Target volume dose considerations in proton beam treatment planning for lung tumors

2005 ◽  
Vol 32 (12) ◽  
pp. 3549-3557 ◽  
Author(s):  
Martijn Engelsman ◽  
Hanne M. Kooy
Keyword(s):  
Treatment Planning ◽  
Proton Beam ◽  
Target Volume ◽  
Lung Tumors

EP-1555 TREATMENT PLANNING OF LUNG TUMORS USING TWO DESIGNS OF PLANNING TARGET VOLUME

2012 ◽  
Vol 103 ◽  
pp. S597
Author(s):  
A. Cámara Turbí ◽  
M. Melchor ◽  
F. Candela ◽  
D. Martínez ◽  
M. Asensio ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Planning Target Volume ◽  
Target Volume ◽  
Lung Tumors

The integration of metabolic imaging in stereotactic procedures including radiosurgery: a review

2002 ◽  
Vol 97 ◽  
pp. 542-550 ◽  
Author(s):  
Marc Levivier ◽  
David Wikler ◽  
Nicolas Massager ◽  
Philippe David ◽  
Daniel Devriendt ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Brain Tumors ◽  
Treatment Planning ◽  
Target Volume ◽  
Emission Tomography ◽  
Low Grade ◽  
Content Type ◽  
Positron Emission ◽  
Pet Scanning ◽  
Fine Print

Object. The authors review their experience with the clinical development and routine use of positron emission tomography (PET) during stereotactic procedures, including the use of PET-guided gamma knife radiosurgery (GKS). Methods. Techniques have been developed for the routine use of stereotactic PET, and accumulated experience using PET-guided stereotactic procedures over the past 10 years includes more than 150 stereotactic biopsies, 43 neuronavigation procedures, and 34 cases treated with GKS. Positron emission tomography—guided GKS was performed in 24 patients with primary brain tumors (four pilocytic astrocytomas, five low-grade astrocytomas or oligodendrogliomas, seven anaplastic astrocytomas or ependymomas, five glioblastomas, and three neurocytomas), five patients with metastases (single or multiple lesions), and five patients with pituitary adenomas. Conclusions. Data obtained with PET scanning can be integrated with GKS treatment planning, enabling access to metabolic information with high spatial accuracy. Positron emission tomography data can be successfully combined with magnetic resonance imaging data to provide specific information for defining the target volume for the radiosurgical treatment in patients with recurrent brain tumors, such as glioma, metastasis, and pituitary adenoma. This approach is particularly useful for optimizing target selection for infiltrating or ill-defined brain lesions. The use of PET scanning contributed data in 31 cases (93%) and information that was specifically utilized to adapt the target volume in 25 cases (74%). It would seem that the integration of PET data into GKS treatment planning may represent an important step toward further developments in radiosurgery: this approach provides additional information that may open new perspectives for the optimization of the treatment of brain tumors.

Microwave ablation of lung tumors: a probabilistic approach for simulation‐based treatment planning

2021 ◽  
Author(s):  
Jan Sebek ◽  
Pinyo Taeprasartsit ◽  
Henky Wibowo ◽  
Warren L. Beard ◽  
Radoslav Bortel ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Microwave Ablation ◽  
Probabilistic Approach ◽  
Lung Tumors ◽  
Simulation Based

EQUIVALENT UNIFORM DOSE SENSITIVITY TO CHANGES IN ABSORBED DOSE DISTRIBUTION

2013 ◽  
Vol 06 (01) ◽  
pp. 1250069
Author(s):  
FRANCISCO CUTANDA-HENRÍQUEZ ◽  
SILVIA VARGAS-CASTRILLÓN
Keyword(s):  
Treatment Planning ◽  
Dose Distribution ◽  
Absorbed Dose ◽  
Target Volume ◽  
Simple Expression ◽  
External Beam Radiation ◽  
Equivalent Uniform Dose ◽  
Beam Radiation ◽  
Dose Volume Histograms ◽  
Small Change

