Spatial autocorrelation and mean intercept length analysis of trabecular bone anisotropy applied toin vivomagnetic resonance imaging

2007 ◽  
Vol 34 (3) ◽  
pp. 1110-1120 ◽  
Author(s):  
Michael J. Wald ◽  
Branimir Vasilic ◽  
Punam K. Saha ◽  
Felix W. Wehrli
Keyword(s):  
Spatial Autocorrelation ◽  
Trabecular Bone ◽  
Resonance Imaging ◽  
Length Analysis ◽  
Mean Intercept Length

scholarly journals Trabecular Bone Assessment Using Magnetic-Resonance Imaging: A Pilot Study

2020 ◽  
Vol 17 (24) ◽  
pp. 9282
Author(s):  
Lauren Bohner ◽  
Pedro Tortamano ◽  
Norbert Meier ◽  
Felix Gremse ◽  
Johannes Kleinheinz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Trabecular Bone ◽  
Volume Fraction ◽  
Bone Volume ◽  
Control Group ◽  
Resonance Imaging ◽  
Voxel Size ◽  
Trabecular Thickness ◽  
Spin Echo Sequence

The aim of this study was to assess trabecular bone morphology via magnetic-resonance imaging (MRI) using microcomputed tomography (µCT) as the control group. Porcine bone samples were scanned with T1-weighted turbo spin echo sequence imaging, using TR 25 ms, TE 3.5 ms, FOV 100 × 100 × 90, voxel size 0.22 × 0.22 × 0.50 mm, and scan time of 11:18. µCT was used as the control group with 80 kV, 125 mA, and a voxel size of 16 µm. The trabecular bone was segmented on the basis of a reference threshold value and morphological parameters. Bone volume (BV), Bone-volume fraction (BvTv), Bone specific surface (BsBv), trabecular thickness (TbTh), and trabecular separation (TbSp) were evaluated. Paired t-test and Pearson correlation test were performed at p = 0.05. MRI overestimated BV, BvTv, TbTh, and TbSp values. BsBv was the only parameter that was underestimated by MRI. High statistical correlation (r = 0.826; p < 0.05) was found for BV measurements. Within the limitations of this study, MRI overestimated trabecular bone parameters, but with a statistically significant fixed linear offset.

High‐resolution magnetic resonance imaging of trabecular bone in the wrist at 3 tesla: initial results

2005 ◽  
Vol 46 (3) ◽  
pp. 306-309 ◽  
Author(s):  
B. Ludescher ◽  
P. Martirosian ◽  
S. Lenk ◽  
J. Machann ◽  
F. Dammann ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Trabecular Bone ◽  
Spatial Resolution ◽  
Bone Structure ◽  
3 Tesla ◽  
Spongy Bone ◽  
Resonance Imaging ◽  
High Resolution Mri

Purpose: To evaluate the feasibility of high‐resolution magnetic resonance imaging (MRI) of trabecular bone of the wrist at 3 Tesla (3T) in vivo and to assess the potential benefit of the increased resolution for clinical assessment of structural changes in spongy bone. Material and Methods: High‐resolution MRI of the wrist was performed with a whole‐body 3T MR scanner using a dedicated circularly polarized transmit–receive wrist‐coil. Two 3D‐FISP sequences with a spatial resolution of 300×300×300 µm3 in a measuring time of TA = 7:51 min, and 200×200×200 µm3 in TA = 9:33 min were applied. Seven young healthy volunteers and three elderly subjects with suspected osteoporosis were examined. The signal‐to‐noise ratio (SNR) in the optimized setup at 3T was compared to measurements at 1.5T. Results: The images at 3T allow microscopic analysis of the bone structure at an isotropic spatial resolution of 200 µm in examination times of <10 min. Differences in the structure of the spongy bone between normal and markedly osteoporotic subjects are well depicted. The SNR at 3T was found up to 16 times higher than at 1.5T applying unchanged imaging parameters. Conclusion: The proposed high‐resolution MRI technique offers high potential in the diagnosis and follow‐up of diseases with impaired bone structure of hand and/or wrist in clinical applications.

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