Transverse force profiles of individual dielectric particles in an optical trap

Author(s):  
Ming-Tzo Wei ◽  
Jack Ng ◽  
C. T. Chan ◽  
Arthur Chiou ◽  
H. Daniel Ou-Yang
1997 ◽  
Vol 22 (11) ◽  
pp. 816 ◽  
Author(s):  
Ryota Omori ◽  
Tamiki Kobayashi ◽  
Atsuyuki Suzuki

Author(s):  
Steven M. Block

A single beam gradient force optical trap1-3, or “optical tweezers”, exerts forces on microscopic dielectric particles using a highly focused beam of laser light, and can achieve stable, three-dimensional trapping of such particles (for a review, see ref. 4). Using an infrared laser, calibratable forces in the piconewton (pN) range can be easily generated without causing significant damage to living biological specimens. Optical tweezers work through the microscope, without mechanical intrusion within sealed preparations, and can even reach directly inside transparent cells or organelles. Because it is formed by light, an optical trap can be controlled with very high spatial and temporal precision. Its characteristic size (i.e., its “grasp”) is approximately equal to the wavelength of light, but it can be used to capture and/or manipulate objects ranging in size from ∼20 nm to ∼100 mm. Biological preparations (e.g., cells, vesicles, organelles) or small particles (e.g., latex or silica microspheres, perhaps carrying reagents coupled to their surfaces) can be held, maneuvered, or released at will. Already, researchers have begun to contemplate experiments that were practically impossible just a few years ago. Some possibilities include: (1) the sorting and isolation of cells, vesicles, organelles, chromosomes, etc.; (2) the direct measurement of the mechanical properties of cytoskeletal assemblies, membranes, or membrane-bound elements; (3) measurement of the tiny forces produced by mechanoenzymes; (4) establishing cell-cell contacts, or measuring receptor-ligand interactions; (5) studying cellular rheology on the micrometer scale; (6) doing cellular microsurgery, membrane fusion, and building novel cellular (or noncellular) structures; (7) capturing and maintaining fragile biological structures away from vessel surfaces, in order to study them in isolation under optimal viewing conditions; (8) and much more! The principles by which optical tweezers work will be explained, and a videotape illustrating a number of experimental uses will be shown.


2002 ◽  
Author(s):  
Amanda Wright ◽  
Tiffany A. Wood ◽  
Mark R. Dickinson ◽  
Helen F. Gleeson ◽  
Tom Mullin ◽  
...  

2002 ◽  
Author(s):  
Tiffany A. Wood ◽  
Amanda Wright ◽  
Helen F. Gleeson ◽  
Mark Dickenson ◽  
Tom Mullin ◽  
...  

2021 ◽  
Vol 31 (3) ◽  
Author(s):  
Nguyen Manh Thang

In this paper, a model of dual-beam nonlinear Fabry-Perot interferometer (DBNFPI) for creation laser hollow-Gaussian beam (HGB) is investigated. It includes a thin film of organic dye sandwiched between two optical mirrors, and irradiated by two signal and pump laser Gaussian beams. Based on the equation describing the output-input relation of intensities concerning pump intensity and the expression of the spatial intensity distribution of output signal beam (OSB), the range of pump intensity and collection of designed parameters are numerically calculated and discussed for HGB creation. These results give us the opportunity to use DBNFPI for optical trap of low-index dielectric particles.


1986 ◽  
Vol 11 (5) ◽  
pp. 288 ◽  
Author(s):  
A. Ashkin ◽  
J. M. Dziedzic ◽  
J. E. Bjorkholm ◽  
Steven Chu

1980 ◽  
Vol 90 ◽  
pp. 391-394 ◽  
Author(s):  
Keith F. Ratcliff ◽  
Nebil Y. Misconi ◽  
Stephen J. Paddack

Irregular interplanetary dust particles may acquire a considerable spin rate due to two non-statistical dynamical mechanisms induced by solar radiation. These arise from variations in surface albedo as discussed by Radzievskii (1954) and from irregularities in surface geometry as discussed by Paddack (1969). We report on an experiment which will lead to an evaluation in space of the effectiveness of these two spin mechanisms. We utilize the technique of optical levitation in an argon laser beam to provide a stable trap for particles (10-60 microns in diameter). The spin rate and direction of the spin axis are measured in a straightforward manner. The objective is to design an optical trap for dielectric particles in vacuum which can be used to study these rotation mechanisms in the gravity-free environment of a Spacelab experiment.


Author(s):  
David McGloin

In 1986, Arthur Ashkin and colleagues published a seminal paper in Optics Letters , ‘Observation of a single-beam gradient force optical trap for dielectric particles’ which outlined a technique for trapping micrometre-sized dielectric particles using a focused laser beam, a technology which is now termed optical tweezers. This paper will provide a background in optical manipulation technologies and an overview of the applications of optical tweezers. It contains some recent work on the optical manipulation of aerosols and concludes with a critical discussion of where the future might lead this maturing technology.


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