TH-C-L100J-09: Noninvasive Evaluation of Early Radiation-Induced Pulmonary Inflammation Via [11C]-PK11195 Based PET Imaging

2007 ◽  
Vol 34 (6Part22) ◽  
pp. 2623-2623 ◽  
Author(s):  
Z Liu ◽  
E Armour ◽  
E Ford ◽  
M Pomper ◽  
J Wong
Keyword(s):  
Pet Imaging ◽  
Pulmonary Inflammation ◽  
Noninvasive Evaluation ◽  
Radiation Induced ◽  
Early Radiation

Early Radiation-induced Leiomyosarcoma after Right Mastectomy in an 83-year old Woman

2020 ◽  
Vol 92 (5-6) ◽  
pp. 186-188
Author(s):  
Miltiadis Badagionis ◽  
S. Lainas ◽  
D. Sekadakis ◽  
V. Gkanis ◽  
P. Chortis ◽  
...  
Keyword(s):  
Radiation Induced ◽  
Early Radiation

scholarly journals Effect of ozone oxidative preconditioning in preventing early radiation-induced lung injury in rats

2013 ◽  
Vol 46 (9) ◽  
pp. 789-796 ◽  
Author(s):  
B.H. Bakkal ◽  
F.A. Gultekin ◽  
B. Guven ◽  
U.O. Turkcu ◽  
S. Bektas ◽  
...  
Keyword(s):  
Lung Injury ◽  
Radiation Induced ◽  
Early Radiation

scholarly journals Early Radiation-Induced Sarcoma in an Adolescent Treated for Relapsed Hodgkin Lymphoma with Nivolumab

Medicina ◽  
2020 ◽  
Vol 56 (4) ◽  
pp. 155
Author(s):  
Lukas Šalaševičius ◽  
Goda Elizabeta Vaitkevičienė ◽  
Ramunė Pasaulienė ◽  
Rosita Kiudelienė ◽  
Ernesta Ivanauskaitė-Didžiokienė ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Correct Diagnosis ◽  
Secondary Malignancy ◽  
Drug Resistant ◽  
Classic Hodgkin Lymphoma ◽  
Pet Ct ◽  
Radiation Induced ◽  
Early Radiation ◽  
Tumor Biopsies ◽  
Pet Ct Scan

Radiation-induced sarcoma (RIS) has been reported as a late secondary malignancy following radiotherapy for various types of cancer with a median latency of 10 years. We describe an early RIS that developed in an adolescent within three years of treatment (including PD-L1 check-point inhibitor Nivolumab) of a relapsed classic Hodgkin lymphoma (HL) and was diagnosed post-mortem. The patient died of the progressive RIS that was misleadingly assumed to be a resistant HL based on the positive PET/CT scan. Repetitive tumor biopsies are warranted in cases of aggressive and multi-drug resistant HL to validate imaging findings, ensure correct diagnosis and avoid overtreatment.

Complications of radio- and radiochemotherapy in patients undergoing major salivary gland cancer surgery

2019 ◽  
Vol 73 (3) ◽  
pp. 26-31
Author(s):  
Izabela Kordzińska-Cisek ◽  
Ludmiła Grzybowska-Szatkowska
Keyword(s):  
Overall Survival ◽  
Salivary Gland ◽  
Subcutaneous Tissue ◽  
Tnm Classification ◽  
Healing Time ◽  
Salivary Gland Cancer ◽  
Major Salivary Gland ◽  
Radiation Induced ◽  
Early Radiation ◽  
Induced Reaction

Purpose: The aim of this retrospective study was to present the prevalence of early and late radiation-induced reaction and factors affecting its formation and severity in patients after adjuvant radio- or radiochemotherapy in salivary gland cancer. Material and methods: A total of 113 patients with early and 91 with late radiation-induced reaction, irradiated in 2006-2016 were enrolled in the study. The frequency of acute mucosal radiation-induced reaction, time of onset, intensity, healing time, as well as the incidence of late radiation-induced reaction from the skin and subcutaneous tissue were analyzed. Factors that could influence the development and intensity of reaction were identified. Results: Acute severity and the presence of late radiation-induced reaction do not affect overall survival. Dosage in the tumor bed site, as well as the dosage in the nodal region, affect the severity of the acute radiation-induced mucosal reaction. The severity of the early radiation-induced reaction is higher in men, more advanced patients (higher T and N+ in TNM classification), irradiated into a larger area, and those in whom two-dimensional planning and complementary chemoradiotherapy were applied. The late reaction of the skin and subcutaneous tissue was dominated by patients irradiated in the nodal regions and those with a higher intensity of early radiation-induced reaction. Conclusions: Supplementary radiotherapy or radiochemotherapy in salivary gland cancer is associated with acceptable toxicity which has no effect on overall survival.

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