Real-time 3D surface-image-guided beam setup in radiotherapy of breast cancer

2004 ◽  
Vol 32 (1) ◽  
pp. 65-75 ◽  
Author(s):  
David Djajaputra ◽  
Shidong Li
Keyword(s):  
Breast Cancer ◽  
Real Time ◽  
Image Guided ◽  
3D Surface ◽  
Surface Image

Estimation of heart-position variability in 3D-surface-image-guided deep-inspiration breath-hold radiation therapy for left-sided breast cancer

2013 ◽  
Vol 109 (3) ◽  
pp. 442-447 ◽  
Author(s):  
Tanja Alderliesten ◽  
Anja Betgen ◽  
Paula H.M. Elkhuizen ◽  
Corine van Vliet-Vroegindeweij ◽  
Peter Remeijer
Keyword(s):  
Breast Cancer ◽  
Radiation Therapy ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Deep Inspiration Breath Hold ◽  
Image Guided ◽  
3D Surface ◽  
Surface Image

PD-0488 ROUTINE REAL-TIME IMAGE-GUIDED VERIFICATION OF BREATH HOLD IN BREAST CANCER PATIENTS

2012 ◽  
Vol 103 ◽  
pp. S196
Author(s):  
H. de Boer ◽  
H.J.G. van den Bongard ◽  
W. de Kruijf ◽  
B. van Asselen
Keyword(s):  
Breast Cancer ◽  
Real Time ◽  
Cancer Patients ◽  
Breath Hold ◽  
Breast Cancer Patients ◽  
Image Guided ◽  
Real Time Image ◽  
Time Image

SU-E-J-76: Clinical Use of a Real-Time Surface Image-Guided Positioning and Tracking System in Proton Therapy

2012 ◽  
Vol 39 (6Part7) ◽  
pp. 3670-3670
Author(s):  
W Hsi ◽  
Y Kang ◽  
X Ding ◽  
A Mascia ◽  
E Ramirez ◽  
...  
Keyword(s):  
Real Time ◽  
Proton Therapy ◽  
Tracking System ◽  
Clinical Use ◽  
Image Guided ◽  
Surface Image

WE-DE-209-04: 3D Surface Image-Guided

2016 ◽  
Vol 43 (6Part40) ◽  
pp. 3816-3817
Author(s):  
X. Tang
Keyword(s):  
Image Guided ◽  
3D Surface ◽  
Surface Image

Image-guided near-infrared fluorescent sentinel lymph node mapping in human breast cancer

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e11591-e11591
Author(s):  
S. Troyan ◽  
S. Gibbs-Strauss ◽  
S. Gioux ◽  
R. Oketokoun ◽  
F. Azar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Optical Imaging ◽  
Real Time ◽  
Near Infrared ◽  
Imaging System ◽  
Sulfur Colloid ◽  
Guided Surgery ◽  
Image Guided ◽  
Nir Fluorescence ◽  
Surgical Field

e11591 Background: Breast cancer surgery is presently performed without real-time image-guidance. We have developed a novel optical imaging system for image-guided surgery that uses invisible near-infrared (NIR) fluorescent light to highlight structures on the surgical field with high sensitivity, specificity, and contrast. We have also performed the first human clinical trial of the imaging system in women undergoing SLN mapping for breast cancer. Methods: We used a portable imaging system with an articulating arm that has 6 degrees of freedom, high power LED light source, custom optics, custom software, and sterile drape. The imaging system provided simultaneous and real-time imaging of color video and NIR fluorescence at up to 15 frames per second. N = 6 women with biopsy- confirmed breast cancer undergoing SLN mapping gave informed consent. All subjects received conventional mapping with Tc-99m sulfur colloid using a handheld gamma probe as well as NIR fluorescence-guided SLN mapping using a mixture of indocyanine green (ICG) diluted to a final concentration of 10 μM in human serum albumin (ICG:HSA). Results: The imaging system was easy to position in the operating room, with the articulating arm providing 50” horizontal reach and 70” vertical reach. Working distance to the patient was 18”. NIR fluorescence excitation was 20 mW/cm2 at 760 nm. NIR-depleted white light was 40,000 lux. A total of 1.6 ml of ICG:HSA was injected intra-tumorally and peri-tumorally and the site massaged for 5 min. 8 of 9 SLNs identified by Tc- 99m sulfur colloid were also identified by NIR fluorescence. However, NIR fluorescence identified an SLN, confirmed to have cancer in it, that was not identified by Tc-99m sulfur colloid. These differences were consistent with asynchrony in the injection techniques. Unlike the gamma-ray probe, NIR fluorescence provided high-resolution, large area optical imaging of the surgical field, and helped guide surgical resection. Conclusions: In this 6-patient pilot study, a novel NIR fluorescence optical imaging system was used for the first time, and provided real-time image-guided surgery for SLN mapping of breast cancer. No significant financial relationships to disclose.

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