SU-GG-J-57: Comparison of the Residual Error in Treatment Set-Up Using Different Imaging Modalities: A Phantom Study

2008 ◽  
Vol 35 (6Part6) ◽  
pp. 2692-2692 ◽  
Author(s):  
A McNiven ◽  
CL Chin ◽  
AD Vandermeer ◽  
D Moseley
2015 ◽  
Vol 8 (8) ◽  
pp. 3395-3404 ◽  
Author(s):  
J. Danzer ◽  
S. B. Healy ◽  
I. D. Culverwell

Abstract. In this study, a new model was explored which corrects for higher order ionospheric residuals in Global Positioning System (GPS) radio occultation (RO) data. Recently, the theoretical basis of this new "residual ionospheric error model" has been outlined (Healy and Culverwell, 2015). The method was tested in simulations with a one-dimensional model ionosphere. The proposed new model for computing the residual ionospheric error is the product of two factors, one of which expresses its variation from profile to profile and from time to time in terms of measurable quantities (the L1 and L2 bending angles), while the other describes the weak variation with altitude. A simple integral expression for the residual error (Vorob’ev and Krasil’nikova, 1994) has been shown to be in excellent numerical agreement with the exact value, for a simple Chapman layer ionosphere. In this case, the "altitudinal" element of the residual error varies (decreases) by no more than about 25 % between ~10 and ~100 km for physically reasonable Chapman layer parameters. For other simple model ionospheres the integral can be evaluated exactly, and results are in reasonable agreement with those of an equivalent Chapman layer. In this follow-up study the overall objective was to explore the validity of the new residual ionospheric error model for more detailed simulations, based on modeling through a complex three-dimensional ionosphere. The simulation study was set up, simulating day and night GPS RO profiles for the period of a solar cycle with and without an ionosphere. The residual ionospheric error was studied, the new error model was tested, and temporal and spatial variations of the model were investigated. The model performed well in the simulation study, capturing the temporal variability of the ionospheric residual. Although it was not possible, due to high noise of the simulated bending-angle profiles at mid- to high latitudes, to perform a thorough latitudinal investigation of the performance of the model, first positive and encouraging results were found at low latitudes. Furthermore, first application tests of the model on the data showed a reduction in temperature level of the ionospheric residual at 40 km from about −2.2 to −0.2 K.


2015 ◽  
Vol 8 (1) ◽  
pp. 1151-1176 ◽  
Author(s):  
J. Danzer ◽  
S. B. Healy ◽  
I. D. Culverwell

Abstract. In this study, a new model was explored, which corrects for higher order ionospheric residuals in global positioning system (GPS) radio occultation (RO) data. Recently, the theoretical basis of this new "residual ionospheric error model" has been outlined (Healy and Culverwell, 2015). The method was tested in simulations with a one-dimensional model ionosphere. The proposed new model for computing the residual ionospheric error is the product of two factors, one of which expresses its variation from profile-to-profile and from time-to-time in terms of measurable quantities (the L1 and L2 bending angles), the other of which describes the weak variation with altitude. A simple integral expression for the residual error (Vorob’ev and Krasil’nikova, 1994) has been shown to be in excellent numerical agreement with the exact value, for a simple Chapman layer ionosphere. In this case, the "altitudinal" element of the residual error varies (decreases) by no more than about 25% between ~10 and ~100 km for physically reasonable Chapman layer parameters. For other simple model ionospheres the integral can be evaluated exactly, and results are in reasonable agreement with those of an equivalent Chapman layer. In this follow-up study the overall objective was to explore the validity of the new residual ionospheric error model for more detailed simulations, based on modelling through a complex three-dimensional ionosphere. The simulation study was set up, simulating day and night GPS RO profiles for the period of a solar cycle with and without an ionosphere. The residual ionospheric error was studied, the new error model was tested, and temporal and spatial variations of the model were investigated. The model performed well in the simulation study, capturing the temporal variability of the ionospheric residual. Although, it was not possible, due to high noise of the simulated bending angle profiles at mid to high latitudes, to perform a thorough latitudinal investigation of the performance of the model, first positive and encouraging results were found at low latitudes. Furthermore, first application tests of the model on the data showed a reduction on temperature level of the ionospheric residual at 40 km from about −2.2 to −0.2 K.


