SU-GG-I-105: Ultrafast Deformable Image Registration for Potential Adaptive Total Body Irradiation Therapy Using Helical TomoTherapy

2010 ◽  
Vol 37 (6Part4) ◽  
pp. 3125-3125
Author(s):  
M Chao ◽  
J Penagaricano ◽  
E Moros
2017 ◽  
Vol 123 ◽  
pp. S853-S854
Author(s):  
G. Guidi ◽  
N. Maffei ◽  
P. Ceroni ◽  
G.M. Mistretta ◽  
F. Lohr ◽  
...  

2019 ◽  
Vol 19 (1) ◽  
pp. 25-29
Author(s):  
Warit Thongsuk ◽  
Imjai Chitapanarux ◽  
Somsak Wanwilairat ◽  
Wannapha Nobnop

AbstractPurpose:To evaluate changes of accumulated doses from an initial plan in each fraction by deformable image registration (DIR) with daily megavoltage computed tomography (MVCT) images from helical tomotherapy for prostate cancer patients.Materials and methods:The MVCT images of five prostate cancer patients were acquired by using a helical tomotherapy unit before the daily treatment fraction began. All images data were exported to DIR procedures by MIM software, in which the planned kilovoltage computed tomography (kVCT) images were acting as the source images with the daily MVCT acquired as the target images for registration. The automatic deformed structure was used to access the volume variation and daily dose accumulation to each structure. All dose-volume parameters were compared to the initial planned dose.Results:The actual median doses of the planning target volume (PTV) received 70 Gy and 50.4 Gy were decreased at the end of the treatment with an average 1·0 ± 0·67% and 2·1 ± 1·54%, respectively. As regards organs at risk (OARs), the bladder and rectum dose-volume parameters tended to increase from the initial plan. The high-dose regions of the bladder and rectum, however, were decreased from the initial plan at the end of the treatment.Conclusions:The daily actual dose differs from the initial planned dose. The accumulated dose of target tends to be lower than the initial plan, but tends to be higher than the initial plan for the OARs. Therefore, inter-fractional anatomic changes should be considered by the DIR methods, which would be useful as clinically informative and beneficial for adaptive treatment strategies.


2016 ◽  
Vol 43 (11) ◽  
pp. 1376-1377 ◽  
Author(s):  
Ryosuke Takenaka ◽  
Hideomi Yamashita ◽  
Takashi Toya ◽  
Akihiro Haga ◽  
Shino Shibata ◽  
...  

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
HaiYang Wang ◽  
JunQi Liu ◽  
YiFei Pi ◽  
Qi Liu ◽  
Yang Mi ◽  
...  

Abstract Objective To assess the effects of various treatment planning parameters to identify the optimal gap distance for precise two-segment total body irradiation (TBI) using helical tomotherapy (HT) with fixed jaw mode. Methods and materials Data of a treatment plan for 8 acute leukemia patients (height range: 109–130 cm) were analyzed. All patients underwent total-body computed tomography (CT) with 5-mm slice thickness. A lead wire, placed at 10 cm above the patella, was used to mark the boundary between the two segments. Target volumes and organs at risk were delineated using a Varian Eclipse 10.0 physician’s workstation. Different distances between the lead wire and the boundary of the two targets were used. CT images were transferred to the HT workstation to design the treatment plans, by adjusting parameters, including the field width (FW; 2.5 cm, and 5 cm), pitch (0.287 and 0.430), modulation factor (1.8). The plans were superimposed to analyze the dose distributions in the overlap region when varying target gap distances, FWs, pitches to determine the optimal combinations. Results The pitch did not affect the dose distribution in the overlap region. The dose distribution in the overlap region was mostly homogeneous when the target gap distance was equal to the FW. Increased FW diminished the effect of the target gap distance on the heterogeneous index of the overlap region. Conclusions In two-segment TBI treatments by HT with Helix mode, a gap distance equal to the FW may achieve optimal dose distribution in the overlap region.


2021 ◽  
Vol 26 (1) ◽  
pp. 153-158
Author(s):  
Khaled Dibs ◽  
Austin J. Sim ◽  
Jose A. Penagaricano ◽  
Kujtim Latifi ◽  
Genevieve A. Garcia ◽  
...  

2010 ◽  
Vol 37 (6Part15) ◽  
pp. 3185-3185
Author(s):  
M Chao ◽  
J Penagaricano ◽  
Y Yan ◽  
E Moros ◽  
K Gardner ◽  
...  

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