Semiautomatic vessel wall detection and quantification of wall thickness in computed tomography images of human abdominal aortic aneurysms

2010 ◽  
Vol 37 (2) ◽  
pp. 638-648 ◽  
Author(s):  
Judy Shum ◽  
Elena S. DiMartino ◽  
Adam Goldhammer ◽  
Daniel H. Goldman ◽  
Leah C. Acker ◽  
...  
Author(s):  
Judy Shum ◽  
Adam Goldhammer ◽  
Elena DiMartino ◽  
Ender Finol

Quantitative measurements of wall thickness in human abdominal aortic aneurysms (AAAs) may provide useful information to predict rupture risk. Our procedure for estimating wall thickness in AAAs includes medical image segmentation and wall thickness detection. Image segmentation requires identifying and segmenting the luminal and outer wall boundaries of the blood vessels and wall thickness can be calculated by using intensity histograms and neural networks. The goal of this study is to develop an image-based, semi-automated method to trace the contours of the vessel wall and measure the wall thickness of the abdominal aorta from in-vivo, contrast-enhanced, CT images. An algorithm for the lumen and inner wall segmentations, and wall thickness detection was developed and tested on 10 ruptured and 10 unruptured AAAs. Reproducibility and repeatability of the algorithm were determined by comparing manual tracings made by two observers to contours made automatically by the algorithm itself. There was a high correspondence between automatic and manual area measurements for the lumen (r = 0.96) and between users (r = 0.98). Based on statistical analyses, the algorithm tends to underestimate the lumen area when compared to both observers.


Clinics ◽  
2005 ◽  
Vol 60 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Francisco das Chagas de Azevedo ◽  
Antonio Eduardo Zerati ◽  
Roberto Blasbalg ◽  
Nelson Wolosker ◽  
Pedro Puech-Leão

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Yohei Kawatani ◽  
Yoshitsugu Nakamura ◽  
Yujiro Hayashi ◽  
Tetsuyoshi Taneichi ◽  
Yujiro Ito ◽  
...  

Infectious abdominal aortic aneurysms often present with abdominal and lower back pain, but prolonged fever may be the only symptom. Infectious abdominal aortic aneurysms initially presenting with meningitis are extremely rare; there are no reports of their successful treatment. Cases withStreptococcus pneumoniaeas the causative bacteria are even rarer with a higher mortality rate than those caused by other bacteria. We present the case of a 65-year-old man with lower limb weakness and back pain. Examination revealed fever and neck stiffness. Cerebrospinal fluid showed leukocytosis and low glucose levels. The patient was diagnosed with meningitis and bacteremia caused byStreptococcus pneumoniaeand treated with antibiotics. Fever, inflammatory response, and neurologic findings showed improvement. However, abdominal computed tomography revealed an aneurysm not present on admission. Antibiotics were continued, and a rifampicin soaked artificial vascular graft was implanted. Tissue cultures showed no bacteria, and histological findings indicated inflammation with high leukocyte levels. There were no postoperative complications or neurologic abnormalities. Physical examination, blood tests, and computed tomography confirmed there was no relapse over the following 13 months. This is the first reported case of survival of a patient with an infectious abdominal aortic aneurysm initially presenting with meningitis caused byStreptococcus pneumoniae.


Author(s):  
Áine Tierney ◽  
Anthony Callanan ◽  
Tim M. McGloughlin

Cardiovascular disease concerns any disease which affects the heart or blood vessels. Aneurysms account for a significant portion of these cardiovascular diseases. The most common type of aneurysm is abdominal aortic aneurysm (AAA) which affects up to 5% of the population over the age of 55. AAA is a focal balloon like dilation of the terminal aorta that occurs gradually over a span of years [1]. There are approximately 200,000 patients in the US and 500,000 patients worldwide diagnosed with AAA each year [2]. The incidences of AAA’s has increased largely during the past two decades due in part to the aging demographic, the rise in the number of smokers, the introduction of screening programmes and improved diagnostic tools [3].


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