SU-GG-J-104: Inclusion of Effects of Image Registration Errors in Accumulated Dose Distributions

2010 ◽  
Vol 37 (6Part11) ◽  
pp. 3169-3169
Author(s):  
D McQuaid ◽  
G Sharp ◽  
T Bortfeld
2015 ◽  
Vol 14 (1) ◽  
pp. 37-47 ◽  
Author(s):  
Jialu Yu ◽  
Nicholas Hardcastle ◽  
Kyoungkeun Jeong ◽  
Edward T. Bender ◽  
Mark A. Ritter ◽  
...  

2021 ◽  
Author(s):  
Stacy-Lee Annis

The relationship between dose mapped using two mapping methods (energy mapping method and voxel warping method) and registration error was examined. The correlation between the difference in doses mapped using these methods, defined as dose mapping difference (DMD), and landmark distance to agreement for a realistic lung patient plan using registrations of varying accuracy was examined. Results showed no correlation between DMD and landmark error. Further investigation on simple dose mapping geometries revealed a correlation of DMD with fractional volume (FVC) change induced by registration errors. A formula for DMD as a function of FVC was derived. Results of this formula agreed with simulated values of DMD with percentage differences less than 3.5% in regions of uniform dose. However, no agreement was found in regions containing a dose gradient. Further work is required in order to extend this formula to regions of dose gradients and scenarios that emulate realistic deformations.


2013 ◽  
Vol 40 (6Part26) ◽  
pp. 436-436
Author(s):  
H Zhong ◽  
J Kim ◽  
C Glide-Hurst ◽  
I Chetty

2000 ◽  
Vol 93 (supplement_3) ◽  
pp. 208-218 ◽  
Author(s):  
Jonathan P. Knisely ◽  
James E. Bond ◽  
Ning J. Yue ◽  
Colin Studholme ◽  
Alain C. J. de Lotbinière

✓ The purpose of this study was to develop techniques for registering image sets associated with staged or multifraction radiosurgical treatments of large targets with the Leksell gamma knife to transform shot coordinates between treatment sessions and produce cumulative dose distributions and to investigate the theoretical biological effects of such protracted treatments by means of such concepts as the linear—quadratic model and biologically effective dose. An image registration technique based on normalized mutual information was adapted to produce one fused-image study from an imaging series acquired during distinct treatment sessions. A spreadsheet computer program was developed to determine coordinate transformations between the associated stereotactic coordinate systems based on digitized coordinates of fiducial markers appearing on the fused images. Coordinates of shots used during one treatment session could then be transformed to the stereotactic space of another session, and cumulative dose distributions could be computed. The procedure was applied to the two-stage treatment of a giant arteriovenous malformation (AVM). Overall uncertainty in each transformed shot position is approximately 0.7 mm. An effective single-fraction dose (Deff) was defined and computed for the two-stage AVM treatment. The simple summed dose distribution was compared with the Deff distribution. Because dose values differ significantly in overlap regions between the individual distributions, the clinical usefulness of the simple cumulative distribution is dubious. It may be useful for a future update of the GammaPlan treatment planning software to generate effective single-session dose distributions for such cases.


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