SU-FF-I-68: False Positive Analysis of Functional MRI During Simulated Deep Brain Stimulation

2006 ◽  
Vol 33 (6Part4) ◽  
pp. 2012-2012
Author(s):  
HL Liu ◽  
CM Huang ◽  
SN Lim ◽  
WC Kuan ◽  
HM Chen ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
False Positive ◽  
Positive Analysis ◽  
Deep Brain

scholarly journals False-positive analysis of functional MRI during simulated deep brain stimulation: A phantom study

2008 ◽  
Vol 27 (6) ◽  
pp. 1439-1442 ◽  
Author(s):  
Ho-Ling Liu ◽  
Hsin-Mei Chen ◽  
Yu-Chien Wu ◽  
Siew-Na Lim ◽  
Chih-Mao Huang ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
False Positive ◽  
Phantom Study ◽  
Positive Analysis ◽  
Deep Brain

Somatosensory functional MRI tractography for individualized targeting of deep brain stimulation in patients with chronic pain after brachial plexus injury

2019 ◽  
Vol 161 (12) ◽  
pp. 2485-2490
Author(s):  
Witold H. Polanski ◽  
Amir Zolal ◽  
Johann Klein ◽  
Hagen H. Kitzler ◽  
Gabriele Schackert ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Deep Brain Stimulation ◽  
Brachial Plexus ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Brachial Plexus Injury ◽  
Deep Brain

scholarly journals Differential effects of deep brain stimulation and levodopa on brain activity in Parkinson’s disease

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Karsten Mueller ◽  
Dušan Urgošík ◽  
Tommaso Ballarini ◽  
Štefan Holiga ◽  
Harald E Möller ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Significant Interaction ◽  
Brain Activity ◽  
Finger Tapping ◽  
Levodopa Treatment ◽  
Deep Brain

Abstract Levodopa is the first-line treatment for Parkinson’s disease, although the precise mechanisms mediating its efficacy remain elusive. We aimed to elucidate treatment effects of levodopa on brain activity during the execution of fine movements and to compare them with deep brain stimulation of the subthalamic nuclei. We studied 32 patients with Parkinson’s disease using functional MRI during the execution of finger-tapping task, alternating epochs of movement and rest. The task was performed after withdrawal and administration of a single levodopa dose. A subgroup of patients (n = 18) repeated the experiment after electrode implantation with stimulator on and off. Investigating levodopa treatment, we found a significant interaction between both factors of treatment state (off, on) and experimental task (finger tapping, rest) in bilateral putamen, but not in other motor regions. Specifically, during the off state of levodopa medication, activity in the putamen at rest was higher than during tapping. This represents an aberrant activity pattern probably indicating the derangement of basal ganglia network activity due to the lack of dopaminergic input. Levodopa medication reverted this pattern, so that putaminal activity during finger tapping was higher than during rest, as previously described in healthy controls. Within-group comparison with deep brain stimulation underlines the specificity of our findings with levodopa treatment. Indeed, a significant interaction was observed between treatment approach (levodopa, deep brain stimulation) and treatment state (off, on) in bilateral putamen. Our functional MRI study compared for the first time the differential effects of levodopa treatment and deep brain stimulation on brain motor activity. We showed modulatory effects of levodopa on brain activity of the putamen during finger movement execution, which were not observed with deep brain stimulation.

Functional MRI response and correlated electrophysiological changes during posterior hypothalamic nucleus deep brain stimulation

NeuroImage ◽  
2011 ◽  
Vol 56 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Calvin K. Young ◽  
Andrew R. Brown ◽  
Jordan H.B. Robinson ◽  
Ursula I. Tuor ◽  
Jeff F. Dunn ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Hypothalamic Nucleus ◽  
Posterior Hypothalamic Nucleus ◽  
Deep Brain

Intraoperative functional MRI as a new approach to monitor deep brain stimulation in Parkinson's disease

2004 ◽  
Vol 14 (4) ◽  
pp. 686-690 ◽  
Author(s):  
Bettina Sorger ◽  
Ralf Girnus ◽  
Oliver Schulte ◽  
Barbara Krug ◽  
Klaus Lackner ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
New Approach ◽  
Deep Brain

scholarly journals Orientation-selective and directional deep brain stimulation in swine assessed by functional MRI at 3T

NeuroImage ◽  
2021 ◽  
Vol 224 ◽  
pp. 117357
Author(s):  
Julia P. Slopsema ◽  
Antonietta Canna ◽  
Michelle Uchenik ◽  
Lauri J. Lehto ◽  
Jordan Krieg ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Deep Brain

Simultaneous deep brain stimulation and functional MRI of the healthy rat brain

2015 ◽  
Vol 8 (2) ◽  
pp. 351-352
Author(s):  
N. Van Den Berge ◽  
I. Dauwe ◽  
C. vanhove ◽  
B. Descamps ◽  
P. Van Mierlo ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Rat Brain ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Deep Brain

Deep brain stimulation for Parkinson's disease dissociates mood and motor circuits: A functional MRI case study

2003 ◽  
Vol 18 (12) ◽  
pp. 1508-1516 ◽  
Author(s):  
Taresa Stefurak ◽  
David Mikulis ◽  
Helen Mayberg ◽  
Anthony E. Lang ◽  
Stephanie Hevenor ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Functional Mri ◽  
Brain Stimulation ◽  
Motor Circuits ◽  
Deep Brain
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