The x-space formulation of magnetic particle imaging including non-negligible relaxation effects

2011 ◽  
Author(s):  
Laura R. Croft ◽  
Patrick Goodwill ◽  
Arbi Tamrazian ◽  
Kannan Krishnan ◽  
Steven Conolly
Keyword(s):  
Magnetic Particle ◽  
Relaxation Effects ◽  
Magnetic Particle Imaging ◽  
Space Formulation ◽  
Particle Imaging

scholarly journals Flow velocity quantification by exploiting the principles of the Doppler effect and magnetic particle imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dennis Pantke ◽  
Florian Mueller ◽  
Sebastian Reinartz ◽  
Fabian Kiessling ◽  
Volkmar Schulz
Keyword(s):  
Flow Velocity ◽  
Magnetic Particle ◽  
Imaging Techniques ◽  
Radiation Risk ◽  
Medical Application ◽  
Velocity Estimation ◽  
Magnetic Particle Imaging ◽  
Measurable Velocity ◽  
Depth Dependency ◽  
Particle Imaging

AbstractChanges in blood flow velocity play a crucial role during pathogenesis and progression of cardiovascular diseases. Imaging techniques capable of assessing flow velocities are clinically applied but are often not accurate, quantitative, and reliable enough to assess fine changes indicating the early onset of diseases and their conversion into a symptomatic stage. Magnetic particle imaging (MPI) promises to overcome these limitations. Existing MPI-based techniques perform velocity estimation on the reconstructed images, which restricts the measurable velocity range. Therefore, we developed a novel velocity quantification method by adapting the Doppler principle to MPI. Our method exploits the velocity-dependent frequency shift caused by a tracer motion-induced modulation of the emitted signal. The fundamental theory of our method is deduced and validated by simulations and measurements of moving phantoms. Overall, our method enables robust velocity quantification within milliseconds, with high accuracy, no radiation risk, no depth-dependency, and extended range compared to existing MPI-based velocity quantification techniques, highlighting the potential of our method as future medical application.

Sign in / Sign up

Export Citation Format

Share Document