scholarly journals Micro-CT characterization of human trabecular bone in osteogenesis imperfecta

2011 ◽  
Author(s):  
John Jameson ◽  
Carolyne Albert ◽  
Peter Smith ◽  
Robert Molthen ◽  
Gerald Harris
Keyword(s):  
Osteogenesis Imperfecta ◽  
Trabecular Bone ◽  
Micro Ct ◽  
Human Trabecular Bone

Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone

2015 ◽  
Vol 137 (1) ◽  
Author(s):  
Alexander Zwahlen ◽  
David Christen ◽  
Davide Ruffoni ◽  
Philipp Schneider ◽  
Werner Schmölz ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Bone Structure ◽  
Experimental Studies ◽  
Tissue Level ◽  
Heterogeneous Distribution ◽  
Human Trabecular Bone ◽  
Young’S Moduli ◽  
Failure Assessment ◽  
Experimental Strain

The local interpretation of microfinite element (μFE) simulations plays a pivotal role for studying bone structure–function relationships such as failure processes and bone remodeling. In the past μFE simulations have been successfully validated on the apparent level, however, at the tissue level validations are sparse and less promising. Furthermore, intratrabecular heterogeneity of the material properties has been shown by experimental studies. We proposed an inverse μFE algorithm that iteratively changes the tissue level Young’s moduli such that the μFE simulation matches the experimental strain measurements. The algorithm is setup as a feedback loop where the modulus is iteratively adapted until the simulated strain matches the experimental strain. The experimental strain of human trabecular bone specimens was calculated from time-lapsed images that were gained by combining mechanical testing and synchrotron radiation microcomputed tomography (SRμCT). The inverse μFE algorithm was able to iterate the heterogeneous distribution of moduli such that the resulting μFE simulations matched artificially generated and experimentally measured strains.

Reproducibility and agreement of micro-CT and histomorphometry in human trabecular bone with different metabolic status

2010 ◽  
Vol 29 (4) ◽  
pp. 442-448 ◽  
Author(s):  
Inari S. Tamminen ◽  
Hanna Isaksson ◽  
Antti S. Aula ◽  
Eero Honkanen ◽  
Jukka S. Jurvelin ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Metabolic Status ◽  
Micro Ct ◽  
Human Trabecular Bone

scholarly journals Characterization of Multipotential Mesenchymal Progenitor Cells Derived from Human Trabecular Bone

Stem Cells ◽  
2003 ◽  
Vol 21 (6) ◽  
pp. 681-693 ◽  
Author(s):  
Richard Tuli ◽  
Suraj Tuli ◽  
Sumon Nandi ◽  
Mark L. Wang ◽  
Peter G. Alexander ◽  
...  
Keyword(s):  
Trabecular Bone ◽  
Progenitor Cells ◽  
Mesenchymal Progenitor Cells ◽  
Human Trabecular Bone

scholarly journals Synchrotron Radiation Micro-CT at the Micrometer Scale for the Analysis of the Three-Dimensional Morphology of Microcracks in Human Trabecular Bone

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e21297 ◽  
Author(s):  
Aymeric Larrue ◽  
Aline Rattner ◽  
Zsolt-Andrei Peter ◽  
Cécile Olivier ◽  
Norbert Laroche ◽  
...  
Keyword(s):  
Synchrotron Radiation ◽  
Trabecular Bone ◽  
Three Dimensional ◽  
Micro Ct ◽  
Human Trabecular Bone ◽  
Micrometer Scale
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