Red-cell lifetimes calculated from 51 Cr red-cell survival data

1974 ◽  
Vol 1 (2) ◽  
pp. 58-61 ◽  
Author(s):  
J. C. Widman ◽  
E. R. Powsner
Keyword(s):  
Cell Survival ◽  
Survival Data ◽  
Red Cell ◽  
Red Cell Survival

scholarly journals An Evaluation of DFP32 and Cr51 as Methods of Measuring Red Cell Life Span in Man

Blood ◽  
1963 ◽  
Vol 22 (4) ◽  
pp. 459-465 ◽  
Author(s):  
MARTIN J. CLINE ◽  
NATHANIEL I. BERLIN
Keyword(s):  
Life Span ◽  
Cell Survival ◽  
Survival Data ◽  
Red Cell ◽  
Cell Life ◽  
Wide Range ◽  
Red Cell Survival ◽  
Survival Studies ◽  
Good Agreement

Abstract DFP32 or Cr51 red cell survival studies were performed in 39 patients with hematologic disorders. In each case the erythrocyte life span was also determined using the C14-labeled glycine technic. Good agreement was found between the survival data obtained by the DFP32 and the glycine method. The red cell Cr51 T½ failed to reflect moderate shortening of red cell survival in a significant number of cases when a 25 day half-time was taken as the lower limit of normal. The occasional discrepancy between the erythrocyte life spans obtained with labeled glycine and the Cr51 halftime is probably the result of the limitations of the prevalent method of Cr51 data analysis and of the wide range of Cr51 elution rates in disease. Because of its simplicity and reliability, the DFP32 technics appears to be the method of choice for the determination of red cell survival.

scholarly journals ANALYSIS OF RED CELL SURVIVAL DATA

2008 ◽  
Vol 63 (2) ◽  
pp. 398-400 ◽  
Author(s):  
D. A. Noe ◽  
W. R. Bell
Keyword(s):  
Cell Survival ◽  
Survival Data ◽  
Red Cell ◽  
Red Cell Survival

ANALYSIS OF RED CELL SURVIVAL DATA

1987 ◽  
Vol 65 (1) ◽  
pp. 117-117
Author(s):  
A. C. Dornhorst ◽  
Dennis A. Noe ◽  
William R. Bell
Keyword(s):  
Cell Survival ◽  
Survival Data ◽  
Red Cell ◽  
Red Cell Survival

Automated Differential Agglutination Technic to Measure Red Cell Survival

Transfusion ◽  
1968 ◽  
Vol 8 (2) ◽  
pp. 74-83 ◽  
Author(s):  
I. O. Szymanski ◽  
C. R. Valeri
Keyword(s):  
Cell Survival ◽  
Red Cell ◽  
Red Cell Survival

Erythropoiesis and red cell survival in the hypothyroid dog

1963 ◽  
Vol 204 (3) ◽  
pp. 415-418 ◽  
Author(s):  
Martin J. Cline ◽  
Nathaniel I. Berlin
Keyword(s):  
Cell Survival ◽  
Iron Concentration ◽  
Vitamin B ◽  
Dietary Iron ◽  
Red Cell ◽  
Iron Intake ◽  
Turnover Rates ◽  
Erythrocyte Survival ◽  
Red Cell Survival ◽  
Cell Synthesis

Determinations of blood volume, total red cell volume, plasma and red cell iron turnover rates, and red cell survival were performed in seven dogs prior to and subsequent to radioiodine destruction of the thyroid gland. Anemia developed slowly in all animals as a result of a diminished rate of red cell synthesis. Erythrocyte survival was unaffected by thyroid ablation. Serum iron concentration decreased in five animals despite the apparent adequacy of dietary iron intake and the absence of detectable external loss. In two animals, parenteral administration of iron failed to correct the anemia. Vitamin B12 was ineffective in correcting the anemia or in producing a reticulocyte response in two other animals.

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