Biodegradable polymer nanocarriers for therapeutic antisense microRNA delivery in living animals

The article presents options for recycling polymers. The use of biodegradable materials is promising. This is a special class of polymers that can decompose under aerobic or anaerobic conditions under the action of microorganisms or enzymes forming natural products such as carbon dioxide, nitrogen, water, biomass, and inorganic salts. (Research purpose) The research purpose is in reviewing biodegradable materials that can be used for the manufacture of products used in agriculture. (Materials and methods) The study are based on open information sources containing information about biodegradable materials. Research methods are collecting, studying and comparative analysis of information. (Results and discussion) The article presents the advantages and disadvantages of biodegradable materials, mechanical properties of the main groups of biodegradable polymers. The article provides a summary list of agricultural products that can be made from biodegradable polymer materials. It was found that products from the general group are widely used in agriculture. Authors have found that products from a special group can only be made from biodegradable polymers with a controlled decomposition period in the soil, their use contributes to increasing the productivity of crops. (Conclusions) It was found that biodegradable polymer materials, along with environmental safety, have mechanical properties that allow them producing products that do not carry significant loads during operation. We have shown that the creation of responsible products (machine parts) from biodegradable polymers requires an increase in their strength properties, which is achievable by creating composites based on them. It was found that the technological complexity of their manufacture and high cost are the limiting factors for the widespread use of biodegradable polymers at this stage.

Download Full-text

Multifunctional Graphdiyne–Cerium Oxide Nanozymes Facilitate MicroRNA Delivery and Attenuate Tumor Hypoxia for Highly Efficient Radiotherapy of Esophageal Cancer

Advanced Materials ◽

10.1002/adma.202100556 ◽

2021 ◽

pp. 2100556

Author(s):

Xuantong Zhou ◽

Min You ◽

Fuhui Wang ◽

Zhenzhen Wang ◽

Xingfa Gao ◽

...

Keyword(s):

Esophageal Cancer ◽

Cerium Oxide ◽

Tumor Hypoxia ◽

Highly Efficient ◽

Microrna Delivery

Download Full-text

Insights into Biodegradable Polymer-Supported Titanium Dioxide Photocatalysts for Environmental Remediation

Macromol ◽

10.3390/macromol1030015 ◽

2021 ◽

Vol 1 (3) ◽

pp. 201-233

Author(s):

Nina Maria Ainali ◽

Dimitrios Kalaronis ◽

Eleni Evgenidou ◽

Dimitrios N. Bikiaris ◽

Dimitra A. Lambropoulou

Keyword(s):

Titanium Dioxide ◽

Biodegradable Polymers ◽

Biodegradable Polymer ◽

Environmental Remediation ◽

Mechanical Stability ◽

Dip Coating ◽

Tio2 Photocatalysts ◽

Chemical Inertness ◽

Polymeric Substrates ◽

Published Research

During the past two decades, immobilization of titanium dioxide (TiO2), a well-known photocatalyst, on several polymeric substrates has extensively gained ground since it limits the need of post-treatment separation stages. Taking into account the numerous substrates tested for supporting TiO2 photocatalysts, the use of biodegradable polymer seems a hopeful option owing to its considerable merits, including the flexible nature, low price, chemical inertness, mechanical stability and wide feasibility. The present review places its emphasis on recently published research articles (2011–2021) and exhibits the most innovative studies facilitating the eco-friendly biodegradable polymers to fabricate polymer-based photocatalysts, while the preparation details, photocatalytic performance and reuse of the TiO2/polymer photocatalysts is also debated. The biodegradable polymers examined herein comprise of chitosan (CS), cellulose, alginate, starch, poly(lactid acid) (PLA), polycaprolactone (PCL) and poly(lactide-co-glycolide) (PLGA), while an emphasis on the synthetical pathway (dip-coating, electrospinning, etc.) of the photocatalysts is provided.

Download Full-text