 ◽  
Vol 38 (6Part6) ◽  
pp. 3432-3432
Author(s):  
W Zhu ◽  
X Sun ◽  
L Xing ◽  
J Yue ◽  
W Qu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Tnm Classification ◽  
Standardized Uptake Value ◽  
Tumour Volume ◽  
Metabolic Tumour Volume ◽  
Maximum Standardized Uptake Value ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Maximum Standardized Uptake Value in Lymph Nodes Measured by 18F-FDG PET/CT Predicts the Outcome of Patients with Oesophagus Squamous Cell Carcinoma

2020 ◽  
Author(s):  
Wenjia Ren ◽  
Weiwei Chen ◽  
Yun Chen ◽  
Qi Liu ◽  
Dashan Ai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Lymph Nodes ◽  
Fdg Pet ◽  
Standardized Uptake Value ◽  
Maximum Standardized Uptake Value ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Better Than

Abstract Background: To investigate the prognostic value of 18F–fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in esophagus squamous cell carcinoma (ESCC), PET/CT imaging characteristics were explored in the present study.Methods: Baseline PET/CT and clinical characteristics were collected in 125 patients with ESCC treated with radical radiotherapy from 2007–2016. The maximum standardized uptake value (SUVmax) of the primary gross tumour (SUVmax-T) and metastatic lymph node (SUVmax-N) were separately measured using X-tile. Overall survival (OS) and progression free survival (PFS) were estimated according to the Kaplan–Meier method. A multivariate Cox model was used to establish the independent prognostic factors.Results: The gross tumours presented higher 18F-FDG uptake than normal tissues with a median SUVmax-T of 12.5. The OS and PFS did not show significant differences between patients with SUVmax-T ≥ 12.5 and those with SUVmax-T <12.5 (P>0.05). However, patients with SUVmax-N ≥ 11 had a significantly worse OS and PFS than those with SUVmax-N <11 (P<0.05). A weak correlation was observed in SUVmax-T and SUVmax-N. The OS and PFS of patients with PET-negative LNs was significantly better than those with PET-positive LNs. However, the OS and PFS of patients with one or two PET-positive LNs were not significantly better than those with more than two PET-positive LNs. In the univariate analysis, cT stage, positive or negative lymph nodes on the PET-CT image and the SUVmax-N were established as significant prognostic factors for both OS and PFS. In multivariate analysis, SUVmax-N was proved to be an independent predictor for OS and PFS.Conclusions: SUVmax-N, but not SUVmax-T, is an independent prognostic indicator for patients with ESCC.

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