Sensitivity enhancement and detection-limit improvement in whispering-gallery-mode-based biosensing

2012 ◽  
Author(s):  
Bei-Bei Li ◽  
Xu Yi ◽  
Qiu-Shu Chen ◽  
Yong-Chun Liu ◽  
Yun-Feng Xiao
Keyword(s):  
Detection Limit ◽  
Whispering Gallery Mode ◽  
Sensitivity Enhancement ◽  
Whispering Gallery

Enhancing detection limit of whispering gallery mode microcavity for intracellular sensing applications

2021 ◽  
Author(s):  
Jinsong Lu ◽  
Yaping Wang ◽  
Marion C. Lang ◽  
Mingqian Suo ◽  
Shijia Wang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Whispering Gallery Mode ◽  
Whispering Gallery ◽  
Sensing Applications ◽  
Intracellular Sensing

Femtomolar response of a plasmon-coupled ZnO/graphene/silver hybrid whispering-gallery mode microcavity for SERS sensing

2019 ◽  
Vol 7 (9) ◽  
pp. 2710-2716 ◽  
Author(s):  
Qiuxiang Zhu ◽  
Chunxiang Xu ◽  
Delong Wang ◽  
Bing Liu ◽  
Feifei Qin ◽  
...  
Keyword(s):  
Detection Limit ◽  
Whispering Gallery Mode ◽  
Probe Molecule ◽  
Whispering Gallery ◽  
Sers Sensing

A ZnO/graphene/Ag-NP substrate manifested femtomolar SERS sensitivity with an ultralow detection limit down to 10−15 M for probe molecule detection.

Evaluation of Effective Conductivity of Copper-Clad Dielectric Laminate Substrates in Millimeter-Wave Bands Using Whispering Gallery Mode Resonators

2009 ◽  
Vol E92-C (12) ◽  
pp. 1504-1511 ◽  
Author(s):  
Thi Huong TRAN ◽  
Yuanfeng SHE ◽  
Jiro HIROKAWA ◽  
Kimio SAKURAI ◽  
Yoshinori KOGAMI ◽  
...  
Keyword(s):  
Millimeter Wave ◽  
Effective Conductivity ◽  
Whispering Gallery Mode ◽  
Whispering Gallery

A whispering-gallery-mode microlaser based on dual erbium-doped microspheres

2021 ◽  
Vol 142 ◽  
pp. 107254
Author(s):  
Jing Yan ◽  
D.N. Wang ◽  
Xin Liu ◽  
Jikai Chen
Keyword(s):  
Whispering Gallery Mode ◽  
Whispering Gallery ◽  
Erbium Doped

A whispering gallery mode strain sensor based on microtube resonator

2021 ◽  
Vol 17 (4) ◽  
pp. 199-204
Author(s):  
Yu Liu ◽  
Hui-hui Yang ◽  
Yong-le Lu ◽  
Ke Di ◽  
Jun-qi Guo
Keyword(s):  
Strain Sensor ◽  
Whispering Gallery Mode ◽  
Whispering Gallery

scholarly journals Optical whispering-gallery mode barcodes for high-precision and wide-range temperature measurements

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Jie Liao ◽  
Lan Yang
Keyword(s):  
High Precision ◽  
Dynamic Range ◽  
Single Mode ◽  
Whispering Gallery Mode ◽  
Temperature Measurements ◽  
Laser Source ◽  
Multiple Modes ◽  
Whispering Gallery ◽  
Wide Range ◽  
Thermal Sensing

AbstractTemperature is one of the most fundamental physical properties to characterize various physical, chemical, and biological processes. Even a slight change in temperature could have an impact on the status or dynamics of a system. Thus, there is a great need for high-precision and large-dynamic-range temperature measurements. Conventional temperature sensors encounter difficulties in high-precision thermal sensing on the submicron scale. Recently, optical whispering-gallery mode (WGM) sensors have shown promise for many sensing applications, such as thermal sensing, magnetic detection, and biosensing. However, despite their superior sensitivity, the conventional sensing method for WGM resonators relies on tracking the changes in a single mode, which limits the dynamic range constrained by the laser source that has to be fine-tuned in a timely manner to follow the selected mode during the measurement. Moreover, we cannot derive the actual temperature from the spectrum directly but rather derive a relative temperature change. Here, we demonstrate an optical WGM barcode technique involving simultaneous monitoring of the patterns of multiple modes that can provide a direct temperature readout from the spectrum. The measurement relies on the patterns of multiple modes in the WGM spectrum instead of the changes of a particular mode. It can provide us with more information than the single-mode spectrum, such as the precise measurement of actual temperatures. Leveraging the high sensitivity of WGMs and eliminating the need to monitor particular modes, this work lays the foundation for developing a high-performance temperature sensor with not only superior sensitivity but also a broad dynamic range.

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