SU-FF-T-426: Treatment Planning Comparison of Dynamic Multileaf Collimation and Helical Tomotherapy for Spinal Cord Sparing in Head and Neck Re-Irradiation

2007 ◽  
Vol 34 (6Part14) ◽  
pp. 2499-2500
Author(s):  
R Popple ◽  
I Brezovich ◽  
J Duan ◽  
S Spencer
2008 ◽  
Vol 35 (6Part16) ◽  
pp. 2834-2835
Author(s):  
M Moldovan ◽  
T Lee ◽  
C Chu ◽  
K Hogstrom ◽  
R Fields ◽  
...  

2013 ◽  
Vol 57 (4) ◽  
pp. 503-511 ◽  
Author(s):  
Tomasz Piotrowski ◽  
Joanna Kaźmierska ◽  
Adam Sokołowski ◽  
Małgorzata Skórska ◽  
Agata Jodda ◽  
...  

2013 ◽  
Vol 106 ◽  
pp. S258
Author(s):  
D. Van Gestel ◽  
G. De Kerf ◽  
W. Crijns ◽  
F. Van den Heuvel ◽  
B. De Ost ◽  
...  

2010 ◽  
Vol 35 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Claus Yang ◽  
Tianxiao Liu ◽  
Richard L. Jennelle ◽  
Janice K. Ryu ◽  
Srinivasan Vijayakumar ◽  
...  

Author(s):  
Yashaswini B. R. ◽  
Kumara Swamy

Background: This study was conducted to compare dosimetric parameters and dose to specific organs at risk (spinal cord and parotids) between intensity modulated radiation therapy (IMRT) and helical tomotherapy (HT) in head and neck squamous cell carcinomas (HNSCC).Methods: Thirty patients with histologically proven HNSCC were treated with chemo radiotherapy, to a dose of 60-70 Gray in 30-35 fractions. This study consists of two arms; IMRT arm and tomotherapy arm. Fifteen consecutive patients treated under IMRT and 15 patients were treated under helical tomotherapy, along with concurrent chemotherapy. PTV1 encompasses low risk planning target volume (PTV) which receives 50 Gy; PTV2 encompasses intermediate risk PTV which receives 54-60 Gy and PTV3 encompasses high risk PTV which receives 66-70 Gy. After completion of planning, dose to the organs at risk (OARs) and targets, homogeneity index and conformity index were evaluated, and tabulated.Results: On evaluation of plans we found that V95% in PTV1, PTV2 and PTV3 were 91.82%, 96.85% and 90.67% respectively for IMRT and 99.25%, 99.68% and 99.73% respectively for tomotherapy. For PTV3, V110% was 0.11% for IMRT and 0.01% for tomotherapy. Homogeneity index in IMRT arm was 0.285 and it was 0.206 in tomotherapy arm. Conformity index was found to be 1.04 for IMRT plans and 1.06 for tomotherapy plans. When mean dose to contra lateral parotids was evaluated, it was 26.91 Gy in IMRT arm and 25.97 Gy in tomotherapy arm. Max dose to spinal cord was better in tomotherapy (43.07 Gy in IMRT and 34.41 Gy in tomotherapy).Conclusions: There was statistically significant reduction in spinal cord maximum dose and point doses in tomotherapy plans compared to IMRT plans. The decrease in spinal cord dose can increase the tolerance reserve which can be useful in dose escalation or re-irradiation if required. There was also decrease in contra lateral parotid doses (not statistically significant). There was significant improvement in V95% in tomotherapy arm compared to IMRT arm, indicating the significantly superior coverage of target volumes in helical tomotherapy plans compared to IMRT plans. V110% (hot spots) inside the target was very minimal in tomotherapy arm compared to IMRT arm. Conformity index, homogeneity index between two arms were comparable.


2018 ◽  
Vol 24 (1) ◽  
pp. 25-31
Author(s):  
Noushin Hassan Pour ◽  
Alireza Farajollahi ◽  
Masoud Jamali ◽  
Ahad Zeinali ◽  
Amir Ghasemi Jangjou

AbstractIntroduction: Due to the effect of radiation on both the tumor and the surrounding normal tissues, the side effects of radiation in normal tissues are expected. One of the important complications in the head and neck radiotherapy is the doses reached to the larynx and spinal cord of patients with non-laryngeal head and neck tumors.Materials and Methods: In this study, CT scan images of 25 patients with non-laryngeal tumors including; lymph nodes, tongue, oropharynx and nasopharynx were used. A three-field and a four-field treatment planning with and without laryngeal shield in 3D CRT technique were planned for each patient. Subsequently, the values of Dmin, Dmean, Dmax and Dose Volume Histogram from the treatment planning system and NTCP values of spinal cord and larynx were calculated with BIOPLAN and MATLAB software for all patients.Results: Statistical results showed that mean values of doses of larynx in both three and four-field methods were significantly different between with and without shield groups. Comparison of absorbed dose didn’t show any difference between the three and four field methods (P>0.05). Using Shield, just the mean and minimum doses of spinal cord decreased in both three and four fields. The NTCP of the spinal cord and larynx by three and four-field methods with shield in the LKB and EUD models significantly are less than that of the three and four fields without shields, and in the four-field method NTCP of larynx is less than three radiation field.Conclusion: The results of this study indicate that there is no significant difference in doses reached to larynx and spinal cord between the treatments techniques, but laryngeal shield reduce dose and NTCP values in larynx considerably.


1998 ◽  
Vol 47 (2) ◽  
pp. 185-189 ◽  
Author(s):  
Mary Kaye Martel ◽  
Avraham Eisbruch ◽  
Theodore S Lawrence ◽  
Benedick A Fraass ◽  
Randall K Ten Haken ◽  
...  

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