Treatment planning in external beam radiation therapy (EBRT) utilizes dose volume histograms (DVHs) as optimization and evaluation tools. They present the fraction of planning target volume (PTV) receiving more than a given absorbed dose, against the absorbed dose values, and a number of radiobiological indices can be computed with their help. Equivalent uniform dose (EUD) is the absorbed dose that, uniformly imparted, would yield the same biological effect on a tumor as the dose distribution described by the DVH. Uncertainty and missing information can affect the dose distribution, therefore DVHs can be modeled as samples from a set of possible outcomes. This work studies the sensitivity of the EUD index when a small change in absorbed dose distribution takes place. EUD is treated as a functional on the set of DVHs. Defining a Lévy distance on this set and using a suitable expansion of the functional, a very simple expression for a bound on the variation of EUD when the dose distribution changes is found. This bound is easily interpreted in terms of standard treatment planning practice.

scholarly journals Conventional 3D staging PET/CT in CT simulation for lung cancer: impact of rigid and deformable target volume alignments for radiotherapy treatment planning

2011 ◽  
Vol 84 (1006) ◽  
pp. 919-929 ◽  
Author(s):  
G G Hanna ◽  
J R Van Sörnsen De Koste ◽  
K J Carson ◽  
J M O'Sullivan ◽  
A R Hounsell ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Treatment Planning ◽  
Target Volume ◽  
Radiotherapy Treatment Planning ◽  
Pet Ct ◽  
Ct Simulation ◽  
Radiotherapy Treatment

scholarly journals Magnetic Resonance Imaging-Based Robotic Radiosurgery of Arteriovenous Malformations

2021 ◽  
Vol 10 ◽  
Author(s):  
Tobias Greve ◽  
Felix Ehret ◽  
Theresa Hofmann ◽  
Jun Thorsteinsdottir ◽  
Franziska Dorn ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Cox Regression ◽  
Target Volume ◽  
Neurological Deficits ◽  
Patient Comfort ◽  
Invasive Treatment ◽  
Cox Regression Analysis ◽  
Robotic Radiosurgery ◽  
Martin Grade ◽  
Cerebral Avms

ObjectiveCyberKnife offers CT- and MRI-based treatment planning without the need for stereotactically acquired DSA. The literature on CyberKnife treatment of cerebral AVMs is sparse. Here, a large series focusing on cerebral AVMs treated by the frameless CyberKnife stereotactic radiosurgery (SRS) system was analyzed.MethodsIn this retrospective study, patients with cerebral AVMs treated by CyberKnife SRS between 2005 and 2019 were included. Planning was MRI- and CT-based. Conventional DSA was not coregistered to the MRI and CT scans used for treatment planning and was only used as an adjunct. Obliteration dynamics and clinical outcome were analyzed.Results215 patients were included. 53.0% received SRS as first treatment; the rest underwent previous surgery, embolization, SRS, or a combination. Most AVMs were classified as Spetzler-Martin grade I to III (54.9%). Hemorrhage before treatment occurred in 46.0%. Patients suffered from headache (28.8%), and seizures (14.0%) in the majority of cases. The median SRS dose was 18 Gy and the median target volume was 2.4 cm³. New neurological deficits occurred in 5.1% after SRS, with all but one patient recovering. The yearly post-SRS hemorrhage incidence was 1.3%. In 152 patients who were followed-up for at least three years, 47.4% showed complete AVM obliteration within this period. Cox regression analysis revealed Spetzler-Martin grade (P = 0.006) to be the only independent predictor of complete obliteration.ConclusionsAlthough data on radiotherapy of AVMs is available, this is one of the largest series, focusing exclusively on CyberKnife treatment. Safety and efficacy compared favorably to frame-based systems. Non-invasive treatment planning, with a frameless SRS robotic system might provide higher patient comfort, a less invasive treatment option, and lower radiation exposure.

Inter- and Intrafractional Movement–Induced Dose Reduction of Prostate Target Volume in Proton Beam Treatment

2008 ◽  
Vol 71 (4) ◽  
pp. 1091-1102 ◽  
Author(s):  
Myonggeun Yoon ◽  
Dongwook Kim ◽  
Dong Ho Shin ◽  
Sung Yong Park ◽  
Se Byeong Lee ◽  
...  
Keyword(s):  
Dose Reduction ◽  
Proton Beam ◽  
Target Volume
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