Michael J. Sailor: Porous Silicon Nanoparticles as Self-Reporting Drug Delivery Vehicles

SPIE Newsroom ◽  
2017 ◽  
Author(s):  
SPIE
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Drug Delivery Vehicles ◽  
Porous Silicon Nanoparticles ◽  
Delivery Vehicles

scholarly journals Drug Delivery: Antibody-Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs (Adv. Healthcare Mater. 5/2013)

2013 ◽  
Vol 2 (5) ◽  
pp. 626-626 ◽  
Author(s):  
Emilie Secret ◽  
Kevin Smith ◽  
Valentina Dubljevic ◽  
Eli Moore ◽  
Peter Macardle ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Hydrophobic Drugs ◽  
Porous Silicon Nanoparticles

Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy

2015 ◽  
Vol 16 ◽  
pp. 206-214 ◽  
Author(s):  
Chang-Fang Wang ◽  
Ermei M. Mäkilä ◽  
Martti H. Kaasalainen ◽  
Marja V. Hagström ◽  
Jarno J. Salonen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Combination Therapy ◽  
Sustained Release ◽  
Cellular Uptake ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Dual Drug

Controlled Delivery of Levothyroxine Using Porous Silicon as a Drug Nanocontainer

2016 ◽  
Vol 69 (2) ◽  
pp. 204 ◽  
Author(s):  
Soheila Kashanian ◽  
Elham Rostami ◽  
Frances J. Harding ◽  
Steven J. P. McInnes ◽  
Sameer Al-Bataineh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Release Kinetics ◽  
Drug Loading ◽  
Controlled Delivery ◽  
Sustained Drug Release ◽  
Drug Delivery Vehicles ◽  
Zero Order Release ◽  
Delivery Vehicles

Porous silicon (pSi) materials are regarded as promising drug delivery vehicles due to their biocompatibility, in vivo degradation, and resorption. We examine pSi films as a platform for the controlled delivery of levothyroxine, as a means to overcome problems with consistent dosage of this drug by oral administration. Oxidized pSi films were modified with 3-(aminopropyl)triethoxysilane (APTES), creating a surface chemistry that increased levothyroxine drug loading capacity by 50 % and sustained drug release under physiological conditions for 14 days. Release kinetics from APTES-functionalized films initially followed a zero-order release profile, which is highly desirable for drug delivery. The loading and release profiles of levothyroxine suggest that the film size required to deliver a therapeutic dose is feasible for further consideration as an implantable delivery system.

scholarly journals Porous silicon nanoparticles for drug delivery

2018 ◽  
Vol 347 ◽  
pp. 012048
Author(s):  
E N Abramova ◽  
A M Khort ◽  
A G Yakovenko ◽  
A I Lvovsky ◽  
E A Slipchenko ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles

Dendrimers: General Aspects, Applications and Structural Exploitations as Prodrug/Drug-delivery Vehicles in Current Medicine

2018 ◽  
Vol 18 (5) ◽  
pp. 439-457 ◽  
Author(s):  
Merina Mariyam ◽  
Kajal Ghosal ◽  
Sabu Thomas ◽  
Nandakumar Kalarikkal ◽  
Mahima S. Latha
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles ◽  
General Aspects
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