SU-FF-T-387: Rotational Total Skin Electron Irradiation Using a Commercially Available Linear Accelerator with a High Dose Rate Total Body Electron Mode

2006 ◽  
Vol 33 (6Part12) ◽  
pp. 2134-2135 ◽  
Author(s):  
M Evans ◽  
M Olivares ◽  
J Seuntjens ◽  
W Parker ◽  
S Devic ◽  
...  
Keyword(s):  
Dose Rate ◽  
Electron Irradiation ◽  
Linear Accelerator ◽  
High Dose Rate ◽  
High Dose ◽  
Electron Mode ◽  
Total Body

Interplay effect on a 6-MV flattening-filter-free linear accelerator with high dose rate and fast multi-leaf collimator motion treating breast and lung phantoms

2018 ◽  
Vol 45 (6) ◽  
pp. 2369-2376 ◽  
Author(s):  
Tucker Netherton ◽  
Yuting Li ◽  
Paige Nitsch ◽  
Simona Shaitelman ◽  
Peter Balter ◽  
...  
Keyword(s):  
Dose Rate ◽  
Linear Accelerator ◽  
High Dose Rate ◽  
High Dose ◽  
Flattening Filter Free ◽  
Multi Leaf Collimator ◽  
Flattening Filter ◽  
Interplay Effect

scholarly journals Fractionated versus single-dose total body irradiation at low and high dose rates to condition canine littermates for DLA-identical marrow grafts

Blood ◽  
1994 ◽  
Vol 83 (11) ◽  
pp. 3384-3389 ◽  
Author(s):  
R Storb ◽  
RF Raff ◽  
FR Appelbaum ◽  
HJ Deeg ◽  
TC Graham ◽  
...  
Keyword(s):  
Dna Repair ◽  
Single Dose ◽  
Dose Rate ◽  
Total Body Irradiation ◽  
High Dose Rate ◽  
Lymphoid Cells ◽  
High Dose ◽  
Dose Rates ◽  
Total Body ◽  
Allogeneic Marrow

Abstract We explored in dogs the immunosuppressive properties of 450 cGy total body irradiation (TBI) delivered from two opposing 60Co sources, as assessed by the criterion of successful engraftment of allogeneic genotypically DLA-identical littermate marrow. Two questions were asked in this study. Firstly, does dose rate affect the immunosuppressive effect of TBI when administered in a single dose? Secondly, does fractionation alter the immunosuppression of TBI when delivered at a very fast dose rate? Dose rates studied included 7 and 70 cGy/min, and fractionation involved four fractions of 112.5 cGy each, with 6-hour minimum interfraction intervals. Six of 7 dogs receiving 450 cGy single- dose TBI at 70 cGy/min showed sustained engraftment of the allogeneic marrow, compared with 1 of 7 dogs receiving single-dose TBI at 7 cGy/min (P = .01). Fractionated TBI at 70 cGy/min resulted in sustained allogeneic engraftment in 3 of 10 dogs, a result that was statistically significantly worse than that with single-dose TBI at 70 cGy/min (P = .03) and not statistically different (P = .24) from that with fractionated TBI delivered at 7 cGy/min (0 of 5 dogs engrafted). A single dose of 450 cGy of TBI delivered at a rate of 70 cGy/min is significantly more immunosuppressive than the same total dose delivered at 7 cGy/min. Fractionated TBI at 70 cGy/min is significantly less immunosuppressive than single-dose TBI at 70 cGy/min and not significantly different from fractionated TBI administered at 7 cGy/min. Results are consistent with the notion that significant DNA repair in lymphoid cells is possible during interfraction intervals at the relatively high dose rate of 70 cGy/min.

Shielding evaluation of a medical linear accelerator vault in preparation for installing a high-dose rate 252Cf remote afterloader

2005 ◽  
Vol 113 (4) ◽  
pp. 428-437
Author(s):  
C. S. Melhus ◽  
M. J. Rivard ◽  
J. KurKomelis ◽  
C. B. Liddle ◽  
F. X. Massé
Keyword(s):  
Dose Rate ◽  
Linear Accelerator ◽  
High Dose Rate ◽  
High Dose ◽  
Medical Linear Accelerator

Total skin electron irradiation therapy in mycosis fungoides using high-dose rate mode: A preliminary experience

2004 ◽  
Vol 0 (0) ◽  
pp. 060720080827114 ◽  
Author(s):  
Dillip K. Parida ◽  
Kaushal K. Verma ◽  
Subhash Chander ◽  
R. C. Joshi ◽  
Goura K. Rath
Keyword(s):  
Dose Rate ◽  
Mycosis Fungoides ◽  
Electron Irradiation ◽  
High Dose Rate ◽  
High Dose ◽  
Irradiation Therapy ◽  
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