2009 ◽  
Vol 8 (4) ◽  
pp. 177-184 ◽  
Author(s):  
D. Willis ◽  
C. Fox ◽  
A. Haworth ◽  
A. Rolfo ◽  
A. Herschtal ◽  
...  

AbstractAccurate patient positioning is vitally important in intensity modulated radiation therapy (IMRT) for head and neck (H&N) cancer. The introduction of kilovoltage (kV) on-board imaging (OBI) at our centre was anticipated to improve the accuracy and efficiency of H&N IMRT patient position verification over traditional megavoltage (MV) electronic portal imaging (EPI). This study compares these imaging systems with a phantom accuracy study and retrospective analysis of imaging workload in H&N IMRT at our centre. Six therapists performed online evaluation of phantom images, and residual positional errors for each system were recorded. The largest residual error was 1 mm for OBI and 3 mm for EPI. The estimated improvement in residual error in OBI over EPI was 0.57 mm (95% confidence interval 0.33–0.81 mm), suggesting treatment staff would be better able to detect set-up deviations with OBI. Electronic treatment records of 20 H&N IMRT patients (10 verified daily with MV EPI and 10 with kV OBI) were analysed. Mean imaging session duration was 9.51 min for EPI and 9.76 min for OBI. Analysis found no evidence of an effect on duration due to the imaging system used for this subset of patients (p = 0.664).


Author(s):  
Marie T. Krüger ◽  
Bálint Várkuti ◽  
Jörg Achinger ◽  
Volker A. Coenen ◽  
Thomas Prokop ◽  
...  

Deep brain stimulation (DBS) is a complex surgical procedure that requires detailed anatomical knowledge. In many fields of neurosurgery navigation systems are used to display anatomical structures during an operation to aid performing these surgeries. In frame-based DBS, the advantage of visualization has not yet been evaluated during the procedure itself. In this study, we added live visualization to a frame-based DBS system, using a standard navigation system and investigated its accuracy and potential use in DBS surgery. As a first step, a phantom study was conducted to investigate the accuracy of the navigation system in conjunction with a frame-based approach. As a second step, 5 DBS surgeries were performed with this combined approach. Afterwards, 3 neurosurgeons and 2 neurologists with different levels of experience evaluated the potential use of the system with a questionnaire. Moreover, the additional personnel, costs and required set up time were noted and compared to 5 consecutive standard procedures. In the phantom study, the navigation system showed an inaccuracy of 2.1 mm (mean SD 0.69 mm). In the questionnaire, a mean of 9.4/10 points was awarded for the use of the combined approach as a teaching tool, a mean of 8.4/10 for its advantage in creating a 3-dimensional (3-D) map and a mean of 8/10 points for facilitating group discussions. Especially neurosurgeons and neurologists in training found it useful to better interpret clinical results and side effects (mean 9/10 points) and neurosurgeons appreciated its use to better interpret microelectrode recordings (mean 9/10 points). A mean of 6/10 points was awarded when asked if the benefits were worth the additional efforts. Initially 2 persons, then one additional person was required to set up the system with no relevant added time or costs. Using a navigation system for live visualization during frame-based DBS surgery can improve the understanding of the complex 3-D anatomy and many aspects of the procedure itself. For now, we would regard it as an excellent teaching tool rather than a necessity to perform DBS surgeries.


Author(s):  
T. G. Naymik

Three techniques were incorporated for drying clay-rich specimens: air-drying, freeze-drying and critical point drying. In air-drying, the specimens were set out for several days to dry or were placed in an oven (80°F) for several hours. The freeze-dried specimens were frozen by immersion in liquid nitrogen or in isopentane at near liquid nitrogen temperature and then were immediately placed in the freeze-dry vacuum chamber. The critical point specimens were molded in agar immediately after sampling. When the agar had set up the dehydration series, water-alcohol-amyl acetate-CO2 was carried out. The objectives were to compare the fabric plasmas (clays and precipitates), fabricskeletons (quartz grains) and the relationship between them for each drying technique. The three drying methods are not only applicable to the study of treated soils, but can be incorporated into all SEM clay soil studies.


Author(s):  
T. Gulik-Krzywicki ◽  
M.J. Costello

Freeze-etching electron microscopy is currently one of the best methods for studying molecular organization of biological materials. Its application, however, is still limited by our imprecise knowledge about the perturbations of the original organization which may occur during quenching and fracturing of the samples and during the replication of fractured surfaces. Although it is well known that the preservation of the molecular organization of biological materials is critically dependent on the rate of freezing of the samples, little information is presently available concerning the nature and the extent of freezing-rate dependent perturbations of the original organizations. In order to obtain this information, we have developed a method based on the comparison of x-ray diffraction patterns of samples before and after freezing, prior to fracturing and replication.Our experimental set-up is shown in Fig. 1. The sample to be quenched is placed on its holder which is then mounted on a small metal holder (O) fixed on a glass capillary (p), whose position is controlled by a micromanipulator.


Author(s):  
O.L. Krivanek ◽  
J. TaftØ

It is well known that a standing electron wavefield can be set up in a crystal such that its intensity peaks at the atomic sites or between the sites or in the case of more complex crystal, at one or another type of a site. The effect is usually referred to as channelling but this term is not entirely appropriate; by analogy with the more established particle channelling, electrons would have to be described as channelling either through the channels or through the channel walls, depending on the diffraction conditions.


Author(s):  
David C. Joy ◽  
Dennis M. Maher

High-resolution images of the surface topography of solid specimens can be obtained using the low-loss technique of Wells. If the specimen is placed inside a lens of the condenser/objective type, then it has been shown that the lens itself can be used to collect and filter the low-loss electrons. Since the probeforming lenses in TEM instruments fitted with scanning attachments are of this type, low-loss imaging should be possible.High-resolution, low-loss images have been obtained in a JEOL JEM 100B fitted with a scanning attachment and a thermal, fieldemission gun. No modifications were made to the instrument, but a wedge-shaped, specimen holder was made to fit the side-entry, goniometer stage. Thus the specimen is oriented initially at a glancing angle of about 30° to the beam direction. The instrument is set up in the conventional manner for STEM operation with all the lenses, including the projector, excited.


Author(s):  
T.S. Savage ◽  
R. Ai ◽  
D. Dunn ◽  
L.D. Marks

The use of lasers for surface annealing, heating and/or damage has become a routine practice in the study of materials. Lasers have been closely looked at as an annealing technique for silicon and other semiconductors. They allow for local heating from a beam which can be focused and tuned to different wavelengths for specific tasks. Pulsed dye lasers allow for short, quick bursts which can allow the sample to be rapidly heated and quenched. This short, rapid heating period may be important for cases where diffusion of impurities or dopants may not be desirable.At Northwestern University, a Candela SLL - 250 pulsed dye laser, with a maximum power of 1 Joule/pulse over 350 - 400 nanoseconds, has been set up in conjunction with a Hitachi UHV-H9000 transmission electron microscope. The laser beam is introduced into the surface science chamber through a series of mirrors, a focusing lens and a six inch quartz window.


Author(s):  
K.-H. Herrmann ◽  
E. Reuber ◽  
P. Schiske

Aposteriori deblurring of high resolution electron micrographs of weak phase objects can be performed by holographic filters [1,2] which are arranged in the Fourier domain of a light-optical reconstruction set-up. According to the diffraction efficiency and the lateral position of the grating structure, the filters permit adjustment of the amplitudes and phases of the spatial frequencies in the image which is obtained in the first diffraction order.In the case of bright field imaging with axial illumination, the Contrast Transfer Functions (CTF) are oscillating, but real. For different imageforming conditions and several signal-to-noise ratios an extensive set of Wiener-filters should be available. A simple method of producing such filters by only photographic and mechanical means will be described here.A transparent master grating with 6.25 lines/mm and 160 mm diameter was produced by a high precision computer plotter. It is photographed through a rotating mask, plotted by a standard plotter.


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